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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: air insufflation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

RCT of Air Insufflation Versus Water Infusion Colonoscopy

NCT00785889
View directory record Official record
Conditions
Colorectal Cancer
Interventions
water infusion colonoscopy
Procedure
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
45 Years to 75 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2008 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient

NCT03671837
View directory record Official record
Conditions
Apneic; Oxygenation
Interventions
Oxygen, Air
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Sep 28, 2026, 5:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT00920751
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Water infusion, Air insufflation
Procedure
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
50 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2009 · Synced Sep 28, 2026, 5:02 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparision of Air Versus CO2 for Distention During Sigmoidoscopy

NCT00771290
View directory record Official record
Conditions
Colorectal Surgery
Interventions
Air insufflation with standard endoscopy unit, CO2 insufflation for colonoscopy (special CO2 insufflation unit)
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy

NCT01954862
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., CO2 insufflation, Water Immersion/CO2, Water Exchange/CO2, Water Immersion/AI, Water Exchange/AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury

NCT00448045
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Manual and mechanical assisted cough, Incentive spirometry
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Sep 28, 2026, 5:02 PM EDT
Completed No phase listed Observational

Trans Nasal Insufflation for the Treatment of Snoring

NCT00832026
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Trans Nasal Insufflation (TNI) [nasal canula]
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)

NCT01764165
View directory record Official record
Conditions
COPD
Interventions
Oxygen, High flow of room air
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Sep 28, 2026, 5:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

NCT03566615
View directory record Official record
Conditions
Colonoscopy, Polyp of Colon
Interventions
CAP-straight, CAP-daisy, water
Device · Other
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Mather, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT01383252
View directory record Official record
Conditions
Colon Polyp
Interventions
Water infusion in lieu of air insufflation, Air method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Sep 28, 2026, 5:02 PM EDT
Withdrawn Not applicable Interventional

Transoral Gastric Volume Reduction as an Intervention for Weight Management

NCT02578836
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Fogel Gastroplasty
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Sep 28, 2026, 5:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System

NCT05448300
View directory record Official record
Conditions
Colon Adenoma, Colonoscopy
Interventions
Colonoscopy with water exchange or air insufflation methods
Device
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting

NCT01729416
View directory record Official record
Conditions
Tubular Adenoma, Colon Cancer, Hyperplastic Polyp
Interventions
Water Exchange Colonoscopy, Air Colonoscopy
Other
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Elk Grove, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 28, 2026, 5:02 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison Air Versus Carbon Dioxide Insufflation in Single Balloon Anterograde Enteroscopy

NCT03811522
View directory record Official record
Conditions
Carbon Dioxide Insufflation, Anterograde Single Balloon Enteroscopy
Interventions
carbon dioxide insufflation, Air insufflation
Other
Lead sponsor
North Eastern Ohio Gastroenterology and Endoscopy center
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Warren, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange

NCT01894191
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, Water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
651 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

NCT01607255
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant

NCT04541667
View directory record Official record
Conditions
Endoscopy
Interventions
Air, Carbon Dioxide
Other
Lead sponsor
University of Nebraska
Other
Eligibility
6 Months to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 28, 2026, 5:02 PM EDT
Recruiting Not applicable Interventional

Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery

NCT05838300
View directory record Official record
Conditions
Bariatric Surgery
Interventions
Warm humidified CO2, Dry CO2
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 28, 2026, 5:02 PM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening

NCT01780818
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 28, 2026, 5:02 PM EDT