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ClinicalTrials.gov public records Last synced Oct 17, 2026, 8:09 PM EDT

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Showing 841–864 of 893 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Weight loss diet Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Integrating the Genetic and Metabolic Faces of Obesity

NCT00285844
View directory record Official record
Conditions
Insulin Resistance, Obesity, Metabolic Syndrome
Interventions
weight loss, thiazolidinedione
Behavioral · Drug
Lead sponsor
Stanford University
Other
Eligibility
30 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 17, 2026, 8:09 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations

NCT00487344
View directory record Official record
Conditions
Obesity
Interventions
Non-Personalized Meal Planning, Personalized Meal Planning and Dietetic Consultation
Procedure
Lead sponsor
Central FITT, Inc
Other
Eligibility
25 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Edmond, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 3, 2007 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Progressive Weight Loss and Metabolic Health

NCT01299519
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Weight Maintenance, Weight Loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Considering Patient Diet Preferences to Optimize Weight Loss

NCT01152359
View directory record Official record
Conditions
Obesity
Interventions
Choice, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 74 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Obesity, Weight Loss, and Cardiovascular Disease Risk

NCT00186459
View directory record Official record
Conditions
Obesity
Interventions
Hypocaloric diet of varying macronutrient composition
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Results available

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

NCT00371293
View directory record Official record
Conditions
Sleep Apnea Syndromes, Inflammation
Interventions
Weight Loss Program, CPAP therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Weight Loss and Exercise for Communities With Arthritis in North Carolina

NCT02577549
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diet & Exercise, Attention Control
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years and older
Enrollment
823 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
3
States / cities
Chapel Hill, North Carolina • Waynesville, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Oct 17, 2026, 8:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Weight and Shape Concern Among Women with High Body Weight

NCT05845866
View directory record Official record
Conditions
Body Image Disturbance, Overweight and Obesity, Weight Loss
Interventions
Modified Body Project, Facts about obesity, myths about weight loss, Lifestyle intervention for weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
25 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Dietary Pork and Egg on Appetite, Meal-patterning, and Weight Loss in Men

NCT00812162
View directory record Official record
Conditions
Weight Loss
Interventions
Energy Restriction
Other
Lead sponsor
Purdue University
Other
Eligibility
21 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Syndrome Diagnosis and Education Trial

NCT00943254
View directory record Official record
Conditions
Metabolic Cardiovascular Syndrome
Interventions
High-Tech Education, Low-Tech Education
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 15, 2010 · Synced Oct 17, 2026, 8:09 PM EDT
Active, not recruiting Not applicable Interventional

FIT Families Multicomponent Obesity Intervention for African American Adolescents

NCT04974554
View directory record Official record
Conditions
Obesity, Childhood, Metabolic Syndrome
Interventions
FIT, Home-Based Family Support
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

ENGAGED: E-Networks Guiding Adherence to Goals for Exercise and Diet

NCT01051713
View directory record Official record
Conditions
Obesity
Interventions
Technology Supported, Standard
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2016 · Synced Oct 17, 2026, 8:09 PM EDT
Terminated Not applicable Interventional

Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients

NCT02174783
View directory record Official record
Conditions
Liver Transplantation, Metabolic Syndrome X, Obesity
Interventions
Control group, Mediterranean diet, Protein-Sparing Modified Fast (PSMF)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Incentivizing Behavior Change Skills to Promote Weight Loss

NCT02691260
View directory record Official record
Conditions
Obesity
Interventions
incentives for dietary self-monitoring, incentives for interim weight loss, incentives for both
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

NCT03174769
View directory record Official record
Conditions
Sleep, Body Composition
Interventions
Normal protein, High protien
Other
Lead sponsor
Purdue University
Other
Eligibility
35 Years to 69 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 20, 2019 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prepackaged Foods to Promote Weight Loss

NCT02136290
View directory record Official record
Conditions
Overweight, Obese
Interventions
Prepackaged meals, Usual Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
25 Years to 65 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2015 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2

NCT04605640
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Diet Habit
Interventions
Weight Management Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 17, 2026, 8:09 PM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the NEXT Steps Weight Loss Intervention +/- Resistance Training for Endometrial Cancer Survivors: Effect on Lean Mass & Biomarkers

NCT02774759
View directory record Official record
Conditions
Malignant Neoplasms of Female Genital Organs
Interventions
Accelerometer, Questionnaires, Fitness Test, Resistance Training, Aerobic Exercise, Telephone Coaching/Phone Calls, Video Chat Sessions
Device · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 17, 2026, 8:09 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Treating Binge Eating and Obesity Digitally in Women

NCT05693896
View directory record Official record
Conditions
Binge Eating, Binge-Eating Disorder, Weight Gain Prevention, Obesity
Interventions
Centering Appetite
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional Results available

Spatz Adjustable Balloon for Obesity (SABO)

NCT02812160
View directory record Official record
Conditions
Obesity
Interventions
Spatz3 Adjustable Balloon
Device
Lead sponsor
Spatz FGIA, Inc
Other
Eligibility
22 Years to 65 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Chicago, Illinois • Metairie, Louisiana • Towson, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race

NCT03771261
View directory record Official record
Conditions
Pre Diabetes, Obesity
Interventions
Weight Loss, Egg Protein
Behavioral · Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 17, 2026, 8:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BRIDGE & Friends Trial

NCT07798557
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Social Network Curriculum
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 79 Years
Enrollment
532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Food is Medicine: Pilot Study

NCT06797453
View directory record Official record
Conditions
Weight Loss
Interventions
Shared Medical Visits, Full Plate Living
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 17, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Weight Loss as Therapy for Heart Failure With Preserved Ejection Fraction

NCT02911337
View directory record Official record
Conditions
Heart Failure, Diastolic, Weight Loss
Interventions
lifestyle modification
Dietary Supplement
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 17, 2026, 8:09 PM EDT