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ClinicalTrials.gov public records Last synced Oct 9, 2026, 6:15 AM EDT

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Showing 49–72 of 135 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: cognitive behavioral therapy for smoking cessation Clear all
Completed Not applicable Interventional

Motivational Interviewing Compared to Psychoeducation for Smoking Precontemplators With SMI

NCT01982617
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Motivational Interviewing, Psychoeducation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 4 Interventional

Bupropion as an Adjunct to the Nicotine Patch Plus CBT

NCT00142831
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Pharmacotherapies for Smoking Cessation
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
20 Years to 65 Years
Enrollment
293 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS)

NCT01842334
View directory record Official record
Conditions
Nicotine Dependence, Smoking Cessation
Interventions
Cognitive Behavioral Therapy, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Sense2Stop:Mobile Sensor Data to Knowledge

NCT03184389
View directory record Official record
Conditions
Stress, Smoking Cessation, Overeating
Interventions
Prompt to use smartphone apps for stress management
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Yoga for Women Attempting Smoking Cessation

NCT00492310
View directory record Official record
Conditions
Smoking
Interventions
yoga, cognitive therapy, wellness
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2010 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Smoking Cessation for Smokers With Sleep Problems

NCT01277887
View directory record Official record
Conditions
Nicotine Dependence, Cigarette Smoking, Insomnia
Interventions
Cognitive-Behavioral Counseling, Smoking Cessation Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Heart Rate Variability Biofeedback for Smoking Cessation

NCT03972137
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch
Behavioral · Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Behavioral Training on Physiological Responses to Smoking Cues, Affect and Cortisol

NCT01362101
View directory record Official record
Conditions
Smokers
Interventions
Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
Behavioral
Lead sponsor
A. Eden Evins
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2013 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing Genetic Education for Smoking Cessation

NCT01186016
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Genetic Education Session, Nutrition Education Session
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare, Inc.

NCT02601521
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Disorder
Interventions
Internal tobacco coach, External tobacco coach
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 3 Interventional Results available

A Randomized Trial of Medi-Cal Beneficiaries Calling the California Smokers' Helpline

NCT01502306
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone counseling, Nicotine patches, Incentive
Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
3,816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional Results available

Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence

NCT01292642
View directory record Official record
Conditions
Cannabis Dependence, Nicotine Dependence
Interventions
Cognitive Behavioral Therapy, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2013 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Trial of Web-Delivered Acceptance Therapy for Smoking Cessation (WebQuit)

NCT01812278
View directory record Official record
Conditions
Smoking
Interventions
ACT, CBT
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
2,637 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Not yet recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Embedding Comprehensive Smoking Cessation Programs Into Community Clinics

NCT04717544
View directory record Official record
Conditions
Smoking Cessation
Interventions
Intervention Arm
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
406 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Withdrawn Not applicable Interventional

Cognitive and Emotional Skills to Aid Smoking Cessation

NCT03148652
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Enhanced Intervention Condition
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07398404
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Acceptance and Commitment Therapy for Tobacco Cessation Among Psychiatric Partial Hospital Patients

NCT03911960
View directory record Official record
Conditions
Tobacco Smoking, Psychiatric Disorder, Psychiatric Hospitalization
Interventions
Acceptance and Commitment Therapy, Enhanced Usual Care
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 25, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Early Phase 1 Interventional

Smoking Cessation Treatment for Head & Neck Cancer Patients

NCT01098955
View directory record Official record
Conditions
Head and Neck Cancer, Smoking Cessation
Interventions
Acceptance and Commitment Therapy, Motivational and Behavioral Counseling, Varenicline
Behavioral · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder

NCT02750904
View directory record Official record
Conditions
Smoking, Bipolar Disorder
Interventions
Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Palo Alto, California • Denver, Colorado • Bedford, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

NCT04501016
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Tailored behavioral counseling, Tobacco cessation pharmacotherapy
Behavioral · Drug
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RITCH: Reducing Disparities in Tobacco Cessation Outcomes

NCT02785536
View directory record Official record
Conditions
Smoking Cessation
Interventions
RITCh Treatment, Standard Treatment
Behavioral
Lead sponsor
The City College of New York
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2016 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

HCV-Smoking Cessation Study

NCT05466981
View directory record Official record
Conditions
Hepatitis C, Smoking Cessation
Interventions
Cognitive Behavioral Counseling
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1 Interventional

Smoking Cessation for Depression and Anxiety Treatment

NCT02002858
View directory record Official record
Conditions
Smoking, Anxiety Disorders, Depression Disorders
Interventions
Nicotine Patch, Depression and Anxiety Smoking Cessation Treatment, Educational-Support Psychotherapy
Drug · Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 9, 2026, 6:15 AM EDT