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Showing 1–24 of 564 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Weight loss surgery Clear all
Completed Not applicable Interventional Accepts healthy volunteers

fMRI and Appetite-Related Hormones Pre and Post Obesity Surgery

NCT01583725
View directory record Official record
Conditions
Obesity
Interventions
Liquid meal responses, fMRI responses to food-cues
Procedure · Behavioral
Lead sponsor
New York Obesity and Nutrition Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Hepatic Effects of Gastric Bypass Surgery

NCT00701376
View directory record Official record
Conditions
Liver Diseases
Interventions
liver biopsy
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Sep 13, 2026, 6:22 AM EDT
Completed No phase listed Observational

Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

NCT06401876
View directory record Official record
Conditions
Glucose Intolerance, Insulin Resistance, Diabetes
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 13, 2026, 6:22 AM EDT
Completed No phase listed Observational

Observation of the Incidence and Natural History of MGUS in Patients Undergoing Weight Reduction Surgery

NCT03855878
View directory record Official record
Conditions
Monoclonal Gammopathy of Undetermined Significance
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
30 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vascular Endothelium Changes After Bariatric Surgery (Endothelial Progenitor Cells)

NCT01213940
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
pre-bariatric weight loss program, bariatric surgery
Behavioral · Procedure
Lead sponsor
University of South Alabama
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Promoting Physical Activity Among Bariatric Surgery Patients

NCT01722357
View directory record Official record
Conditions
Obesity
Interventions
Pedometer, Exercise Counseling
Behavioral
Lead sponsor
Ascension St. Vincent Carmel Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 13, 2026, 6:22 AM EDT
Terminated Phase 2 Interventional Results available

The Effect of Surgically Induced Weight Loss on Endocrine Function, Cardiovascular Function and Body Composition

NCT00686972
View directory record Official record
Conditions
Bariatric Surgery
Interventions
GLP-1
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Weight Regain Treatment Post-Bariatric Surgery

NCT04662801
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Behavioral Weight Loss (BWL), Early Responder: BWL continued, Early Non-responder: BWL continued with medication added
Behavioral · Combination Product
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Phase 1 Interventional

Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients

NCT06077214
View directory record Official record
Conditions
Bariatric Surgery Candidate, Post-operative Pain
Interventions
Treatment with liposomal bupivacaine, Treatment with standard bupivacaine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
13 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Reduction of Abdominal Fat

NCT01101997
View directory record Official record
Conditions
Fat Reduction
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
5
States / cities
Sacramento, California • Coral Gables, Florida • Hunt Valley, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2020 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Postoperative Incentive Spirometry on Pulmonary Function and Pulmonary Complications in Bariatric Surgery

NCT02431455
View directory record Official record
Conditions
Obesity, Morbid, Complications of Bariatric Procedures, Pulmonary Atelectasis, Pneumonia
Interventions
Incentive spirometer, No incentive spirometer
Device
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Sep 13, 2026, 6:22 AM EDT
Completed No phase listed Observational

Laparoscopic Revision Gastric Bypass for Weight Recidivism

NCT01040572
View directory record Official record
Conditions
Weight Regain, Weight Recidivism, Obesity Recidivism, Clinically Severe Obesity
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2009 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Determinants of Fat Malabsorption After Roux-en-Y Gastric Bypass

NCT01252511
View directory record Official record
Conditions
Severe Obesity
Interventions
RYGB for surgical treatment of severe obesity
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Phase 4 Interventional

Opioid Free Anesthesia and Bariatric Surgery

NCT04144153
View directory record Official record
Conditions
Postoperative Quality of Recovery
Interventions
Opioid Free Total Intravenous Anesthesia, Total Intravenous anesthesia with opioid
Combination Product
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures

NCT03529461
View directory record Official record
Conditions
Severe Obesity, Hypoxia
Interventions
Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
Device · Other
Lead sponsor
Bristol Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Bristol, Connecticut
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Phase 4 Interventional

A Trial of the Cost Effectiveness of IV Acetaminophen in Bariatric Surgery

NCT02233400
View directory record Official record
Conditions
Hospital Costs, Length of Stay, Postoperative Pain Score, Patient Satisfaction
Interventions
Acetaminophen
Drug
Lead sponsor
St. Luke's Hospital and Health Network, Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Allentown, Pennsylvania • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 7, 2014 · Synced Sep 13, 2026, 6:22 AM EDT
Not listed Not applicable Interventional

Bariatric Surgery Study

NCT03766360
View directory record Official record
Conditions
Depression, Quality of Life, Interpersonal Relations
Interventions
Functional Analytical Psychotherapy (FAP)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 5, 2018 · Synced Sep 13, 2026, 6:22 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

NCT06162715
View directory record Official record
Conditions
Severe Obesity, Obesity, BMI Greater Than 30
Interventions
Tirzepatide, Standard of Care post-gastric bypass
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 13, 2026, 6:22 AM EDT
Not listed Not applicable Interventional

Cryoablation for Benign Gastrointestinal Anastomotic Strictures

NCT04372784
View directory record Official record
Conditions
Esophageal Stricture, Duodenal Stricture, Jejunal Stricture, Anastomotic Stricture of Small Intestine
Interventions
Cryotherapy, Esophagogastroduodenoscopy with Balloon Dilatation
Device · Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cerebrospinal Fluid Biomarkers in Bariatric Surgery

NCT04350892
View directory record Official record
Conditions
Obesity
Interventions
Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD)
Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Pancreatic Enzymes to Restore Digestive Function in Malnourished Gastric Bypass Patients

NCT00510744
View directory record Official record
Conditions
Obesity
Interventions
pancreatic enzyme supplement
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2016 · Synced Sep 13, 2026, 6:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Bariatric Surgery on Insulin

NCT00535600
View directory record Official record
Conditions
Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss, Hyperglycemia
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 96 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 13, 2026, 6:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pharmacogenomics and Post-Operative Nausea and Vomiting

NCT03503292
View directory record Official record
Conditions
Postoperative Nausea
Interventions
Granisetron, Ondansetron
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Sep 13, 2026, 6:22 AM EDT
Completed No phase listed Observational Results available

Hepatic Mitochondrial Function in Youth

NCT03587727
View directory record Official record
Conditions
Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 20 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 13, 2026, 6:22 AM EDT