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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.

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Filters: Intervention: changes in ventilator settings Clear all

Conditions: Focus is on Healthy Subjects
Interventions: Reusable, Transparent, and Reconfigurable N95-Equivalent Respirator Masks: Design, Fabrication, and Clinical Trials for Enhanced Adoption; Device
Lead sponsor: SEEUS95 Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Respiratory Distress Syndrome
Interventions: changes in ventilator settings; Other
Lead sponsor: Respironics, California, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Respiratory Distress Syndrome
Interventions: ASV, Lung Protective Ventilation; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Respiratory Failure, Dyspnea During Mechanical Ventilation, Mechanical Ventilation
Interventions: Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow, Change in PEEP, Change to PSV; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Invasive Mechanical Ventilation, Children With Medical Complexity, Home Nursing, Empowerment
Interventions: Parent-to-parent coaching; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Low Tidal Volume Ventilation, Acute Respiratory Distress Syndrome
Interventions: HLR, EHR; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sepsis
Interventions: Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples; Procedure · Drug · Device + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Mechanical Ventilation
Interventions: VentCoach, Standard of Care; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Respiratory Distress Syndrome
Interventions: Esophageal Catheter; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: High flow nasal cannula, Nasal CPAP; Procedure
Lead sponsor: Sharp HealthCare; Other
Eligibility: 23 Weeks to 28 Weeks
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Healthy
Interventions: Filtration of all PM and VOC's, Filtration of VOC's; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Robotic Surgery, Post Operative Pulmonary Complications
Interventions: Low Intensity Mechanical Ventilation; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
Interventions: Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP), Diaphragm Ultrasound, Maximal Inspiratory Pressure; Other · Diagnostic Test
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 30 Days to 18 Years
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Ventilator-Induced Lung Injury, Sepsis Syndrome, Mechanical Ventilation Complication
Interventions: PEEP (positive end-expiratory pressure) - maximum, PEEP (positive end-expiratory pressure) - standard; Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Bronchial Asthma, Status Asthmaticus
Interventions: Standard of Care therapies, NiPPV Therapy, Routine Respiratory Care; Procedure · Device
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 2 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

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Reusable, Transparent, and Reconfigurable N95-equivalent Respirator Masks: Design, Fabrication, and Trials for Enhanced Adoption

Noninvasive Estimation of Work of Breathing

Adaptive Support Ventilation in Acute Respiratory Distress Syndrome

Mechanical Ventilator Adjustments and Patient Dyspnea

Parent-to-parent Coaching While Awaiting Hospital Discharge With a Child With a Ventilator

Pulmonary Vascular Effects of Respiratory Rate & Carbon Dioxide

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

Mechanical Power-Guided Lung Protective Ventilation (VentCoach) in Acute Hypoxemic and/or Hypercapnic Respiratory Failure

Assessment of Occult Lung Stress During Lung Protective Mechanical Ventilation

Physiological Changes With High-Flow Nasal Cannula

Efficacy of Respiratory Protection Against the Effects of Wood Smoke Exposure in Young Healthy Adults

Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study

Real-time Effort Driven VENTilator Management

CT for Personalized Mechanical Ventilation

NiPPV in the Treatment of Acute Asthma Exacerbations