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ClinicalTrials.gov public records Last synced Oct 4, 2026, 7:04 AM EDT

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Showing 145–168 of 412 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: active transcranial direct current stimulation Clear all
Not listed Not applicable Interventional

Neuromodulation of Lidocaine Cream Effect on Chronic Pain Patients

NCT03046017
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
tDCS, Lidocaine cream, Control cream
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Closed-loop System Using Transcranial Direct Current Stimulation (tDCS) for Epilepsy

NCT01415362
View directory record Official record
Conditions
Epilepsy, Seizures
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 7:04 AM EDT
Recruiting Not applicable Interventional

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

NCT05062369
View directory record Official record
Conditions
Alcohol Use Disorder, Addiction
Interventions
TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The STRENGTHEN Study

NCT06267521
View directory record Official record
Conditions
Cognitive Flexibility, Emotional Regulation
Interventions
Healthy Minds Program, Sham Meditation Didactic Material, Sham Stimulation in Lab, Stimulation in Lab, MRI Scanner
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Meditation for Pain After Total Knee Arthroplasty

NCT05673720
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
active tDCS paired with active MBM, sham tDCS paired with sham MBM
Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia

NCT02975973
View directory record Official record
Conditions
Schizophrenia, Psychosis
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

TDCS and Cognitive Retraining to Augment Pharmacotherapy for the Treatment of Nicotine Dependence

NCT02534454
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Active Retraining, Sham Retraining, Active transcranial direct current stimulation (TDCS), Sham transcranial direct current stimulation (TDCS), Nicotine Replacement Therapy (Habitrol)
Behavioral · Device · Drug
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Effects of tDCS Combined With CBI on Postsurgical Pain

NCT04199780
View directory record Official record
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02330315
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Optimized tDCS for Fibromyalgia: Targeting the Endogenous Pain Control System

NCT03371225
View directory record Official record
Conditions
Fibromyalgia
Interventions
Active tDCS, Active Exercise, Sham tDCS, Sham Exercise
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic

NCT02128919
View directory record Official record
Conditions
Schizophrenia, Cognition, Cigarette Smoking
Interventions
tDCS
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

tDCS and Inhibitory Control in PTSD

NCT06100731
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
tDCS
Device
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Oct 4, 2026, 7:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Direct Current Stimulation (tDCS) as a Treatment for Acute Fear

NCT02410954
View directory record Official record
Conditions
Fear
Interventions
NeuroConn Direct Current stimulator Multiple Channel -4
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Oct 4, 2026, 7:04 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Investigating Motor Cortex Processing for Pain Modulation

NCT01404039
View directory record Official record
Conditions
Motor Activity
Interventions
Motor Learning, Somatosensory Learning, Observational Task, Mental Imagery, transcranial direct current stimulation
Behavioral · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification

NCT04348812
View directory record Official record
Conditions
Anxiety, Stress
Interventions
ABMT, Transcranial direct current stimulation
Behavioral · Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 45 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task

NCT03309072
View directory record Official record
Conditions
Healthy Adults
Interventions
tDCS, sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Primary Progressive Aphasia

NCT02928848
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy

NCT03272906
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-language therapy
Device · Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 4, 2026, 7:04 AM EDT
Recruiting Not applicable Interventional

tDCS and Urge in BFRBs

NCT07019571
View directory record Official record
Conditions
Repetitive Compulsive Behavior
Interventions
Wireless Multichannel Transcranial Current Stimulator (tDCS), Cue exposure, Boredom induction
Device · Behavioral
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Stimulating the Brain to Improve Self-Awareness

NCT03370341
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
active anodal tDCS, sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 55 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Home-based tDCS for Prevention of Suicidal Ideation

NCT05280756
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Home-based transcranial direct current stimulation (tDCS), Sham home-based transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study

NCT02512393
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Cognitive Training and tDCS for Children With FASD

NCT03361293
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders
Interventions
Active tDCS, Cognitive training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 16 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 4, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Neurostimulation for Cognitive Enhancement in Alzheimer's Disease

NCT04404153
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver active tDCS., tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver sham tDCS.
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 4, 2026, 7:04 AM EDT