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ClinicalTrials.gov public records Last synced Oct 24, 2026, 3:30 PM EDT

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Showing 1–24 of 346 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: antioxidants Clear all
Completed Phase 1 Interventional

Physiological Effects of Grape Seed Extract in Diastolic Heart Failure

NCT01185067
View directory record Official record
Conditions
Diastolic Heart Failure, Hypertensive Heart Disease, Heart Failure With Preserved Ejection Fraction, Hypertension, Oxidative Stress
Interventions
grape seed extract (MegaNatural BP, Polyphenolics, Inc.)
Drug
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Phase 2 Interventional

Antioxidant Therapy in Lean and Obese Asthmatics

NCT01317563
View directory record Official record
Conditions
Asthma
Interventions
Vitamins A, E, C & Selenium, Placebo
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 25 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Phase 1Phase 2 Interventional

IdB 1016 Treatment for Hepatitis C Disease

NCT00055445
View directory record Official record
Conditions
Hepatitis C, Chronic
Interventions
IdB 1016
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Phase 2Phase 3 Interventional

A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-Angioplasty Blood Vessel Re-Closure (Restenosis) in Stented Vessels.

NCT00055510
View directory record Official record
Conditions
Graft Occlusion, Vascular, Coronary Restenosis, Atherosclerosis
Interventions
BO-653
Drug
Lead sponsor
Chugai Pharma USA
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
29
States / cities
Phoenix, Arizona • Tucson, Arizona • Burlingame, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Consumption of Pecan-enriched Meal

NCT04849962
View directory record Official record
Conditions
Healthy
Interventions
Control, Pecan
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 24, 2026, 3:30 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteers

NCT06982508
View directory record Official record
Conditions
Antioxidant Absorption
Interventions
Obicetrapib 10mg, Placebo
Drug
Lead sponsor
NewAmsterdam Pharma
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami Gardens, Florida
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Highly Processed Foods and Vascular Health

NCT05628350
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
No UPF controlled diet, High UPF controlled diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 24, 2026, 3:30 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

NCT01550510
View directory record Official record
Conditions
Stage IV Colorectal Cancer
Interventions
Ascorbic Acid, Irinotecan
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 24, 2026, 3:30 PM EDT
Active, not recruiting Phase 2 Interventional

Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas.

NCT04175301
View directory record Official record
Conditions
Malignant Glioma
Interventions
Hydrogen, Placebo oral tablet
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 24, 2026, 3:30 PM EDT
Suspended Phase 2 Interventional

Ascorbate in Myelodysplastic Syndrome

NCT07283900
View directory record Official record
Conditions
Myelodysplastic Syndromes
Interventions
High-dose ascorbate, Azacitidine
Drug
Lead sponsor
Prajwal Dhakal
Other
Eligibility
18 Years to 99 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional

Pomegranate and Hemodialysis Pilot Trial

NCT01562340
View directory record Official record
Conditions
End Stage Renal Disease, Cardiovascular Disease, Inflammation
Interventions
Pomegranate juice, Pomegranate fruit extract
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming

NCT04065035
View directory record Official record
Conditions
Photodamaged Skin, Skin Care
Interventions
Topical Body Firming Moisturizer, Body Cleanser, Sunscreen, Placebo Moisturizer
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
40 Years to 60 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2019 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Obesity, Inflammation and Oxidative Stress

NCT01028976
View directory record Official record
Conditions
C-reactive Protein, Inflammation, Obesity, Oxidative Stress
Interventions
Vitamin C (ascorbic acid), Placebo tablet
Dietary Supplement
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Practicality of Intermittent Fasting and Its Effect on Markers of Aging and Oxidative Stress

NCT02132091
View directory record Official record
Conditions
Aging, Metabolism
Interventions
Intermittent Fasting, 400 IU Vitamin E, 1000 mg Vitamin C
Other · Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
19 Years to 30 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Results available

The Effects of an Antioxidant Formulation on Ocular Blood Flow

NCT01930487
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
dietary supplement with antioxidants, Placebo
Dietary Supplement
Lead sponsor
ScienceBased Health
Industry
Eligibility
30 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Oct 24, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rapid Effects of a Biofield Patch on Antioxidant Status and Cellular Energy

NCT07314359
View directory record Official record
Conditions
Antioxidant Status
Interventions
Active dermal patch, Placebo dermal patch
Other
Lead sponsor
Natural Immune Systems Inc
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Klamath Falls, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional

Dietary Intervention in Persons With Metabolic Syndrome

NCT03836651
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Dietary Antioxidant (V8® Low Sodium 100% vegetable juice), Control group
Other
Lead sponsor
Martha Biddle
Other
Eligibility
21 Years to 90 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of a Nutraceutical Supplement With Standardized Botanicals in Peri-menopausal and Menopausal Women With Thinning Hair

NCT04048031
View directory record Official record
Conditions
Hair Thinning
Interventions
Nutrafol Supplement Capsules, Placebo Capsules
Dietary Supplement · Other
Lead sponsor
Ablon Skin Institute Research Center
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Manhattan Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)

NCT01457612
View directory record Official record
Conditions
Insulin Resistance, Nutritional Disease, Metabolic Disease
Interventions
Strawberry, Placebo1, Placebo2
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease

NCT00090402
View directory record Official record
Conditions
Alzheimer's Disease, Oxidative Stress, Dementia, Hyperlipidemia, Inflammation
Interventions
Fish Oil, Lipoic Acid, Fish Oil Placebo, Lipoic Acid Placebo
Dietary Supplement · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
55 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 24, 2026, 3:30 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study

NCT03617302
View directory record Official record
Conditions
Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension, Cognitive Decline
Interventions
Experimental: Nitrate-containing, Placebo: Nitrate-depleted
Drug
Lead sponsor
Gary L. Pierce, PhD
Other
Eligibility
50 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 24, 2026, 3:30 PM EDT
Terminated Phase 3 Interventional

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)

NCT00609180
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
Minimal (Trophic) Feeding, Full Feeding, Omega-3 Fatty Acids and Antioxidant Supplements, Placebo
Behavioral · Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
13 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
41
States / cities
Fresno, California • Sacramento, California • San Francisco, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Oct 24, 2026, 3:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Function and Oxidative Stress in Emergency Medical Responders

NCT06985394
View directory record Official record
Conditions
Cardiovascular Function in EMTs
Interventions
Antioxidant cocktail, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 24, 2026, 3:30 PM EDT
Recruiting Phase 2 Interventional

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

NCT06930638
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Antioxidant Supplement
Device · Dietary Supplement
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 24, 2026, 3:30 PM EDT