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Showing 1–24 of 83 matching trials from the live ClinicalTrials.gov search.
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Withdrawn Not applicable Interventional

Assessment of Cerebral Microvascular Circulation

NCT02179840
View directory record Official record
Conditions
Cerebral Microvascular Circulation
Interventions
Mechanical ventilation adjustment
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional Results available

Pilot Study on Pairing Sedation Strategies and Weaning

NCT02219659
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Phase 1Phase 2 Interventional

Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial

NCT01242462
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Conventional Pressure Controlled SIMV, Mid-frequency Ventilation
Procedure · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 7 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 1, 2014 · Synced Sep 27, 2026, 1:21 PM EDT
Withdrawn Phase 2 Interventional

Effects of Nitric Oxide on the Endothelium During Hemolysis.

NCT03748082
View directory record Official record
Conditions
Endothelial Dysfunction, Hemolysis Intravascular, Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Nitric Oxide, Reactive Hyperemia Index, Endothelial Cells Collection
Drug · Diagnostic Test · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional

The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions

NCT04514354
View directory record Official record
Conditions
Cardiovascular Diseases, Post-Exercise Hypotension
Interventions
GEST
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 27, 2026, 1:21 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Gas Kinetics and Metabolism in Anesthesia During Non Steady State

NCT00225381
View directory record Official record
Conditions
Anesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries, Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)
Interventions
connection of measuring device to anesthesia circuit, drawing of blood sample through an arterial line, placed according to clinical criteria by primary anesthesia team, changing operating room bed position (head down and up position), adding PEEP during anesthesia, placement of esophageal Doppler for cardiac output measurements, Humidity sensor, A mixing chamber (bymixer), Pneumotachometer cuvette, Mass spectrometer sampling port
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 27, 2026, 1:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Accuracy of Pulse Oximeters With Profound Hypoxia

NCT03710980
View directory record Official record
Conditions
Oximetry
Interventions
Oximeter
Device
Lead sponsor
Hancock Medical, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional Results available

Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia

NCT03734822
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
End tidal CO2 (EtCO2), Transcutaneous CO2 (TCO2), Capillary CO2 (CapCO2), Arterial blood gas (ABG)
Other · Device · Diagnostic Test
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Sep 27, 2026, 1:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Diagnostic Device for the Assessment of Pulpal Blood Flow

NCT03578549
View directory record Official record
Conditions
Dental Pulp Test
Interventions
Pulse Oximetry
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Phase 3 Interventional

Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy

NCT00200148
View directory record Official record
Conditions
Pancreaticoduodenectomy, Hepatectomy
Interventions
Normovolemic Hemodilution (ANH), Standard of care
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SpO2 Accuracy Comparison of Smart Sock V. 2 SpO2 to Arterial Blood CO-Oximetry

NCT03630016
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse oximetry with Owlet BabySat v1.0 sensor
Diagnostic Test
Lead sponsor
Owlet Baby Care, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Sep 27, 2026, 1:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Newborn Screening for Critical Congenital Heart Disease

NCT01765205
View directory record Official record
Conditions
Congenital Cardiovascular Malformation
Interventions
Pulse Oximetry using the INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter
Device
Lead sponsor
University of Florida
Other
Eligibility
12 Hours to 2 Weeks
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2014 · Synced Sep 27, 2026, 1:21 PM EDT
Withdrawn Not applicable Interventional

Sleep Ventilation for Patients With Advanced Hypercapnic COPD

NCT04210050
View directory record Official record
Conditions
COPD
Interventions
Home noninvasive nocturnal ventilation with Breas VIVO 50 home ventilator or newer model as available, Breas Medical., Arterial blood gas (ABG) and serum bicarbonate level, Overnight home oximetry and transcutaneous CO2 monitoring
Device · Diagnostic Test
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 27, 2026, 1:21 PM EDT
Active, not recruiting Not applicable Interventional

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

NCT06501118
View directory record Official record
Conditions
Respiratory Failure, Acute Hypoxemic Respiratory Failure, Acute Hypoxic Respiratory Failure, Hypoxemia, Hypoxia, Hypoxic Respiratory Failure
Interventions
Education, Epic notification alert
Other · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 27, 2026, 1:21 PM EDT
Terminated Not applicable Interventional

Recovery After Dialysis-Requiring Acute Kidney Injury

NCT03305549
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Conservative dialysis strategy, TIW dialysis strategy
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Accuracy of an Integrated Vital Sign Measurement Platform

NCT03589716
View directory record Official record
Conditions
Multimorbidity
Interventions
Vital Moto Mod, Welch Allyn Connex Spot Vital Signs Monitor, Capnostream 20 Portable Bedside Capnograph, Welch Allyn 767 Mobile Aneroid Sphygmomanometerand 3M Littmann Master Classic II Teaching Stethoscope, Scifit 1000R cycle ergometer
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Sep 27, 2026, 1:21 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation

NCT06063148
View directory record Official record
Conditions
Skin Pigment, Pulse Oximetry
Interventions
Enrolled Participant
Device
Lead sponsor
University of California, Davis
Other
Eligibility
Up to 10 Days
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Sacramento, California • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 27, 2026, 1:21 PM EDT
Terminated No phase listed Observational

Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients

NCT00744614
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Interventions
Capnography
Procedure
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2010 · Synced Sep 27, 2026, 1:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pulse Oximeter Hypoxia

NCT04562584
View directory record Official record
Conditions
Oximetry
Interventions
MyHomeDoc
Device
Lead sponsor
MyHomeDoc Ltd.
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2020 · Synced Sep 27, 2026, 1:21 PM EDT
Withdrawn No phase listed Observational

Pulse Oximetry Accuracy by Skin Color

NCT05692453
View directory record Official record
Conditions
Surgery
Interventions
Arterial blood gas with co-oximetry
Diagnostic Test
Lead sponsor
Brittany Willer
Other
Eligibility
2 Years to 9 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 27, 2026, 1:21 PM EDT
Not listed Not applicable Interventional

Intraoperative Oxygen Concentration and Neurocognition After Cardiac Surgery

NCT02591589
View directory record Official record
Conditions
Hyperoxia, Normoxic, Delirium
Interventions
Normoxic oxygenation, Hyperoxic oxygenation
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Sep 27, 2026, 1:21 PM EDT
Not listed Not applicable Interventional

Evaluation of Clinical Tool to Improve Adherence to Ventilator Management at UM

NCT05661695
View directory record Official record
Conditions
Respiratory Therapy
Interventions
RT Assistant
Device
Lead sponsor
Convergent Engineering, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 27, 2026, 1:21 PM EDT
Completed No phase listed Observational

Verification of Pulse Oximetry in Neonatal Population

NCT00751439
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
1 Day to 30 Days
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Sep 27, 2026, 1:21 PM EDT
Terminated Not applicable Interventional Results available

Validation of Mixed Venous Blood Oxygen Saturation Obtained With a Novel Mathematical Equation

NCT00783952
View directory record Official record
Conditions
Mixed Venous Oxygen Saturation, Tissue Oxygenation
Interventions
Cerebral/Somatic Tissue Oximeter device, Pulmonary artery catheter
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 27, 2026, 1:21 PM EDT