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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Zinc Supplementation Clear all
Completed Phase 1 Interventional

Burn Micronutrient Repletion Pilot Study

NCT00879723
View directory record Official record
Conditions
Burn
Interventions
Vitamin and Mineral supplementation
Dietary Supplement
Lead sponsor
Southern Illinois University
Other
Eligibility
19 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Folic Acid and Zinc Supplementation Trial (FAZST)

NCT01857310
View directory record Official record
Conditions
Pregnancy, Live Birth, Spontaneous Abortion
Interventions
5 mg folic acid and 30 mg elemental zinc, Placebo Comparator: Placebo
Dietary Supplement · Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 45 Years
Enrollment
2,370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
4
States / cities
Chicago, Illinois • Iowa City, Iowa • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya.

NCT01166815
View directory record Official record
Conditions
Diarrhea, Malaria
Interventions
Zinc sulphate, Placebo
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 55 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Natick, Massachusetts • Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2010 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional

Effect of Omega-3-fatty Acids on Blood Levels Omega-3 Fatty Acids in Patients With Age-related Macular Degeneration

NCT01653184
View directory record Official record
Conditions
Macular Degeneration
Interventions
Omega-3 fatty acid
Dietary Supplement
Lead sponsor
Wills Eye
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Cherry Hill, New Jersey • Bethlehem, Pennsylvania • Huntingdon Valley, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2016 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Supplementation in Alcoholic Cirrhosis

NCT02072746
View directory record Official record
Conditions
Alcoholic Cirrhosis
Interventions
Zinc, Placebo
Dietary Supplement
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 21, 2021 · Synced Sep 10, 2026, 1:31 AM EDT
Withdrawn No phase listed Observational

Zinc Supplementation Improves Cardiovascular Morbidity in Patients With Diabetes Mellitus

NCT05000762
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions
Zinc
Dietary Supplement
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 2 Interventional Results available

Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis

NCT04072822
View directory record Official record
Conditions
Alcoholic Hepatitis
Interventions
Anakinra and Zinc, Prednisone, Placebos
Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Jacksonville, Florida • Indianapolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Results available

Zinc Supplementation and Cardiovascular Risk in HIV

NCT02856269
View directory record Official record
Conditions
HIV, Inflammation
Interventions
Zinc gluconate
Dietary Supplement
Lead sponsor
Grace McComsey
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Sep 10, 2026, 1:31 AM EDT
Not listed Not applicable Interventional

Immunonutrition in Ulcerative Colitis

NCT03594708
View directory record Official record
Conditions
Ulcerative Colitis
Interventions
Nutrition supplement, Placebo supplement
Dietary Supplement
Lead sponsor
Baptist Memorial Health Care Corporation
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 19, 2018 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Community Trial of Zinc Supplementation on Preschool Child Mortality and Morbidity in Southern Nepal

NCT00109551
View directory record Official record
Conditions
Nutrition
Interventions
zinc sulphate dietary supplement, iron sulphate-folic acid dietary supplement
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
1 Month to 36 Months
Enrollment
58,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
2
States / cities
Baltimore, Maryland • Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional

Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation

NCT04342728
View directory record Official record
Conditions
COVID, Corona Virus Infection
Interventions
Ascorbic Acid, Zinc Gluconate, Ascorbic Acid and Zinc Gluconate, Standard of Care
Dietary Supplement · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Weston, Florida • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 4 Interventional

Effects of Glucosamine and Chondroitin Supplementation in Women With Knee Osteoarthritis Participating in an Exercise and Weight Loss Program

NCT01271218
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Diet, Exercise
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2011 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc and Diabetes in Patients With Thalassemia: a Pilot Study

NCT01772680
View directory record Official record
Conditions
Thalassemia
Interventions
Zinc Supplementation
Dietary Supplement
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
12 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 10, 2026, 1:31 AM EDT
Not listed Not applicable Interventional

Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG

NCT04117022
View directory record Official record
Conditions
Diabetes, Diabetic Retinopathy
Interventions
DVS supplementation
Dietary Supplement
Lead sponsor
ZeaVision, LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Pomona, California • Tahlequah, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Supplement Before or With Food in Generally Healthy Men

NCT03619421
View directory record Official record
Conditions
Zinc Deficiency, Dyslipidemias, Zinc Excess, Inflammation
Interventions
Zinc supplement
Dietary Supplement
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional

Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer

NCT03819088
View directory record Official record
Conditions
Gastric Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Unresectable Esophageal Carcinoma, Unresectable Pancreatic Carcinoma
Interventions
Zinc
Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults

NCT02876315
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Redoxon VI, placebo
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
55 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

NCT04551339
View directory record Official record
Conditions
Healthy, Health Care Worker Patient Transmission, Aging
Interventions
PreserVision AREDS formulation soft gels or tablets, Multivitamin with 11mg of zinc
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional

Zinc Therapy in HIV Infected Individuals Who Abuse Drugs

NCT00149552
View directory record Official record
Conditions
HIV Infections, Substance-Related Disorders
Interventions
zinc
Dietary Supplement
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2012 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead

NCT02346188
View directory record Official record
Conditions
Lead Poisoning
Interventions
Ferrous fumarate, Zinc oxide, Placebo
Dietary Supplement
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
6 Years to 8 Years
Enrollment
602 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2001
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 10, 2026, 1:31 AM EDT
Terminated Phase 3 Interventional Results available

The CRISIS Prevention Study

NCT00395161
View directory record Official record
Conditions
Sepsis
Interventions
Metoclopramide, Zinc, Glutamine, Selenium, saline, sterile water, selenium, whey-protein
Drug · Dietary Supplement · Other
Lead sponsor
Michael Dean
Other
Eligibility
12 Months to 17 Years
Enrollment
293 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Los Angeles, California • Washington D.C., District of Columbia + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2013 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

NCT05892770
View directory record Official record
Conditions
Spasmodic Dysphonia
Interventions
Zinc gluconate supplement, Botulinum toxin type A
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF)

NCT00104494
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Zinc acetate (20mg/d)
Drug
Lead sponsor
Cystic Fibrosis Foundation
Other
Eligibility
8 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2015 · Synced Sep 10, 2026, 1:31 AM EDT
Completed Phase 1 Interventional Results available

The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy

NCT00696410
View directory record Official record
Conditions
Heart Failure, Cardiomyopathies
Interventions
Zinc Acetate
Drug
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 10, 2026, 1:31 AM EDT