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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:04 PM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Whey Protein Isolate Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Breakfast and Metabolism in Men

NCT03399812
View directory record Official record
Conditions
Aging
Interventions
Animal protein, Plant protein
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 90 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients

NCT01154400
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Casein protein hydrolysates, Whey protein hydrolysates, Casein protein hydrolysates + LEU, Whey protein hydrolysates + LEU
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study

NCT00942513
View directory record Official record
Conditions
Substrate Absorption, Substrate Oxidation, Glucose Regulation
Interventions
trt 1, trt 2, trt 3, trt 4, trt 5, trt 6, trt 7
Other
Lead sponsor
United States Department of Agriculture (USDA)
Federal
Eligibility
25 Years to 65 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2011 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake

NCT03154606
View directory record Official record
Conditions
Appetitive Behavior
Interventions
Micellar Casein (#1), Micellar Casein (#2), Calcium Caseinate, Sodium Caseinate, Milk Protein Isolate, Pure Protein Blend, Whey Protein Isolate, Native Whey Protein Isolate, Soy Protein, Pea Protein, Native Whey: Micellar Casein (50:50) blend, Carbohydrate Control
Other
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 19, 2026, 2:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Metabolic & Mental Health in Female Healthcare Shift Workers

NCT06158204
View directory record Official record
Conditions
Sleep, Inadequate, Overweight and Obesity, Work Related Stress, Healthy Lifestyle
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

Nutritional Therapy Interventions in Heart Failure

NCT03424265
View directory record Official record
Conditions
Heart Failure NYHA Class II
Interventions
EAA mixture, Placebo (whey protein)
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
60 Years to 89 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults

NCT04048616
View directory record Official record
Conditions
Age-Related Sarcopenia, Muscle Loss
Interventions
whey protein isolate, potassium bicarbonate (KHCO3), microcrystalline cellulose, maltodextrin powder
Dietary Supplement · Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years and older
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 19, 2026, 2:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Lactoferrin-enriched Whey on Iron Status in Females

NCT06232642
View directory record Official record
Conditions
Serum Ferritin
Interventions
Lactoferrin, iron and B12 in Whey Protein, Lactoferrin, Iron and B12 in Rice Protein, Lactoferrin, Iron and B12 in Maltrodextrin
Dietary Supplement
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional

High-protein Oral Supplement Improves Normalized Protein Catabolic Rate and Inflammation Markers

NCT05227755
View directory record Official record
Conditions
Renal Failure, Chronic Kidney Disease Requiring Chronic Dialysis
Interventions
Soy protein isolate, Whey protein isolate
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 19, 2026, 2:04 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Beef Versus Whey Protein: The Gut Showdown Self-Experiment

NCT07477223
View directory record Official record
Conditions
Digestion
Interventions
Beef protein, Chocolate whey protein
Dietary Supplement
Lead sponsor
Efforia, Inc
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Effect of Whey and Soy Protein on the Absorption of Pomegranate Polyphenols in the Human Body

NCT02233478
View directory record Official record
Conditions
Healthy
Interventions
Pomegranate Juice, Soybean Flour Protein, Soy Isolate Protein
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Higher Protein Diet and Exercise for Optimal Weight Loss in Elderly Women

NCT00912210
View directory record Official record
Conditions
Bone and Body Composition, Obesity, Metabolic Syndrome, Physical Function, Quality of Life
Interventions
Whey protein isolate, Maltodextrin powder supplement
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
60 Years to 80 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2009 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preserving Muscle Mass and Function in Bedridden Older Adults

NCT01846130
View directory record Official record
Conditions
Bed Rest
Interventions
Leucine, Exercise, Whey protein
Dietary Supplement · Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
60 Years to 80 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 19, 2026, 2:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Genepro Generation 3 Protein Bioavailability Compared to Whey Protein

NCT04615858
View directory record Official record
Conditions
Absorption; Disorder, Protein, Protein Malabsorption, Protein Intolerance
Interventions
Genepro Generation 3 Protein, Whey Protein
Dietary Supplement
Lead sponsor
Musclegen Research, Inc.
Other
Eligibility
25 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Cary, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 19, 2026, 2:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Protein Supplementation and Fat Mass Loss

NCT03678701
View directory record Official record
Conditions
Obesity
Interventions
Pre-meal 100% whey protein intake
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
19 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Oct 19, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses

NCT07121010
View directory record Official record
Conditions
Cardiometabolic Health
Interventions
Animal-Based Protein Smoothie, Plant-Based Protein Smoothie, Plant-Based Protein Smoothie with Leucine
Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Nutritional Supplementation on Occupational Performance in Firefighters

NCT06172543
View directory record Official record
Conditions
Fatigue
Interventions
Creatine Monohydrate, Control
Dietary Supplement
Lead sponsor
Ward Dobbs
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Nutritional Therapy for Autonomic Dysfunction in Elderly Heart Failure Patients

NCT06256276
View directory record Official record
Conditions
Heart Failure
Interventions
Whey protein powder and L-carnitine, Maltodextrin placebo powder and Psyllium Husk capsules
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
60 Years to 90 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of ProHydrolase® on the Amino Acid, Intramuscular Anabolic Signaling, and Endocrine Response to Resistance Exercise in Trained Males

NCT04144114
View directory record Official record
Conditions
Amino Acids
Interventions
ProHydrolase®, Whey protein, Placebo
Dietary Supplement
Lead sponsor
Deerland Enzymes
Industry
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Protein Quality on Post-exercise Skeletal Muscle and Whole-body Protein Kinetics During Energy Deficit

NCT04004715
View directory record Official record
Conditions
Whole-body Protein Balance, Muscle Protein Synthesis
Interventions
Essential Amino Acid Enriched Whey Protein, Whey Protein, Military Ration Entree
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Ingestion Timing on Body Composition and Biochemical Markers in Resistance-trained Males

NCT05544955
View directory record Official record
Conditions
Hypertrophy, Physical Performance
Interventions
isolate whey protein prior to and immediately after resistance training, isolate whey protein 3 hours prior to and 3 hours after resistance training
Dietary Supplement
Lead sponsor
Marymount University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.

NCT04675775
View directory record Official record
Conditions
Cirrhosis, Ascites, Liver Diseases, Frailty, Sarcopenia, Hepatic Encephalopathy
Interventions
Medically-tailored meals (MTM), Protein supplements, Nutrition education handout
Other · Dietary Supplement · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of an EAA/Whey Composition on Protein Metabolism

NCT03502941
View directory record Official record
Conditions
Sarcopenia
Interventions
6.3 g of EAAs mixture and whey protein isolate, 12.6 g of EAAs mixture and whey protein isolate, 12.6 g of whey protein isolate
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 19, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Blends (Soy, Whey and Casein) for Muscle Synthesis

NCT01358305
View directory record Official record
Conditions
Muscle Synthesis
Interventions
Protein Blend
Other
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 19, 2026, 2:04 PM EDT