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ClinicalTrials.gov public records Last synced Oct 5, 2026, 1:57 AM EDT

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Showing 49–72 of 402 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: brief intervention (cognitive-behavioral therapy) Clear all
Recruiting Not applicable Interventional

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

NCT05658796
View directory record Official record
Conditions
Mood Disorders, Anxiety, Depressive Symptoms, Depression, Anxiety Disorders, Anxiety Depression
Interventions
-RxWell
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional

Cognitive and Emotion Regulation Training in MS

NCT02717429
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Mindfulness Meditation, Computerized Cognitive Training
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 59 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional

Developing Identity: An Eating Disorder Randomized Clinical Trial

NCT01517906
View directory record Official record
Conditions
Anorexia Nervosa, Bulimia Nervosa
Interventions
Identity Intervention Program, Supportive Psychotherapy for the Eating Disorders
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Results available

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

NCT04523779
View directory record Official record
Conditions
Anxiety
Interventions
Brief Cognitive Behavioral Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
New Orleans, Louisiana • Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Results available

A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease

NCT05651542
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Interventions
Comprehensive Self-Management Intervention, Control
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional

Treatment of Post-Traumatic Stress Disorder (PTSD) and Chronic Pain After Traumatic Orthopedic Injury

NCT00957164
View directory record Official record
Conditions
Chronic Pain, Post-traumatic Stress Disorder
Interventions
Brief Prolonged Exposure Protocol, Chronic Pain Management Treatment, Self-Care
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Arlington, Texas • Fort Sam Houston, Texas • Lackland Air Force Base, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2014 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Brain Stimulation on Higher-Order Cognition

NCT03814967
View directory record Official record
Conditions
Schizophrenia
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Phase 2 Interventional Results available

Oxytocin and Social Cognitive Skills Groups

NCT02918864
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Oxytocin, Social Cognitive Skills Training, Facilitated Play Therapy
Drug · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
8 Years to 11 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 5, 2026, 1:57 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression

NCT05966532
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Healthy Adult Volunteer
Interventions
Hot Cognitive Task, Cold cognitive tasks, Structural magnetic resonance imaging (sMRI), Magnetoencephalography imaging (MEG), four self-report forms per the requirement of the NIH Common Data Elements project, Four self-report measures to assess interpersonal functioning, Clinical assessments, ATHF
Behavioral · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Arlington, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Teachable Moment Brief Intervention for Suicide Attempt Survivors in an Inpatient Setting

NCT03600532
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Teachable Moment Brief Intervention (TMBI)
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 5, 2026, 1:57 AM EDT
Not yet recruiting Not applicable Interventional

Prospective Randomized Study of TPS + CBT VS TPS Alone: Readmission, Opioid Use, and Chronic Pain

NCT07783672
View directory record Official record
Conditions
Pain
Interventions
Transitional Pain Service
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-based Intervention to Prevent Chronic Pain

NCT04848428
View directory record Official record
Conditions
Pain, Postoperative, Chronic Pain, Pain Catastrophizing, Pain, Acute
Interventions
Online mindfulness-based cognitive therapy, Online standardized education
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 5, 2026, 1:57 AM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Five Factor Model Treatment for Borderline Personality Disorder

NCT04587518
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Personality-Based Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 5, 2026, 1:57 AM EDT
Recruiting Not applicable Interventional

Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

NCT06311838
View directory record Official record
Conditions
Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions
Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 24 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Recruiting Not applicable Interventional

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT

NCT05442957
View directory record Official record
Conditions
Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship, Psychosocial Impairment, Mental Health Issue
Interventions
BRIGHT, Attention Control
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
Detroit, Michigan • St Louis, Missouri • Hershey, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional

Improving Management of Breathlessness in Patients With Lung Cancer

NCT01937637
View directory record Official record
Conditions
Breathlessness, Dyspnea, Lung Cancer
Interventions
Cognitive Behavioral Intervention for Breathlessness
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2015 · Synced Oct 5, 2026, 1:57 AM EDT
Not listed Not applicable Interventional

Optimizing Daily Mindfulness Interventions Using Peer Support to Increase Well-Being in First-Year Students

NCT04828291
View directory record Official record
Conditions
OMI, OMI+, Control Group
Interventions
Benign Behavioral Interventions
Behavioral
Lead sponsor
Pitzer College
Other
Eligibility
18 Years to 30 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Claremont, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2021 · Synced Oct 5, 2026, 1:57 AM EDT
Terminated Not applicable Interventional Results available

Evaluation of a Computerized Intervention for Learning to Re-Evaluate Suicidal Thoughts

NCT04254809
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Re-Evaluating Suicidal Thoughts, Healthy Social Living
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet-based Conversational Engagement Clinical Trial

NCT02871921
View directory record Official record
Conditions
Aging, Mild Cognitive Impairment
Interventions
Conversational Engagement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
75 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 5, 2026, 1:57 AM EDT
Active, not recruiting Not applicable Interventional

Abbreviated MBCT for Depression in Older Black or African American Breast Cancer Survivors

NCT06336538
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Female, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, Mild Depression, Moderate Depression
Interventions
MBCT
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional

Co-Designing a Virtual Reality Intervention to Enhance Skill Development

NCT07186543
View directory record Official record
Conditions
Suicide
Interventions
Cognitive Behavioral Therapy (CBT) Worksheets, Practice Experiences for School Reintegration (PrESR)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Ukrainian Student Problem Solving Project

NCT06064578
View directory record Official record
Conditions
Trauma, Anxiety, Depression, Child Behavior
Interventions
Project SOLVE
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
10 Years to 18 Years
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Oct 5, 2026, 1:57 AM EDT
Completed Not applicable Interventional Results available

Symptom Management for YA Cancer Survivors

NCT04035447
View directory record Official record
Conditions
Cancer, Young Adult, Pain, Psychological Distress, Fatigue, Breast Cancer, Melanoma, Hematologic Cancer, Germ Cell Tumor, Endocrine Cancer
Interventions
Behavioral Symptom Management for Young Adult Cancer Survivors
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2025 · Synced Oct 5, 2026, 1:57 AM EDT