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Showing 25–48 of 97 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State

NCT04010461
Conditions
Healthy
Interventions
TMS, n-back working memory task
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 50 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Major Depressive Disorder
Interventions
Left DLPFC tDCS, Right DLPFC tDCS, Cognitive task
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Ischemia, Stress, Mental
Interventions
Coronary CT Angiography, Mood Symptom Scale, Anxiety Symptom Scale, Chronic Stress Inventories, Psychosocial Function Questionnaires, General Health and quality of life questionnaires, Magnetic Resonance Imaging
Radiation · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Executive Function Training for Children and Adolescents

NCT07147894
Conditions
Cognitive Change
Interventions
Nongamified N-back training, Gamified N-back training, Multiple Domain Training, Coaching Session
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
12 Years to 17 Years
Enrollment
780 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Cognitive Training for PTSD

NCT03316196
Conditions
Posttraumatic Stress Disorder
Interventions
COGENT COGNITIVE TRAINING, Non training computer condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Diego, California
Conditions
Working Memory, Emotions
Interventions
Working Memory Task, Reward Learning Task, Facial Emotion Recognition Task
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Phase 1 Interventional Accepts healthy volunteers

The Nicotinic Cholinergic System and Cognitive Aging

NCT03408574
Conditions
Healthy Aging
Interventions
Nicotine patch, oral mecamylamine, placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Cognitive Remediation, Computer Games
Behavioral
Lead sponsor
Wesleyan University
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Hartford, Connecticut • Middletown, Connecticut
Completed Not applicable Interventional Results available

Early Cognitive Intervention in Delirium

NCT04740567
Conditions
Delirium, Cognitive Decline, Dementia
Interventions
Cognitive Training, Goal Management Training
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
65 Years and older
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Nashville, Tennessee
Conditions
Epilepsy
Interventions
Luminosity Trial Memory Match, Luminosity Trial Memory Matrix, Luminosity Trial Famliar Faces, Luminosity Trial Brain Shift, Luminosity Trial Star Search, Luminosity Trial Word Bubbles, Luminosity Trial Color Match, Luminosity Trial Ebb and Flow, Luminosity TrialChalk Board Challenge, Luminosiuty Follow that Frog, Luminosity Train of Thought
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional

Neural Basis of Human Working Memory

NCT07617506
Conditions
Memory Disorders
Interventions
Neurocognitive Tasks, Ripple Neuromed Summit System
Behavioral · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Screening Made Easy for PCPs - Administrative Supplement

NCT06928298
Conditions
Cognitive Impairment, Cognitive Decline, Dementia, Mild
Interventions
RACS app
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Austin, Texas • San Antonio, Texas
Conditions
Opioid Use Disorder
Interventions
Working Memory Task, Visual Search Task
Other
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Belmont, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

TMS for Investigating Memory Facilitation

NCT05462782
Conditions
Age-associated Memory Impairment
Interventions
Transcranial Magnetic Stimulation (TMS) Cone Coil, Transcranial Magnetic Stimulation (TMS) Sham Coil
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
60 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neuromodulation Effects in Older Adults

NCT06665022
Conditions
Cognitive Impairment, Cognitive Decline
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Traumatic Brain Injury (TBI), Posttraumatic Stress Disorder (PTSD)
Interventions
CALM (Cognitive Apps for Life Management), Psychoeducation
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Withdrawn Not applicable Interventional Accepts healthy volunteers

TMS of Visual Working Memory

NCT02927470
Conditions
Occipital Transcranial Magnetic Stimulation
Interventions
Sham TMS condition, OffLine TMS Condition, Online TMS condition
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Opioid Use, Cognitive Change, Opioid-use Disorder
Interventions
CogMed
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Impulsive Behavior, Mental Disorders
Interventions
Cognitive Control Training
Other
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Belmont, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects

NCT01600885
Conditions
NMDA Receptor Function
Interventions
Guanfacine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
3
States / cities
New Haven, Connecticut • West Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Obesity Treatment Enhanced With Working Memory Training

NCT02529397
Conditions
ADHD, Weight Loss
Interventions
Adaptive Working Memory Training, Non-adaptive cognitive training
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Completed No phase listed Observational Accepts healthy volunteers Results available

Dual-Task Cost in Bilateral Hearing Loss

NCT05540535
Conditions
Bilateral Hearing Loss, Healthy Aging
Interventions
Gait assessment, Cognitive assessment
Other
Lead sponsor
New York University
Other
Eligibility
40 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New York, New York
Conditions
Obsessive Compulsive Disorder
Interventions
Cognitive Control Training, Peripheral Vision Task
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts