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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Zio Clear all
Completed No phase listed Observational

THE GIRAFFE Study: Genomic Risk Markers for Atrial Fibrillation Following Extended Cardiac Rhythm Monitoring

NCT01970969
View directory record Official record
Conditions
Patients With Symptoms of Cardiac Arrhythmia at Risk for Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older
Enrollment
928 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 5, 2026, 8:57 AM EDT
Completed No phase listed Observational

Study Watch AF Detection At Home

NCT04546763
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Study Watch, Zio XT
Device
Lead sponsor
Verily Life Sciences LLC
Industry
Eligibility
22 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
5
States / cities
San Diego, California • Lakewood, Colorado • Southfield, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Not applicable Interventional

Pediatric Adhesion and New Dermal Approach Study

NCT07118124
View directory record Official record
Conditions
Syncope, Pediatric, Congenital Athymia, Congenital Heart Disease, Arrhythmia, Arrhythmia in Children
Interventions
Zio monitor
Device
Lead sponsor
iRhythm Technologies, Inc.
Industry
Eligibility
1 Year to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boise, Idaho • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 5, 2026, 8:57 AM EDT
Recruiting No phase listed Observational

Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF

NCT07122947
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Apple Watch: AFib History, Zio Patch
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
22 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
St Louis, Missouri • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 5, 2026, 8:57 AM EDT
Not listed Not applicable Interventional

Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease

NCT05442203
View directory record Official record
Conditions
Atrial Fibrillation, Structural Heart Disease
Interventions
Zio Patch Monitor, Echocardiogram
Device
Lead sponsor
Tempus AI
Industry
Eligibility
40 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Grand Rapids, Michigan • Cincinnati, Ohio • Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 5, 2026, 8:57 AM EDT
Withdrawn No phase listed Observational

Verily Watch Cardio (AF and ECG) Study

NCT06041373
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Verily Watch Cardio, iRhythm Zio monitor, Schiller CARDIOVIT FT-1
Device
Lead sponsor
Verily Life Sciences LLC
Industry
Eligibility
22 Years and older
Timeline
2023 – 2024
U.S. locations
3
States / cities
Lakewood, Colorado • Southfield, Michigan • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 5, 2026, 8:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome

NCT06953778
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Zio XT® Patch
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
24,060 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2033
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 5, 2026, 8:57 AM EDT
Terminated No phase listed Observational

Correlating Noninvasive Cardiovascular Measures to Left Ventricular End Diastolic Pressure in Heart Failure

NCT02406820
View directory record Official record
Conditions
Heart Failure
Interventions
Non-invasive hemodynamic monitoring (CVInsight™ [CVI])
Device
Lead sponsor
Intelomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Not applicable Interventional Results available

Holter Versus Zio Patch Electrocardiographic Monitoring in Children

NCT03309956
View directory record Official record
Conditions
Arrhythmias, Cardiac, Heart Block
Interventions
Holter Monitor, Zio Patch
Device
Lead sponsor
Columbia University
Other
Eligibility
Up to 21 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 5, 2026, 8:57 AM EDT
Completed No phase listed Observational

Extended ECG Monitoring in HCM Patients

NCT04056715
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy, Nonsustained Ventricular Tachycardia, Ventricular Tachycardia, Atrial Fibrillation, Arrhythmia
Interventions
Zio XT
Device
Lead sponsor
iRhythm Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation Study: Extended Wear Performance of the Zio Monitor - SHASTA II

NCT07205367
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Zio Monitor
Device
Lead sponsor
iRhythm Technologies, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
San Francisco, California • Deerfield, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 5, 2026, 8:57 AM EDT
Completed No phase listed Observational

Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial

NCT02952781
View directory record Official record
Conditions
Syncope, Presyncope, Atrial Fibrillation, Supraventricular Tachycardia
Interventions
EKG Patch monitors (Zio and Carnation)
Device
Lead sponsor
EvergreenHealth
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Not applicable Interventional Results available

mHealth Screening to Prevent Strokes

NCT02506244
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
iRhythm ZIO XT Patch, Wristband by Amiigo
Device
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
55 Years and older
Enrollment
6,135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 5, 2026, 8:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Screening for Atrial Fibrillation in Elderly Women Older Than 70 Years

NCT05444335
View directory record Official record
Conditions
Atrial Fibrillation New Onset
Interventions
Wearable cardiac monitor -Zio patch
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
70 Years to 100 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 5, 2026, 8:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

True Continuous ECG Monitoring (TCEM Study)

NCT01559246
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Not listed
Lead sponsor
iRhythm Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 5, 2026, 8:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Heart Rhythm Twins Study

NCT05866731
View directory record Official record
Conditions
Premature Atrial Complex, Premature Ventricular Contraction
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 5, 2026, 8:57 AM EDT
Not listed No phase listed Observational

Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial

NCT02031484
View directory record Official record
Conditions
Syncope, Presyncope, Palpitations, Atrial Fibrillation, Supraventricular Tachycardia
Interventions
Not listed
Lead sponsor
Bardy Diagnostics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Chicago, Illinois • Iowa City, Iowa • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 5, 2026, 8:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Comparative Efficacy of the Zio Patch vs Implantable Loop Recorder in Atrial Fibrillation

NCT02954380
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Zio
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2017 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Women's Health Initiative Silent Atrial Fibrillation Recording Study

NCT05366803
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Physical Activity
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
65 Years to 100 Years · Female only
Enrollment
1,257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 5, 2026, 8:57 AM EDT
Not listed Phase 2 Interventional

A Phase-II Trial of ZIO 101 in Advanced Hepatocellular Carcinoma

NCT00423306
View directory record Official record
Conditions
HEPATOCELLULAR CARCINOMA
Interventions
Darinaparsin
Drug
Lead sponsor
Alaunos Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
6
States / cities
Miami, Florida • Atlanta, Georgia • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Sep 5, 2026, 8:57 AM EDT
Completed Phase 4 Interventional

A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke

NCT04126486
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Zio®XT Monitor
Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
70 Years and older
Enrollment
11,931 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
176
States / cities
Birmingham, Alabama • Guntersville, Alabama • Montgomery, Alabama + 141 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Sep 5, 2026, 8:57 AM EDT