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ClinicalTrials.gov public records Last synced Nov 4, 2026, 6:41 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 774 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Without exercise Clear all

Conditions: Peripheral Arterial Disease
Interventions: Supervised exercise therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiovascular Diseases, Blood Pressure, Glycated Hemoglobin (HbA1c), Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Indoor Air Quality, Particulate Matter, Health Behavior
Interventions: Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control; Behavioral · Other
Lead sponsor: University of Montana; Other
Eligibility: 55 Years to 79 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Missoula, Montana

Conditions: Total Knee Arthroplasty (TKA)
Interventions: Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 90 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 4
States / cities: Gainesville, Florida

Conditions: Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress, Adolescent Development, Family Research
Interventions: CookingMatters, Parent Education, Physical Activity, Health Education, Mindfulness-based Stress Reduction, Brief Mindfulness Intervention; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 12 Years to 15 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Fort Collins, Colorado

Conditions: Gynecologic Cancer
Interventions: Fitbit, Fitbit + Game + Support from a Teammate; Other
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Brewer, Maine • Boston, Massachusetts • Providence, Rhode Island

Conditions: Tetraplegia/Tetraparesis
Interventions: BES + TS, Experimental: BES+sham TS; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 3
States / cities: Richmond, Virginia

Conditions: Mild Cognitive Impairment
Interventions: Curcumin, aerobic yoga, non aerobic yoga, Placebo; Drug · Behavioral · Dietary Supplement
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: West Los Angeles, California

Conditions: Diabetes, Senior Syndrome, Frailty
Interventions: Diet, Exercise, Diet and exercise; Behavioral
Lead sponsor: Florida International University; Other
Eligibility: 60 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 4
States / cities: Miami, Florida • Sweetwater, Florida

Conditions: Interstitial Cystitis
Interventions: Lidocaine Releasing Intravesical System - LiRIS®, LiRIS Placebo, Sham Cystoscopy Procedure; Drug · Other · Procedure
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 27
States / cities: Glendale, Arizona • Glendora, California • Stanford, California + 24 more

Conditions: Stroke, Hemiparesis, Hemiplegia
Interventions: Electrical stimulator; Device
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Anxiety Disorders
Interventions: Behaviorally Enhanced Training, Standard Didactic Training; Other
Lead sponsor: Bradley Hospital; Other
Eligibility: 21 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Riverside, Rhode Island

Conditions: Multiple Sclerosis
Interventions: Forced Aerobic Exercise (FE), Voluntary Aerobic Exercise (VE); Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Cleveland, Ohio

Conditions: Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer, Survivorship, Endometrial Cancer, Head and Neck Cancers, Prostate Cancers, Geriatric Oncology, Metastatic Breast Cancer, Metastatic Cancer
Interventions: Digital Health Coaching Program, Fitbit; Behavioral · Device
Lead sponsor: Pack Health; Industry
Eligibility: 18 Years and older
Enrollment: 625 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 7
States / cities: Gainesville, Florida • Boston, Massachusetts • Omaha, Nebraska + 3 more

Conditions: Peripheral Artery Disease
Interventions: Daily Step-based Exercise, Symptom-based Exercise, Fitbit Fitness Monitor; Behavioral · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Amputation
Interventions: Passive-elastic prosthetic foot, Powered ankle-foot prosthesis; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 67 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Anterior Shoulder Dislocation, Recurrent Shoulder Dislocation, Shoulder Subluxation, Surgery
Interventions: Blood flow restriction therapy, Standard Physical Thearapy; Other
Lead sponsor: Keller Army Community Hospital; Federal
Eligibility: 17 Years to 30 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: West Point, New York

Conditions: Obesity, Obesity, Childhood, Obesity; Familial
Interventions: Home visitation + HABITS program, Standard home visitation program; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 0 Years to 75 Years
Enrollment: 296 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Type 1 Diabetes
Interventions: MPC AP algorithm, Robust R-AP algorithm; Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Multiple Sclerosis, Lung Cancer, Breast Cancer
Interventions: CT-100-D-004-A, CT-100-D-004-B; Device
Lead sponsor: Click Therapeutics, Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
Interventions: Videogame-based physical activity, Sedentary videogame, Bupropion, Counseling; Behavioral · Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Low Back Pain
Interventions: Experimental Intervention, Placebo Comparator; Other
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older
Enrollment: 264 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services, Patient Participation, Health Behavior, Aging, Cardiovascular Diseases, Metabolic Syndrome, Cognitive Dysfunction, Frailty, Activities of Daily Living, Health Related Quality of Life, Health Equity, Telemedicine
Interventions: AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation; Behavioral
Lead sponsor: William Brandenburg, MD; Industry
Eligibility: 18 Years and older
Enrollment: 1,000,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2099
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Colon Cancer
Interventions: Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires; Other · Procedure
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 30 Years to 80 Years
Enrollment: 3,315 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Distorted; Balance, Motor Deficit
Interventions: Balance Training; Other
Lead sponsor: University of Arizona; Other
Eligibility: 65 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Tucson, Arizona

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Functional MRI of the Lower Extremities

Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults

Total Knee Arthroplasty Biomechanics

United for Health: Type 2 Diabetes Prevention in Latino Teens

Step Into Support for Endurance and Strength (SISTERS)

Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia

Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

Piloting Diet and Exercise Interventions in Older Hispanics With Diabetes

Double-Blind Placebo Controlled Study of Safety,Tolerability, and Efficacy of LiRIS® in Women With Interstitial Cystitis

Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors

Examining Behavioral Strategies for Enhancing Therapists' Delivery of Exposure Therapy

The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis

Comprehensive Outcomes for After Cancer Health

Daily Step-based Exercise Using Fitness Monitors for Peripheral Artery Disease

Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?

Blood Flow Restriction Training Versus Standard Physical Therapy After Shoulder Stabilization Surgery

Healthy Homes, Healthy Habits

Two Way Crossover Closed Loop Study R-AP vs MPC

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

Worksite Exercise Interventions for Low Back Injury Prevention in Firefighters

Health Ahead Comparative Effectiveness Study

Screening and Risk Factors of Colon Neoplasia

Virtual Reality-based Exercise in Older Adults