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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:22 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 751 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: behavioral weight loss Clear all

Conditions: Obesity, Overweight
Interventions: Weight Loss Phase, Continued CBT, reduced energy density education, continued use of meal replacements; Behavioral
Lead sponsor: Drexel University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 238 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Overweight and Obesity
Interventions: Diet and Exercise Tracking; Behavioral
Lead sponsor: Prostasis, LLC, dba Tonum Health; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Timeline: 2025
U.S. locations: 1
States / cities: West Palm Beach, Florida

Conditions: Adolescent Overweight, Adolescent Obesity, Sleep, Eating Behaviors, Dietary Intake
Interventions: Lifestyle Modification and Sleep Intervention; Behavioral
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 14 Years to 18 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Non-Alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic, Obesity
Interventions: Mindfulness Based Stress Reduction (MBSR); Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: PreDiabetes, Prediabetic State
Interventions: Diabetes Prevention Program (DPP); Behavioral
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Migraine, Obesity
Interventions: Behavioral Weight Loss Intervention, Migraine Education; Behavioral · Other
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Autosomal Dominant Polycystic Kidney
Interventions: Daily caloric restriction, Standard advice control; Behavioral · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Weight Loss
Interventions: RCT1, RCT2, RCT3; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 64 Years
Enrollment: 2,395 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 3
States / cities: Swansea, Illinois • Research Triangle Park, North Carolina • Fairborn, Ohio

Conditions: Arthroplasty, Overweight and Obesity
Interventions: PACE Weight Loss program, Chronic Disease Self-Management; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: Not listed
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Obesity, Cardiovascular Disease, High Blood Pressure
Interventions: In Person, At Home; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 45 Years to 65 Years · Female only
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Drug Discontinuation, Substance Use Disorders, Eating Behavior Changes, Tirzepatide
Interventions: Discontinuation and Reinitiation of Tirzepatide; Other
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity, Behavior, Health, Weight Loss
Interventions: Noom Healthy Weight; mobile behavior change program for weight loss., Matched Control; Behavioral · Other
Lead sponsor: Noom Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Commack, New York

Conditions: Endometrial Cancer
Interventions: behavioral dietary intervention, exercise intervention, counseling intervention, educational intervention, survey administration; Behavioral · Other
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obesity
Interventions: PILI Lifestyle Program; Behavioral
Lead sponsor: University of Hawaii; Other
Eligibility: 13 Years and older
Enrollment: 335 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Honolulu, Hawaii

Conditions: Obesity
Interventions: Shape Up Rhode Island, Shape Up Rhode Island + Professional Coach + Incentives, Shape Up Rhode Island + Peer Coach + Incentives; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1
Interventions: Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination); Behavioral · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Breast Cancer
Interventions: Weight Loss Dietary Pattern; Other
Lead sponsor: Colorado State University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 259 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Obesity and Type 2 Diabetes
Interventions: Behavioral Skill Training, Meal Provisioning; Behavioral · Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Obesity, Overweight and Obesity, Quality of Life, Health Behavior
Interventions: Noom Healthy Weight; Behavioral
Lead sponsor: Noom Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 370 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity, Malignant Neoplasm
Interventions: Interview, Media Intervention, Questionnaire Administration, Scale Device, Telephone-Based Intervention, Text Message; Other · Behavioral
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 13 Years to 30 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity, Metabolic Diseases
Interventions: Dietary supplement for weight loss, Education and counseling for weight loss; Drug · Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Obesity
Interventions: Standard weight loss intervention, Standard weight loss intervention plus technology, Technology only; Behavioral
Lead sponsor: John M. Jakicic, PhD; Other
Eligibility: 18 Years to 55 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity, Weight Loss
Interventions: Component 1: Calorie Goal Attainment, Component 2: Diet Quality, Component 3: Physical Activity Goal Attainment, Component 4: Goal Setting; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Cardiovascular Disease, Obesity
Interventions: Behavioral weight loss intervention, Diet Plus Moderate Exercise, Diet Plus High Exercise; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 55 Years
Enrollment: 383 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Weight Loss Maintenance in Primary Care

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

Improving Sleep, Decision-Making, and Eating in Adolescents With Obesity

Effects of Mindfulness Based Stress Reduction Intervention in Patients With Non-alcoholic Fatty Liver Disease

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

Behavioral Weight Loss as a Treatment for Migraine in Obese Women

Renal Oxygen Consumption, Insulin Sensitivity, and Daily Caloric Restriction in ADPKD

Weight Management Demonstration Project: HEALTH

Healthy Living After Knee Replacement

Healthy Bodies, Healthy Hearts: A Physical Activity Intervention Trial

Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation

Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention

Exercise and Healthy Diet or Standard Care in Patients in Remission From Stage I or Stage II Endometrial Cancer

Partnerships to Improve Lifestyle Interventions (PILI) 'Ohana Dissemination Project

State-wide Health Approach to Increase Reach and Effectiveness: Study 3

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

Diet Composition, Weight Control, and Breast Carcinogenesis

Investigating Metabolic and Psychological Adaptations in a Clinical Trial

Improving Quality of Life in Men and Women With Overweight or Obesity

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome

The Comparison of a Technology-Based System and an In-Person Behavioral Weight Loss Intervention

Optimizing Self-Monitoring Feedback for the Treatment of Obesity

Effect of Exercise and Weight Loss on Cardiovascular Health