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ClinicalTrials.gov public records Last synced Nov 4, 2026, 12:14 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: aDBS Clear all

Conditions: Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6
Interventions: Deep Brain Stimulation; Device
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 89 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Parkinson Disease
Interventions: Activa PC+S Neurostimulator; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Parkinson's Disease (PD)
Interventions: adaptive DBS (aDBS); Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 45 Years to 75 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Parkinson Disease
Interventions: Adaptive DBS; Device
Lead sponsor: MedtronicNeuro; Industry
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 7
States / cities: San Francisco, California • Stanford, California • Gainesville, Florida + 4 more

Conditions: Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6
Interventions: Deep Brain Stimulation (DBS); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 89 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Parkinson Disease
Interventions: Open Loop DBS, Adaptive (Closed Loop) DBS, Intermittent Open Loop DBS; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: Obsessive-Compulsive Disorder
Interventions: Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period; Device · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 21 Years to 70 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas

Conditions: Parkinson Disease
Interventions: aDBS; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 20 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: PD - Parkinson's Disease
Interventions: Medtronic Percept Deep Brain Stimulation (cDBS), Medtronic Percept Deep Brain Stimulation (daytime aDBS), Medtronic Percept Deep Brain Stimulation (nighttime aDBS); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: San Francisco, California

Conditions: PD - Parkinson's Disease
Interventions: Medtronic Percept Deep Brain Stimulation (adaptive DBS), Medtronic Percept Deep Brain Stimulation (cDBS); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 25 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Parkinson Disease
Interventions: The LFP Beta aDBS System; Device
Lead sponsor: MedtronicNeuro; Industry
Eligibility: 22 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Palo Alto, California • Pittsburgh, Pennsylvania

Conditions: Obsessive-Compulsive Disorder
Interventions: Summit RC+S System, One Month Blinded Discontinuation Period:; Device · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 21 Years to 70 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas

Conditions: PARKINSON DISEASE (Disorder)
Interventions: aDBS-Extended (Medtronic Percept™), aDBS-Standard (Medtronic Percept™), Continuous DBS (cDBS) - Active Control (Medtronic Percept™); Device
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Davis, California

Conditions: Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Interventions: Deep Brain Stimulation; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 22 Years to 75 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Obsessive-Compulsive Disorder
Interventions: Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:; Device · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas

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Interposed Nucleus aDBS for Ataxia

Neural and Kinematic Features of Freezing of Gait for Adaptive Neurostimulation

Investigating Basal Ganglia-Cortical Physiology During Sleep and Its Modulation by Adaptive Deep Brain Stimulation in Parkinson Disease

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease

Deep Brain Stimulation for Spinocerebellar Ataxia

Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback

Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator

LFP Beta aDBS Feasibility Study

Development of Adaptive Deep Brain Stimulation for OCD

Optimizing Adaptive DBS for Parkinson's Disease

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder