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ClinicalTrials.gov public records Last synced Nov 5, 2026, 4:32 AM EST

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Showing 1–24 of 395 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: botulinum type a Clear all

Conditions: Chronic Post Traumatic Headache
Interventions: OnabotulinumtoxinA; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Overactive Bladder
Interventions: onaBoNT-A, Oxybutynin ER; Drug
Lead sponsor: Christopher Patrick Smith; Other
Eligibility: 18 Years to 80 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Muscle Spasticity, Stroke
Interventions: onabotulinumtoxinA, placebo (normal saline); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Glabellar Lines
Interventions: Formulation A: OnabotulinumtoxinA, Formulation B: OnabotulinumtoxinA, Formulation C: OnabotulinumtoxinA; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 5
States / cities: Glendale, Arizona • Coral Gables, Florida • New Orleans, Louisiana + 2 more

Conditions: Blepharospasm
Interventions: incobotulinumtoxinA (Xeomin), Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions: NT 201, Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 603 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 15
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Downey, California + 11 more

Conditions: Nervous System Disorders
Interventions: Botulinum toxin type A, Placebo; Biological · Drug
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 15
States / cities: Downey, California • Fairfield, Connecticut • Boca Raton, Florida + 10 more

Conditions: Urinary Incontinence
Interventions: OnabotulinumtoxinA; Biological
Lead sponsor: Allergan; Industry
Eligibility: 5 Years to 17 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • Orange, California + 11 more

Conditions: Masticatory Myofascial Pain Syndrome
Interventions: Onabotulinumtoxin A, Placebo; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: BTA, Placebo (normal saline); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Multiple Sclerosis, Lower Urinary Tract Symptoms, Neurogenic Bladder, Detrusor, Overactive, Urge Incontinence
Interventions: Intra-detrusor injection of Onabotulinumtoxin-A; Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Spinal Cord Injuries
Interventions: Bladder chemodenervation (Botox), Bladder Sham (Saline) Injection Procedure; Drug · Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Glabellar Frown Lines
Interventions: Botulinum Toxin A, Placebo, Botulinum Toxin A - Open Label; Drug
Lead sponsor: Croma-Pharma GmbH; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 7
States / cities: Encinitas, California • Aventura, Florida • Sarasota, Florida + 4 more

Conditions: Anxiety Disorder Social, Anxiety
Interventions: botulinum toxin A, Placebo; Drug · Other
Lead sponsor: Daniel Lieberman; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Glabellar Frown Lines
Interventions: PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA; Drug
Lead sponsor: Evolus, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Lateral Canthal Lines, Crow's Feet
Interventions: botulinum toxin, Type A, Vehicle; Biological
Lead sponsor: Eirion Therapeutics Inc.; Industry
Eligibility: 25 Years to 65 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 5
States / cities: Miami, Florida • Pinellas Park, Florida • Louisville, Kentucky + 2 more

Conditions: Stiff Knee Gait, Brain Injuries
Interventions: placebo, botulinum toxin A (BTX-A); Drug
Lead sponsor: Mary Free Bed Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Overactive Bladder, Detrusor Instability, Detrusor Hyperreflexia
Interventions: Botulinum-A toxin, Dimethyl sulfoxide (DMSO); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Temporomandibular Joint Disorders, Bruxism, Temporomandibular Joint Dysfunction Syndrome, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint
Interventions: onabotulinumtoxinA; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Myofascial Pelvic Pain
Interventions: Intervention-Botulinum Toxin Type A, placebo; Drug
Lead sponsor: Boston Urogynecology Associates; Other
Eligibility: 18 Years and older · Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Hyperhidrosis
Interventions: Vehicle, ANT-1207; Biological
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 19
States / cities: Hialeah, Florida • Miami, Florida • Pinellas Park, Florida + 16 more

Conditions: Gingival Exposure
Interventions: Botulinum toxin type A; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Secondary Headache Disorder
Interventions: Botulinum Toxin type A; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 74 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Prostate Cancer, Lower Urinary Tract Symptoms, Radioactive Seed Implantation
Interventions: Botox injection, Saline injection; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Search by objective public record fields.

Treatment of Chronic Post-Traumatic Headache With OnabotulinumtoxinA

OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER

OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity

A Study of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Blepharospasm

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Dysport® Adult Upper Limb Spasticity

A Long-Term Extension Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity

MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain

Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects

Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder

Early BOTOX After Spinal Cord Injury

Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study II

A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder

Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines

ET-01 in Subjects With Lateral Canthal Lines, LCL-208

Efficacy of Botulinum Toxin Injections in the Rectus Femoris to Treat Stiff Knee Gait Following Acquired Brain Injury

Botulin-A Toxin Instillations and Overactive Bladder

Botox for Treatment of TMJ Disorder With Bruxism

Botulinum Toxin Type A Versus Saline Trigger Point Injections for Myofascial Pelvic Pain

Clinical Trial To Evaluate ANT-1207 In Participants With Primary Axillary Hyperhidrosis

Botox for Gummy Smile

The Effect of Botulinum Toxin A on Headache Attributed to TMD

Botulinum Toxin Injection With Prostate Brachytherapy