Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 10, 2026, 5:53 PM EDT

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Showing 1–24 of 1,583 matching trials from the live ClinicalTrials.gov search.
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Conditions
Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
Interventions
Concurrent Treatment with Prolonged Exposure (COPE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Esophageal Adenocarcinoma
Interventions
Carboplatin, 3 Dimensional Conformal Radiation Therapy, Propranolol, Intensity Modulated Radiation Therapy, Paclitaxel
Drug · Radiation
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Bipolar Disorder
Interventions
lithium, valproate, bupropion, paroxetine, lamotrigine, risperidone, inositol, tranylcypromine, Cognitive Behavioral Therapy, Family-focused Therapy, Interpersonal and Social Rhythms Therapy
Drug · Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
15 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
11
States / cities
Stanford, California • Denver, Colorado • Boston, Massachusetts + 8 more
Completed Not applicable Interventional Accepts healthy volunteers

Michigan SPARC Trial

NCT04861792
Conditions
Alcohol, Drinking, Alcohol Use Disorder (AUD)
Interventions
Michigan SPARC Quality Improvement Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
9,590 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Mental Health
Interventions
Not listed
Lead sponsor
Pearson/Clinical Assessment
Industry
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
5
States / cities
Roseville, California • Denver, Colorado • Rockford, Illinois + 2 more
Conditions
Alcohol Use Disorder, Hiv, Tobacco Use Disorder
Interventions
Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Completed No phase listed Observational Accepts healthy volunteers

Brain Functional Connectivity in Alcohol Use Disorder

NCT02877849
Conditions
Alcohol Use Disorder
Interventions
MRI: Brain Imaging data collection
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Alcohol Use Disorder, Alcohol-associated Liver Disease
Interventions
Implementation Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Alcohol Craving
Interventions
Not listed
Lead sponsor
Boston University
Other
Eligibility
21 Years to 70 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional

Young Women's CoOp Study

NCT01224184
Conditions
HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions
Young Women's CoOp, Staying Healthy and Eating Well
Behavioral
Lead sponsor
RTI International
Other
Eligibility
16 Years to 19 Years · Female only
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Durham, North Carolina • Research Triangle Park, North Carolina
Conditions
Autism Spectrum Disorder
Interventions
Propranolol, Placebo, Magnetic Resonance Imaging (MRI)
Drug · Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
7 Years to 24 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions
Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 24 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Columbus, Ohio
Conditions
Alcohol Dependence
Interventions
Valproate, Naltrexone
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Iowa City, Iowa • Houston, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Approach-Avoidance and Alcohol Challenge Study in PTSD

NCT06002633
Conditions
Post-Traumatic Stress Disorder, Alcohol Drinking
Interventions
Alcohol, Placebo
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Austin, Texas
Conditions
Posttraumatic Stress Disorders
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic/Myeloproliferative Diseases
Interventions
busulfan, cyclophosphamide, cyclosporine, methotrexate, tacrolimus, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation
Drug · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
Up to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2003
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Alcohol Use Disorder
Interventions
Brexpiprazole, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
CBT Decoupling, CBT Anxiety Reduction, CBT Combined
Interventions
De-coupling, Anxiety Reduction, Combined
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Alcohol Dependence, Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Alcoholism
Interventions
Motivational Enhancement Therapy, Cognitive Behavioral Therapy, FC Assessment, IB Assessment
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
New Brunswick, New Jersey
Completed Not applicable Interventional

Alcohol Drinking as a Vital Sign

NCT01135654
Conditions
Unhealthy Drinking, Alcohol Dependence
Interventions
Training & Tech Support for Delivery of Alcohol Screening, Brief Intervention, and Referral To Treatment
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
639,613 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Oakland, California
Conditions
Alcohol-related Disorders, Post-traumatic Stress Disorder
Interventions
Couple-Based Treatment for Alcohol Use Disorders and PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
Interventions
SUCCEEDS Program, Living a Healthy College Lifestyle
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 24 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
College Park, Maryland