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ClinicalTrials.gov public records Last synced Oct 29, 2026, 8:51 PM EDT

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Showing 553–576 of 1,536 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ablation Clear all
Recruiting Phase 1 Interventional

A Study of Pembrolizumab and Ablation (Cryoablation or Histotripsy) in People With Breast Cancer

NCT06246968
View directory record Official record
Conditions
Metastatic Breast Cancer, Breast Cancer, Breast Cancer Stage IV, Triple Negative Breast Cancer, Triple Negative Breast Neoplasms, Metastatic Triple-Negative Breast Carcinoma, Locally Advanced Breast Cancer, Locally Advanced Triple-Negative Breast Carcinoma
Interventions
Pembrolizumab, Cryoablation, Histotripsy
Drug · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional

Radiofrequency For Chronic Knee Pain Post-Arthroplasty

NCT02931435
View directory record Official record
Conditions
Chronic Knee Pain, Osteoarthritis, Knee
Interventions
Nerve Block with Radiofrequency Ablation, Nerve Block with Sham Radiofrequency Ablation
Procedure
Lead sponsor
Randall Brewer, MD, CPI
Other
Eligibility
50 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 29, 2026, 8:51 PM EDT
Enrolling by invitation Not applicable Interventional

Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms

NCT07619417
View directory record Official record
Conditions
Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor
Interventions
Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas, PEF-ablation of pancreatic cyst
Other · Procedure · Device
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional

Cryotherapy for Malignant Dysphagia in Patients With Advanced Esophageal Cancer

NCT02606396
View directory record Official record
Conditions
Esophageal Adenocarcinoma
Interventions
Cryotherapy, Esophagogastroduodenoscopy (EGD), Endoscopic ultrasound (EUS)
Procedure
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional

Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors

NCT03372720
View directory record Official record
Conditions
Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma, Vaginal Carcinoma, Vaginal Dryness, Vulvar Carcinoma
Interventions
Laser Therapy, Questionnaire Administration, Sham Intervention
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
4
States / cities
Baltimore, Maryland • Rochester, Minnesota • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional Results available

Nerve Ablation by Cooled Radiofrequency Compared to Corticosteroid Injection for Management of Knee Pain

NCT02343003
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Cooled Radiofrequency, Corticosteroid injection
Device · Drug
Lead sponsor
Halyard Health
Industry
Eligibility
21 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
11
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Santa Monica, California + 8 more
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional Results available

Hybrid Ablation Plus Medical Therapy for Persistent Atrial Fibrillation

NCT04190186
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Insertable Cardiac Monitor
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Ypsilanti, Michigan • Tupelo, Mississippi • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 29, 2026, 8:51 PM EDT
Withdrawn Not applicable Interventional

Noninvasive Cardiac Radioablation for Ventricular Tachycardia Refractory to Medication and Catheter Ablation

NCT04757688
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Cardiac radioablation (CRA)
Radiation
Lead sponsor
John Stahl
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional Results available

A CLinical Study to Evaluate the Safety And Effectiveness of the CeRene DevIce to Treat HeavY Menstrual Bleeding

NCT02842736
View directory record Official record
Conditions
Menorrhagia
Interventions
Cerene(R) Cryotherapy Device
Device
Lead sponsor
Channel Medsystems
Industry
Eligibility
25 Years to 50 Years · Female only
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
9
States / cities
Arlington Heights, Illinois • Naperville, Illinois • Fort Wayne, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Phase 3 Interventional Results available

A Study Exploring Two Treatment Strategies in Patients With Atrial Fibrillation Who Undergo Catheter Ablation Therapy

NCT01729871
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
rivaroxaban, uninterrupted vitamin K antagonist (VKA)
Drug
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
24
States / cities
Beverly Hills, California • Los Angeles, California • Sacramento, California + 21 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 29, 2026, 8:51 PM EDT
Withdrawn Not applicable Interventional

Magnetic Resonance Thermal Image Guided Laser Interstitial Thermal Therapy in Treating Patients With Breast Cancer

