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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–70 of 70 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Whole-body Cooling Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Heat Waves and the Elderly - Cooling Modalities

NCT05484739
View directory record Official record
Conditions
Aging, Hyperthermia
Interventions
Water Spray, Fan, Water Spray and Fan, Control
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neck Cooling as a Non-Invasive Method to Lower Brain Temperature in Healthy Adults

NCT04973085
View directory record Official record
Conditions
Healthy
Interventions
Cold circulated water, Body-temperature circulated water
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 5, 2026, 4:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Emergency Room Protocols for Treating Hyperthermia

NCT07433036
View directory record Official record
Conditions
Hyperthermia
Interventions
Passive cooling, Cooling packs, Ice sheets, Body bag cooling, Cold water immersion
Procedure
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Aerobic Exercise, Resistance Exercise, or Flexibility and Relaxation Training in Inactive Older Female Breast Cancer Survivors

NCT00662103
View directory record Official record
Conditions
Breast Cancer, Cancer Survivor, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults, Psychosocial Effects of Cancer and Its Treatment
Interventions
exercise intervention, laboratory biomarker analysis, questionnaire administration, survey administration, assessment of therapy complications, fatigue assessment and management, management of therapy complications, psychosocial assessment and care
Behavioral · Other · Procedure
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
65 Years to 120 Years · Female only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2015 · Synced Oct 5, 2026, 4:51 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility Study for VCool™ Intranasal Cooling System in Healthy Volunteers

NCT07361588
View directory record Official record
Conditions
Targeted Temperature Management
Interventions
Targeted Temperature Management Intranasal Cooling System
Device
Lead sponsor
NeuroIntact Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 5, 2026, 4:51 AM EDT
Withdrawn Not applicable Interventional

Reperfusion With Cooling in Cerebral Acute Ischemia II

NCT01728649
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Mild Hypothermia
Other
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tarp Assisted Cooling of Hyperthermic Individuals

NCT04095403
View directory record Official record
Conditions
Healthy
Interventions
Tarp Assisted Cooling, passive cooling
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 5, 2026, 4:51 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma

NCT02782715
View directory record Official record
Conditions
Carcinoma, Renal Cell
Interventions
Stereotactic Body Radiation Therapy (SBRT), Microwave Ablation (MWA)
Radiation · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 5, 2026, 4:51 AM EDT
Withdrawn Not applicable Interventional

Mild Hypothermia for COVID-19 ARDS

NCT04570462
View directory record Official record
Conditions
COVID19 ARDS
Interventions
Hypothermia Via Cooling Machine- Arctic Sun 5000
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Study to Warm Up and Cool Down Recreationally Active Males Using Different Protocols.

NCT06874023
View directory record Official record
Conditions
Heat Acclimation and Thermotolerance
Interventions
Passive heating in hot conditions, Active heating + passive heating in hot conditions, Active heating in hot conditions, Active heating at room temperature, Cool vest, Damp neck towel combined with arm cool water immersion, Combination of cooling interventions, Control in thermoneutral room without cooling
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 5, 2026, 4:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury

NCT06841198
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
Interventions
spinal cord transcutaneous stimulation, Ice testing
Device · Procedure
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Phase 4 Interventional Results available

CoolSculpting® Elite for Non-Invasive Fat Reduction

NCT04897867
View directory record Official record
Conditions
Non-invasive Fat Reduction
Interventions
CoolSculpting® Elite System with CoolSculpting® Elite applicators
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Sacramento, California • San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Localized Body Cooling Technology on Sleep and Metabolism in African, American With Overweight and Obesity

NCT05849181
View directory record Official record
Conditions
Overweight or Obesity
Interventions
Moona Device, Inactive Moona Device
Device
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 5, 2026, 4:51 AM EDT
Recruiting No phase listed Observational

Cool Prime Comparative Effectiveness Study for Mild HIE

NCT04621279
View directory record Official record
Conditions
Mild Hypoxic Ischemic Encephalopathy of Newborn
Interventions
Normothermia, Whole body therapeutic hypothermia
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
36 Weeks and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly

NCT01899586
View directory record Official record
Conditions
Elderly, Sedentary
Interventions
Regional Specific Training Stimulus (RSTS), Aerobic Exercise Regimen (AE)
Other
Lead sponsor
Duke University
Other
Eligibility
70 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Phase 1 Interventional Results available

Reperfusion With Cooling in Cerebral Acute Ischemia

NCT01585597
View directory record Official record
Conditions
Stroke, Acute
Interventions
Zoll- Coolgaurd 3000
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piedmont Aging, Cognition & Exercise Study-2

NCT02312843
View directory record Official record
Conditions
Mild Cognitive Impairment, Prediabetes
Interventions
Exercise/Aerobic, Exercise/Stretching
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years to 89 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 5, 2026, 4:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Skin Wetting in Burn Survivors

NCT06529757
View directory record Official record
Conditions
Burn Injury
Interventions
Whole body cooling, Non-cooling
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure

NCT00670124
View directory record Official record
Conditions
Acute Liver Failure, Intracranial Hypertension
Interventions
Hypothermia by the use of Blanketrol II, Cincinnati Sub-Zero
Device
Lead sponsor
Copenhagen University Hospital, Rigshospitalet
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 5, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cooling Vest May Reduce Heat Stress During Surgery

NCT04511208
View directory record Official record
Conditions
Body Temperature Changes
Interventions
Cooling Vest, Without cooling vest
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 5, 2026, 4:51 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

LBNP Tolerance With Skin Warming After Exercise Cold Stress

NCT06279897
View directory record Official record
Conditions
Blood Pressure, Blood Loss
Interventions
Skin Surface Rewarming, Skin Surface Warming, Skin Surface Heating, Skin Surface Cooling
Other
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 5, 2026, 4:51 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BATokines as Biomarkers of Brown Fat in Humans

NCT05050240
View directory record Official record
Conditions
Healthy Lifestyle
Interventions
Cooling Vest Procedure, Fasting overnight
Other
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 28 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 5, 2026, 4:51 AM EDT