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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:03 AM EDT

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Showing 97–120 of 371 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ascorbic acid Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Treatment of Non-Anemic Iron Deficiency in Pregnancy

NCT05423249
View directory record Official record
Conditions
Non-anemic Iron Deficiency
Interventions
Ferrous sulfate, Prenatal, Docusate Sodium, Ascorbic Acid 500Mg Tab, Placebo
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
3
States / cities
Bohemia, New York • Commack, New York • East Setauket, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits

NCT05523115
View directory record Official record
Conditions
Anxiety, Stress, Memory Deficits, Cortisol Overproduction
Interventions
Heights Smart Supplement
Dietary Supplement
Lead sponsor
Heights
Industry
Eligibility
21 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 20, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Function and Oxidative Stress in Emergency Medical Responders

NCT06985394
View directory record Official record
Conditions
Cardiovascular Function in EMTs
Interventions
Antioxidant cocktail, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Vitamin C Supplement for Lumbar Spine Surgery

NCT03918694
View directory record Official record
Conditions
Lumbar Spine Surgery
Interventions
Vitamin C, Placebo
Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Study Evaluating Quality of Life Parameters Following Use of Emergen-C

NCT06654089
View directory record Official record
Conditions
Dietary Supplements
Interventions
Emergen-C Core Super Orange Powder, Placebo
Dietary Supplement
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 64 Years
Enrollment
299 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Completed No phase listed Observational

VCSIP Follow-up Study

NCT03203603
View directory record Official record
Conditions
Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
Interventions
No active intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Months to 4 Years
Enrollment
242 participants
Timeline
2017 – 2024
U.S. locations
2
States / cities
Indianapolis, Indiana • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Vitamin C on Iron Absorption

NCT00570895
View directory record Official record
Conditions
Iron Deficiency
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 8 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2020 · Synced Oct 20, 2026, 1:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pediatric COVID Outcomes Study (PECOS)

NCT04830852
View directory record Official record
Conditions
Covid19, MIS-C Associated With COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children, SARS-CoV2 Infection
Interventions
Not listed
Lead sponsor
Children's National Research Institute
Other
Eligibility
0 Years to 21 Years
Enrollment
1,097 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Treatment for COVID-19 in High-Risk Adult Outpatients

NCT04354428
View directory record Official record
Conditions
COVID-19, SARS-CoV-2
Interventions
Ascorbic Acid, Hydroxychloroquine Sulfate, Azithromycin, Folic Acid, Lopinavir 200 MG / Ritonavir 50 MG [Kaletra]
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
6
States / cities
Chicago, Illinois • New Orleans, Louisiana • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Clinical Research Study to Evaluate Stain Removal and Whitening Improvement

NCT07870018
View directory record Official record
Conditions
Tooth Whitening, Tooth Discoloration
Interventions
Vitamin C toothpaste, Matching placebo
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

NCT06376110
View directory record Official record
Conditions
Acne
Interventions
Topical Antioxidant Serum, AviClear Laser
Drug · Device
Lead sponsor
Austin Institute for Clinical Research
Network
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pflugerville, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Mitochondrial Cocktail for Gulf War Illness

NCT02804828
View directory record Official record
Conditions
Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorders
Interventions
Individualized mitochondrial cocktail, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
48 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Oct 20, 2026, 1:03 AM EDT
Terminated Phase 2 Interventional Results available

Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery

NCT03334409
View directory record Official record
Conditions
Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v7, Unresectable Renal Cell Carcinoma
Interventions
Ascorbic Acid, Pazopanib Hydrochloride
Drug
Lead sponsor
Academic and Community Cancer Research United
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
5
States / cities
Peoria, Illinois • Urbana, Illinois • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Melatonin and Vitamin C on COVID-19

NCT04530539
View directory record Official record
Conditions
Covid19, SARS-CoV Infection
Interventions
Vitamin C, melatonin, Placebo, Symptom Survey
Dietary Supplement · Other
Lead sponsor
Lancaster General Hospital
Other
Eligibility
50 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced Oct 20, 2026, 1:03 AM EDT
Active, not recruiting Not applicable Interventional

Functional Snack Foods With Safflower Oil and Soy in Postmenopausal Women Having Metabolic Syndrome

NCT02199054
View directory record Official record
Conditions
Metabolic Syndrome, Overweight
Interventions
wheat-safflower oil pretzels, soy-safflower oil pretzels, control wheat pretzels
Other
Lead sponsor
Ohio State University
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate Formation From Ascorbic Acid

NCT04603898
View directory record Official record
Conditions
Kidney Stone
Interventions
Low Oxalate Diet, Carbon-13 Ascorbic Acid Oral Load
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"

NCT01073332
View directory record Official record
Conditions
Excessive Physical Exercise, Unspecified
Interventions
Arginine antioxidant supplements, Placebo
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 8, 2015 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Vitamin C and Cardiovascular Risk

NCT00534014
View directory record Official record
Conditions
Atherosclerosis, Type 2 Diabetes
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 20, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers

NCT07220265
View directory record Official record
Conditions
Carrier of Phenylketonuria, Healthy
Interventions
Phenylalanine (Phe), Placebo
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition Interventions to Support the Immune System in Response to Stress

NCT02053506
View directory record Official record
Conditions
Mitigation of Immune Function Decrements in Response to Stress
Interventions
Immune-enhancing nutritional beverage, Probiotics (BB-12), Placebo (for nutritional beverage and probiotic)
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 45 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Phase 1Phase 2 Interventional

Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma

NCT00006021
View directory record Official record
Conditions
Multiple Myeloma and Plasma Cell Neoplasm
Interventions
ascorbic acid, arsenic trioxide
Dietary Supplement · Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 120 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
4
States / cities
Miami, Florida • Miami Beach, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced Oct 20, 2026, 1:03 AM EDT
Withdrawn Not applicable Interventional

EoE Food Desensitization

NCT02881372
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
Oral food desensitization
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Phase 1 Interventional

Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women

NCT00862433
View directory record Official record
Conditions
Diabetes, Fatty Liver, Obesity, Healthy Volunteers
Interventions
Alpha tocopherol, Vitamin E, Vitamin C
Drug · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 55 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 1:03 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective

NCT01754987
View directory record Official record
Conditions
Metastatic Hepatocellular Carcinoma, Advanced Liver Cancer
Interventions
Ascorbic Acid + Sorafenib, Sorafenib
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 20, 2026, 1:03 AM EDT