NCT01791998
View directory record Official record
Conditions
Ductal Breast Carcinoma in Situ, Invasive Ductal Breast Carcinoma, Stage IA Breast Cancer, Stage IB Breast Cancer
Interventions
magnetic resonance thermal imaging, laser interstitial thermal therapy
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Oct 29, 2026, 8:51 PM EDT
Recruiting Phase 1 Interventional

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

NCT07090148
View directory record Official record
Conditions
Prostate Cancer Patients, Non-castrate Prostate Cancer, Recurrent Prostate Cancer, Oligometastatic Prostate Cancer (OMPC)
Interventions
pTVG-HP DNA vaccine, Anti-PD-1 monoclonal antibody
Biological · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Male only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Terminated Not applicable Interventional Results available

CONcomitant eValuation of Epicor Left atRial Therapy for AF

NCT00519194
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Epicor LP Cardiac Ablation System, Surgical ablation of permanent AF
Device · Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
15
States / cities
Fresno, California • Bradenton, Florida • Pensacola, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transvaginal Radiofrequency Ablation for Overactive Bladder

NCT06458556
View directory record Official record
Conditions
Overactive Bladder
Interventions
Treatment with Morpheus
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years to 85 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Corona del Mar, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional

SERF VT Ablation Early Feasibility Study (EFS)

NCT03628534
View directory record Official record
Conditions
Ventricular Tachycardia, Arrythmia, Heart Diseases, Cardiovascular Diseases
Interventions
Saline Enhanced Radiofrequency (SERF) ablation
Device
Lead sponsor
Thermedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Maywood, Illinois • Rochester, Minnesota • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 29, 2026, 8:51 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

NCT03651804
View directory record Official record
Conditions
Vertebral Compression Fracture, Facet Joint Pain
Interventions
Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids
Procedure · Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 29, 2026, 8:51 PM EDT
Not listed Not applicable Interventional

Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain

NCT04803149
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Cooled Radiofrequency, Conventional Radiofrequency
Device
Lead sponsor
Avanos Medical
Other
Eligibility
21 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
10
States / cities
Washington D.C., District of Columbia • Bloomington, Illinois • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 29, 2026, 8:51 PM EDT
Withdrawn Not applicable Interventional

Endocardial Vs Epicardial Ablation for Recurrent Paroxysmal AF

NCT04506814
View directory record Official record
Conditions
Recurrent Paroxysmal Atrial Fibrillation Despite Prior Pulmonary Vein Isolation
Interventions
Endocardial PVI, Epicardial Posterior Wall Isolation + LAA Exclusion + Endocardial PVI
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Short Hills, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional

Electrohydraulic Versus Laser Lithotripsy for Treatment of Difficult to Remove Biliary Stones

NCT01571271
View directory record Official record
Conditions
Gall Stones
Interventions
Laser Lithotripsy, Electrohydraulic Lithotripsy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 29, 2026, 8:51 PM EDT
Not listed No phase listed Observational

Assess Differences in Pain Following Cryo and Radiofrequency Atrial Fibrillation Ablation

NCT03148392
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Sumit Verma, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pensacola, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 29, 2026, 8:51 PM EDT
Enrolling by invitation Not applicable Interventional

Use of Tracking Devices to Locate Abnormalities During Invasive Procedures

NCT00102544
View directory record Official record
Conditions
Adenocarcinoma, Prostate Neoplasms, Prostate Cancer, Renal Cell Carcinoma, Von Hippel Lindau Disease
Interventions
EM Tracking
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 120 Years
Enrollment
3,894 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Tissue Destruction and Healing in Celiac Disease

NCT05680012
View directory record Official record
Conditions
Celiac Disease
Interventions
Gluten containing snack bar
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Pasadena, California • Chicago, Illinois • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 29, 2026, 8:51 PM EDT
Completed Not applicable Interventional Results available

Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation

NCT01294267
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Circulatory Support System
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 29, 2026, 8:51 PM EDT
Terminated Not applicable Interventional

Resection Versus Microwave Ablation for Resectable Colorectal Cancer Liver Metastases

NCT02866344
View directory record Official record
Conditions
Colorectal Neoplasms, Neoplasm Metastasis, Hepatic Neoplasms
Interventions
Microwave ablation, Hepatic resection
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Oct 29, 2026, 8:51 PM EDT