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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:24 PM EDT

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Showing 49–72 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Working Memory Task Clear all
Completed No phase listed Observational Accepts healthy volunteers

Synaptic Injury and Functional Connectivity in Alzheimer's Disease

NCT03300726
View directory record Official record
Conditions
Alzheimer Disease, Late Onset
Interventions
CSF analysis, Functional MRI
Diagnostic Test · Radiation
Lead sponsor
Ohio State University
Other
Eligibility
60 Years to 95 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional

NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits

NCT05662280
View directory record Official record
Conditions
Working Memory
Interventions
Active Intermittent Theta Burst Stimulation, Sham Intermittent Theta Burst Stimulation
Device
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Control Functions of the Human Thalamus

NCT06920992
View directory record Official record
Conditions
Stroke
Interventions
measuring cognitive flexibility including working memory and set-switching
Behavioral
Lead sponsor
Kai Hwang
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

NCT07641244
View directory record Official record
Conditions
Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders, Inflamation, Poverty
Interventions
Psychological fMRI task
Other
Lead sponsor
Northwestern University
Other
Eligibility
10 Years to 18 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

Cognitive Screening Made Easy for PCPs - R33 Phase

NCT06162026
View directory record Official record
Conditions
Cognitive Impairment, Dementia, Mild, Cognitive Decline
Interventions
RACS app
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
60 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of THC on Emotional Memory Retrieval

NCT03471585
View directory record Official record
Conditions
Healthy
Interventions
THC, Placebo oral capsule
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Phase 2Phase 3 Interventional

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

NCT06273527
View directory record Official record
Conditions
Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions
COGENT, Sham Program
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Older Adults, Methadone, and Cognitive Function

NCT07153029
View directory record Official record
Conditions
Opioid Use Disorder, Cognitive Ability General
Interventions
Smartphone based cognitive tasks
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional

tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study

NCT04925453
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
active tDCS and cognitive training intervention, sham tDCS and cognitive training intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Theta Connectivity in Working Memory

NCT05204381
View directory record Official record
Conditions
Executive Function
Interventions
Theta-frequency near-zero phase lag stimulation, Theta-frequency anti-synchrony stimulation, Arrhythmic near-zero phase lag stimulation, Arrhythmic independent stimulation, Alpha-frequency near-zero phase lag stimulation, Alpha-frequency anti-synchrony stimulation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Speech Perception and High Cognitive Demand

NCT04997577
View directory record Official record
Conditions
Speech Intelligibility, Aging
Interventions
Auditory-cognitive training paradigm, Auditory training paradigm
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
65 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 21, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

NCT04105530
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Transcranial Direct Current Stimulation, Executive Dysfunction
Interventions
Anodal tDCS treatment, Cathodal tDCS treatment, Sham treatment, NIH Toolbox List Sorting Working Memory Test, NIH Toolbox Flanker Inhibitory Control and Attention Test, Grooved Peg Board Test, Buschke Selective Reminding Test
Device · Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
8 Years to 215 Months
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Video Game Play to Alleviate Adolescent Anxiety

NCT05923944
View directory record Official record
Conditions
Anxiety, Anxiety Disorders and Symptoms
Interventions
Eco-Rescue, Bejelewed 3
Behavioral
Lead sponsor
School of Health Sciences Geneva
Other
Eligibility
11 Years to 15 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spatial Cues, Task Demands, and Auditory Selective Attention

NCT07765186
View directory record Official record
Conditions
Bilateral Cochlear Implants, Hearing Loss, Bilateral, Healthy
Interventions
Existing bilateral cochlear implants, Normal Hearing Control
Device · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 1:24 PM EDT
Withdrawn Not applicable Interventional

Effects of Cognitive and Emotional Functioning on Treatment Outcomes

NCT03050632
View directory record Official record
Conditions
Eating Disorders
Interventions
N-back, White Bear Task
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Expectation of Unpleasant Events in Anxiety Disorders

NCT00055224
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Threat of shock
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
921 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Working Memory Training Combined With Transcranial Magnetic Stimulation in Smokers

NCT03337113
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Working Memory Training, Sham Working Memory Training, repetitive Transcranial Magnetic Stimulation, Sham repetitive Transcranial Magnetic Stimulation
Other · Device
Lead sponsor
Kent State University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional

A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan

NCT01616797
View directory record Official record
Conditions
Depression, Anxiety, Cognitive Training, Emotion Training, Emotion Regulation
Interventions
Computerized neurobehavioral intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)

NCT01124721
View directory record Official record
Conditions
ADHD, Attention
Interventions
Cognitive training, Cognitive training-placebo
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
7 Years to 14 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Accelerated TMS to a Novel Brain Target in MDD and PTSD

NCT03114891
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target
Device · Behavioral · Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Functional Neuroimaging Effects of Cognitive Remediation Training

NCT00481156
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Remediation, Cognitive Behavioral Social Skills Training, Retest in Health Controls
Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Individual Differences in Working Memory Training and Transfer in Older Adults

NCT05396586
View directory record Official record
Conditions
Cognitive Change
Interventions
N-back, Span, Multisensory
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
50 Years to 85 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Irvine, California • Riverside, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Oct 21, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI

NCT01036711
View directory record Official record
Conditions
Nicotine Dependence, Drug Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 21, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INSIGHT, A Comprehensive, Multidisciplinary Brain Training System

NCT02780739
View directory record Official record
Conditions
Cognitive Ability, General
Interventions
Cognitive Training - 48 sessions, Fitness, Active Control, active tDCS, sham tDCS, Cognitive Training - 20 sessions
Behavioral · Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 44 Years
Enrollment
521 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Oct 21, 2026, 1:24 PM EDT