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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Whole body cooling Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage

NCT02229513
View directory record Official record
Conditions
Postpartum Hemorrhage, Uterine Atony
Interventions
Uterine Cooling
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 21, 2026, 9:13 PM EDT
Withdrawn Phase 2 Interventional

REperfusion With Cooling in CerebraL Acute IscheMia II

NCT02411877
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.), Zoll Thermogard XP technology with the Quattro catheter
Procedure · Device
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2016 · Synced Sep 21, 2026, 9:13 PM EDT
Withdrawn No phase listed Observational

MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE)

NCT01128673
View directory record Official record
Conditions
Hypoxic Ischemic Encephalopathy
Interventions
mRI
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
Up to 1 Week
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 21, 2026, 9:13 PM EDT
Active, not recruiting No phase listed Observational

A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.

NCT06922955
View directory record Official record
Conditions
Nasal Airway Obstruction
Interventions
Not listed
Lead sponsor
Aerin Medical
Industry
Eligibility
22 Years to 85 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
35
States / cities
Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Low Systemic/High Local Exercise Load in Peds SCD

NCT06387758
View directory record Official record
Conditions
Sickle Cell Anemia in Children
Interventions
Low systemic strength training, Moderate systemic exercise
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 21, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Emergency Room Protocols for Treating Hyperthermia

NCT07433036
View directory record Official record
Conditions
Hyperthermia
Interventions
Passive cooling, Cooling packs, Ice sheets, Body bag cooling, Cold water immersion
Procedure
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Phase 1 Interventional Results available

Reperfusion With Cooling in Cerebral Acute Ischemia

NCT01585597
View directory record Official record
Conditions
Stroke, Acute
Interventions
Zoll- Coolgaurd 3000
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Sep 21, 2026, 9:13 PM EDT
Completed No phase listed Observational Results available

CoolCap Followup Study-Coordination of Participating Centers

NCT00581581
View directory record Official record
Conditions
Neonatal Encephalopathy
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
6 Years to 8 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2013 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tarp Assisted Cooling of Hyperthermic Individuals

NCT04095403
View directory record Official record
Conditions
Healthy
Interventions
Tarp Assisted Cooling, passive cooling
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 21, 2026, 9:13 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Intravascular Cooling in the Treatment of Stroke 2/3 Trial

NCT01123161
View directory record Official record
Conditions
Stroke, Acute
Interventions
hypothermia and anti-shivering treatment, Group1: IV t-PA and normothermia
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
22 Years to 82 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
29
States / cities
Birmingham, Alabama • Los Angeles, California • Newport Beach, California + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 21, 2026, 9:13 PM EDT
Terminated Not applicable Interventional Results available

Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)

NCT01192776
View directory record Official record
Conditions
Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic, Hypoxic-Ischemic Encephalopathy, Ischemic-Hypoxic Encephalopathy
Interventions
Whole-body Cooling
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Hours
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)

NCT07155239
View directory record Official record
Conditions
Hidradenitis Suppurativa (HS)
Interventions
AviClear Lase Treatment, Sham (No Treatment)
Device
Lead sponsor
Wynn Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rosemead, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 21, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional

To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

NCT06247553
View directory record Official record
Conditions
Stroke, Walking, Difficulty, Cardiovascular Injury
Interventions
Gait Training, Leg Cycling Exercise
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of an Investigational Thermal Rehab Machine on Body Cooling in Hyperthermic Individuals

NCT03643835
View directory record Official record
Conditions
Cryotherapy Effect
Interventions
Thermal Rehab Machine, Forearm Ice Towels
Device · Other
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piedmont Aging, Cognition & Exercise Study-2

NCT02312843
View directory record Official record
Conditions
Mild Cognitive Impairment, Prediabetes
Interventions
Exercise/Aerobic, Exercise/Stretching
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years to 89 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 21, 2026, 9:13 PM EDT
Withdrawn Not applicable Interventional

Reperfusion With Cooling in Cerebral Acute Ischemia II

NCT01728649
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Mild Hypothermia
Other
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alesis OSA-1 Obstructive Sleep Apnea Treatment

NCT06949969
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
OSA LLLT treatment device, Sham Comparator
Device
Lead sponsor
Photonica USA, LLC
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Miami, Florida • Miramar, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Terminated Not applicable Interventional

Heat Waves and the Elderly With COPD

NCT06295523
View directory record Official record
Conditions
COPD, Aging, Hyperthermia
Interventions
Water Spray, Control
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
65 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

California Transport Cooling Trial

NCT01683383
View directory record Official record
Conditions
Hypoxic Ischemic Encephalopathy
Interventions
Device (servo-regulated cooling), Control (standard practice)
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
Up to 6 Hours
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
9
States / cities
Loma Linda, California • Madera, California • Oakland, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Sep 21, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury

NCT06841198
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
Interventions
spinal cord transcutaneous stimulation, Ice testing
Device · Procedure
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Military Alerting System for Monitoring Body Temperature During Active Cooling

NCT04431596
View directory record Official record
Conditions
Hyperthermia
Interventions
Forearm cooling, Mist-fan cooling
Device · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 20, 2020 · Synced Sep 21, 2026, 9:13 PM EDT
Terminated Not applicable Interventional

Prime Time for Superficial Femoral Artery (SFA) - The SFA Study

NCT00902317
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Cryoplasty (PolarCath peripheral balloon catheter), Laser Angioplasty (Spectranetics), SilverHawk Atherectomy, Viabahn Endograft, Angioplasty/Stent (Guidant "Absolute" stent)
Procedure · Device
Lead sponsor
Arizona Heart Institute
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2009 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2

NCT05708976
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
Cognitive Behavioral Therapy (CBT), Active Whole-Body Hyperthermia (Active WBH), Sham Whole-Body Hyperthermia (Sham WBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 21, 2026, 9:13 PM EDT
Completed Not applicable Interventional

Study to Warm Up and Cool Down Recreationally Active Males Using Different Protocols.

NCT06874023
View directory record Official record
Conditions
Heat Acclimation and Thermotolerance
Interventions
Passive heating in hot conditions, Active heating + passive heating in hot conditions, Active heating in hot conditions, Active heating at room temperature, Cool vest, Damp neck towel combined with arm cool water immersion, Combination of cooling interventions, Control in thermoneutral room without cooling
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 21, 2026, 9:13 PM EDT