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Showing 1–24 of 379 matching trials from the live ClinicalTrials.gov search.
Completed No phase listed Observational Accepts healthy volunteers

Working Memory Changes With Aging and Hearing Loss

NCT01253031
Conditions
Aging, Hearing Loss
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Schizophrenia
Interventions
Neurofeedback
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Parkinson Disease
Interventions
Neural recordings and stimulation
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Results available

Remediation of Working Memory in Schizophrenia

NCT00995553
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Cognitive Remediation, Computer Skills
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Choline Dose Ranging in Postmenopausal Women

NCT06924541
Conditions
Menopause
Interventions
Choline, Placebo
Dietary Supplement
Lead sponsor
Julie Dumas
Other
Eligibility
50 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults

NCT05672771
Conditions
Cognitive Aging
Interventions
Different Mixed Condition (DM), Different Single Condition (DS), Same Task (ST) Practice Control, Non-WM Placebo Control (PC)
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
60 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Not listed Not applicable Interventional

Serious Games for Parkinson's Disease

NCT05551338
Conditions
Parkinson Disease, Parkinson
Interventions
Serious games
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Recruiting Not applicable Interventional Accepts healthy volunteers

Cerebellar Involvement in Cognitive Sequencing

NCT06108336
Conditions
Effects of Cerebellar Stimulation on Brain Activation
Interventions
TMS during sequence-demanding task, No TMS during sequence-demanding task, TMS during non-sequence-demanding task, No TMS during non-sequence-demanding task
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Attention-Deficit/Hyperactivity Disorder (Combined-subtype)
Interventions
Working memory training, Functional magnetic resonance imaging (fMRI)
Behavioral · Device
Lead sponsor
Hartford Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Schizophrenia
Interventions
Cognitive remediation therapy
Behavioral
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Conditions
Cognitive Change
Interventions
N-back, Span, Multisensory
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
50 Years to 85 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Irvine, California • Riverside, California
Conditions
Language Delay, Substance Use Disorders, Language Disorders in Children, Language Development, Prevention Intervention
Interventions
Comilia Group, Interaction Review Enhancement, Practical Support Enhancement
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years and older
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Executive Dysfunction, Cognitive Impairment
Interventions
ASCEND-I
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
30 Years to 89 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional

Memory Training and Neural Plasticity

NCT05380739
Conditions
Mild Cognitive Impairment
Interventions
Working Memory Training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Schizophrenia
Interventions
Brain Fitness Program (BFP), Cognitive Package (Cogpack), Commercial Computer Games (Sporcle)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
25 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California • West Los Angeles, California
Conditions
ADHD
Interventions
EWM Training, Placebo Training
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Completed Phase 1 Interventional Accepts healthy volunteers

The Nicotinic Cholinergic System and Cognitive Aging

NCT03408574
Conditions
Healthy Aging
Interventions
Nicotine patch, oral mecamylamine, placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Burlington, Vermont
Not listed Not applicable Interventional Accepts healthy volunteers

ACAR Brain Health Intervention Study

NCT04208880
Conditions
Aging Well
Interventions
TBH Brain Workout 1.0, Brain Health Book Club, TBH Brain Workout 2.0, TBH Memory 1.0, TBH Memory 2.0
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
60 Years and older
Enrollment
294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Conditions
High Grade Glioma
Interventions
PET-MRI Brain Scan, Blood draw, Memory testing, Optional lumbar puncture for cerebrospinal fluid collection
Procedure · Diagnostic Test · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Terminated No phase listed Observational Accepts healthy volunteers

Brain Areas Involved in Sound and Spoken Word Memory

NCT01375595
Conditions
Brain Mapping, Language Disorder, Adult, Healthy, Memory Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Hearing Loss, Sensorineural
Interventions
Hearing aid
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Malignancy, Glioma, Radiotherapy
Interventions
Photon treatment plans, Proton Treatment Plans, Neurocognitive evaluation, Advanced MRI imaging
Radiation · Behavioral · Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Self-regulation, Medication Adherence
Interventions
Self-Regulation Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
HIV-ASSOCIATED NEUROCOGNITIVE DISORDER (HAND)
Interventions
Not listed
Lead sponsor
East Tennessee State University
Other
Eligibility
25 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Johnson City, Tennessee