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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:32 AM EDT

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Showing 25–48 of 165 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Whole grain diet Clear all
Completed Phase 1Phase 2 Interventional

The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)

NCT03729479
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Hypertension, PreDiabetes, Overweight and Obesity
Interventions
DASH diet, Very low carbohydrate, ketogenic diet, Extras
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 70 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Paleolithic Diets vs T2D and Improvements in the Metabolic Syndrome

NCT00548782
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Paleolithic diet, ADA ( American Diabetes Association) recommended diet
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

NCT06605898
View directory record Official record
Conditions
Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
Interventions
MIND Diet, Control Diet
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
45 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease

NCT05849012
View directory record Official record
Conditions
Crohn's Disease in Remission
Interventions
Low Sulfur Diet, Usual Diet
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Complete Health Improvement Program (CHIP) Risk Reduction/Claims Evaluation Project

NCT02977884
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias, Overweight and Obesity
Interventions
The Complete Health Improvement Program
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
389 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 1Phase 2 Interventional Results available

The Effect of a Mediterranean Diet Intervention on Cancer-related Fatigue and Mitochondrial Function During Chemotherapy

NCT04534738
View directory record Official record
Conditions
Cancer
Interventions
Mediterranean Diet
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2023 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Sleep2BWell Trial

NCT06565104
View directory record Official record
Conditions
Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity, Weight Loss
Interventions
Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
20 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

NCT05899166
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Ketogenic diet, food delivery and education, Standard diet, food delivery and education
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
5 Years to 12 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Groceries for Residents of Southeastern USA to Stop Hypertension

NCT06891911
View directory record Official record
Conditions
Hypertension, Elevated Blood Pressure, Cardiovascular Diseases, Dietary Intervention
Interventions
Dietitian-Assisted DASH groceries, Self-directed shopping
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prevention of Obesity in Military Communities - Fit4Duty

NCT02679937
View directory record Official record
Conditions
Obesity, Overweight, Adiposity
Interventions
Fit4Duty, Nutrition Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
Bethesda, Maryland • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 2, 2026, 2:32 AM EDT
Withdrawn Not applicable Interventional

Effect of a Plant Rich Diet on in People With Type 2 Diabetes and Obesity

NCT02977039
View directory record Official record
Conditions
Type 2 Diabetes Mellitus in Obese
Interventions
NDPR diet, USDA healthy eating diet
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Is MyPlate Approach to Helping Overweight Patients Lose Weight More Patient-centered?

NCT02514889
View directory record Official record
Conditions
Obesity
Interventions
Calorie-counting, MyPlate
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
261 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Long Beach, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eat Healthy for Families

NCT03394326
View directory record Official record
Conditions
Obesity, Childhood, Energy Density, Diet Quality
Interventions
family-based obesity prevention lifestyle intervention
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
2 Years to 5 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

NCT05839210
View directory record Official record
Conditions
Non Hodgkin Lymphoma, Hodgkin Lymphoma
Interventions
LIFE-L Mediterranean Diet, LIFE-L Home-Based Exercise Program, Supportive Materials
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The OHSU Pregnancy Exercise & Nutrition (PEN) Program

NCT01719406
View directory record Official record
Conditions
Gestational Diabetes
Interventions
Intervention, behavioral lifestyle education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Food as Medicine: Evaluating the Impact of Home-delivered Vegetables and Whole Grains on Diet of Food-insecure Families

NCT04639687
View directory record Official record
Conditions
Food Insecurity, Nutrition Poor
Interventions
Food as Medicine Delivery
Behavioral
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
10 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

The Effects of Diet and Exercise Interventions in Peripheral Artery Disease

NCT03845036
View directory record Official record
Conditions
Claudication, Peripheral Artery Disease
Interventions
DASH Diet plus Home-Based Exercise, Home-Based Exercise
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Not yet recruiting Phase 4 Interventional

Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention

NCT06682351
View directory record Official record
Conditions
Prediabetes / Type 2 Diabetes
Interventions
Metformin, GLP-1A, MED
Drug · Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analysis of MicroBial Metabolites After Eating Refined Food

NCT04308473
View directory record Official record
Conditions
Dietary Habits
Interventions
Ultra-processed Food Meal, Whole Food Meal
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT05268042
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Moderately carbohydrate-restricted diet, Fat-restricted diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Not yet recruiting Not applicable Interventional

Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial

NCT07308483
View directory record Official record
Conditions
Pneumonia
Interventions
Ketogenic feeding, Standard feeding
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fruit and Vegetable Biomarker Discovery

NCT05621863
View directory record Official record
Conditions
Biomarkers
Interventions
Aim 1 Meal Challenge 1, Aim 1 Meal Challenge 2, Aim 1 Meal Challenge 3, Aim 2 Typical American Diet, Aim 2 Typical American Diet Plus Test Foods, Aim 2 Dietary Guidelines for Americans Diet Plus Test Foods
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Not yet recruiting Not applicable Interventional

Mediterranean Dietary Intervention for HS

NCT07800416
View directory record Official record
Conditions
Hidradenitis Suppurativa
Interventions
Mediterranean Diet Counseling, Mediterranean Food Support
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 2, 2026, 2:32 AM EDT