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Conditions: Drug Toxicity Psychotropic Agents Psychostimulants
Interventions: Ryanodex (dantrolene sodium) for injectable suspension; Drug
Lead sponsor: Eagle Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tibial Meniscus Injuries, Knee Injuries, Knee Injuries and Disorders
Interventions: Lipogems, Normal Saline; Device · Drug
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 45 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Lung Cancer, Cancer, Malignancy
Interventions: Nasal Swab, Oral Swab, Stool Collection, Microbiome analysis, DNA Banking, Skin Swab; Procedure · Other · Genetic
Lead sponsor: Taher Abu Hejleh; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Topical Antisepsis
Interventions: Chlorhexidine gluconate, ChloraPrep One Step, Sterile saline; Drug
Lead sponsor: C. R. Bard; Industry
Eligibility: 16 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Bozeman, Montana

Conditions: Cystic Fibrosis
Interventions: Inhaled Vancomycin, Placebo (Sterile Water), Rifampin, Trimethoprim/Sulfamethoxazole (TMP/SMX), Doxycycline, Mupirocin Intranasal Creme, 4% chlorhexidine gluconate liquid skin cleanser; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 12 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Cleveland, Ohio

Conditions: Surgical Bleeding
Interventions: Raplixa, Gelfoam, Rescue treatment; Drug · Device
Lead sponsor: Mallinckrodt; Industry
Eligibility: Up to 17 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 13
States / cities: Phoenix, Arizona • Los Angeles, California • Sacramento, California + 10 more

Conditions: Chronic Rhinosinusitis, Nasal Polyps
Interventions: Triamcinolone-impregnated CMC foam, Propel Stent; Drug · Device
Lead sponsor: Marina Boruk; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Colon Polyps, Colorectal Cancer, Inflammatory Bowel Disease (IBD)
Interventions: Colon KCC Heptapeptide; Biological
Lead sponsor: Danielle Kim Turgeon; Other
Eligibility: 18 Years to 100 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Gender Dysphoria
Interventions: Polyethylene Glycol 3350; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Stress Disorders, Post-Traumatic
Interventions: Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS); Procedure · Behavioral · Drug + 1 more
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Dental Caries
Interventions: Silver Diamine Fluoride 38%, Group 2 (Placebo); Device
Lead sponsor: Justine Kolker; Other
Eligibility: 21 Years to 64 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Hematuria, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Interventions: PuraStat; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: Male only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Topical Antisepsis
Interventions: CHG 2% w/v & IPA 70% v/v, swabstick (3 @ once)., CHG 2% w/v & IPA 70% v/v swab applied sequentially, Aqueous CHG 4% w/v applied according to mfr's directions, Sterile swabstick with sterile water (3 @ once), Sterile swabstick with sterile water (one-at-a-time); Drug · Other
Lead sponsor: C. R. Bard; Industry
Eligibility: 16 Years and older
Enrollment: 335 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Sterling, Virginia

Conditions: Dentine Hypersensitivity
Interventions: 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water; Drug · Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Venous Leg Ulcer, Diabetic Foot Ulcer
Interventions: EscharEx (EX-02 formulation); Drug
Lead sponsor: MediWound Ltd; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Tamarac, Florida • Las Vegas, Nevada • Chapel Hill, North Carolina

Conditions: Adverse Events
Interventions: Irrisept, Standard of Care; Device
Lead sponsor: Irrimax Corporation; Industry
Eligibility: Not listed
Enrollment: 592 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 17
States / cities: Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more

Conditions: Vulvar Lichen Sclerosus
Interventions: StrataMGT, Placebo; Drug
Lead sponsor: Andrew T. Goldstein, MD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Tampa, Florida • New York, New York

Conditions: Perioral Wrinkles
Interventions: Poly-L-Lactic Acid, Microneedling; Drug · Device
Lead sponsor: Skincare Physicians of Chestnut Hill; Other
Eligibility: 40 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Bladder Cancer, Urinary Tract Infection
Interventions: Irrisept® Antimicrobial Wound Lavage; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Skin Texture
Interventions: microneedling RF treatment, PLLA, Sterile Water as control; Device · Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Infection, Enterocolitis, Necrotizing, Ventilator-associated Pneumonia
Interventions: oropharyngeal mother's milk, oropharyngeal sterile water; Other
Lead sponsor: Endeavor Health; Other
Eligibility: 1 Day to 4 Days
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 5
States / cities: Miami, Florida • Evanston, Illinois • Park Ridge, Illinois + 2 more

Conditions: Pilonidal Disease
Interventions: Irrisept (0.05% chlorhexidine gluconate), Normal Saline; Device · Other
Lead sponsor: Yosef Nasseri, MD; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Ventilator-associated Pneumonia
Interventions: Biotene OralBalance® gel, Sterile Water moisten cotton tipped applicator; Drug · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 7 Days and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: Winston-Salem, North Carolina

Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: YJ001 for Spray Use, Placebo of YJ001 for Spray Use; Drug
Lead sponsor: Zhejiang Hanmai Pharmaceutical Technology Co., Ltd.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Fredericksburg, Texas

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Efficacy and Safety Study of Ryanodex as Adjuvant Treatment in Subjects With Psychostimulant Drug-Induced Toxicity (PDIT)

Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military

Microbiome in Lung Cancer and Other Malignancies

Preoperative Skin Preparation Evaluation

Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)

Topical Raplixa for Surgical Bleeding in Children

Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposis

Study of KCC Peptide Application in the Colon

Polyethylene-glycol Assisted Nerve Repair in Phalloplasty

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

Silver Diamine Fluoride Pilot Study (SDF)

RADA16 for Aquablation Day Case

Test for Pre Operative Skin Preparations

Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity

A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers

Retrospective Independent Safety Review of Closed Irrisept Study

StrataMGT in the Reduction of Vulvar Lichen Sclerosus (LS) Symptoms

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation

Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)

Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease

Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates

MAD Study to Assess the Safety, Tolerability, PKs and Efficacy of YJ001 for Spray Use in Patients With DPNP