Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 13, 2026, 3:51 PM EDT

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Showing 145–168 of 403 matching trials from the live ClinicalTrials.gov search.
Recruiting No phase listed Observational Accepts healthy volunteers

Collection of Samples USOPTIVAL Study

NCT04792684
Conditions
Colorectal Cancer (CRC), Advanced Adenomas (AA)
Interventions
Optimization of Plasma Circulating Free-DNA (cfDNA) Marker Panel
Diagnostic Test
Lead sponsor
Universal Diagnostics
Industry
Eligibility
45 Years to 84 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
16
States / cities
Chula Vista, California • San Diego, California • Walnut Creek, California + 11 more
Conditions
Colorectal Cancer
Interventions
CRC screening reminder, CRC Reminder & Short message, CRC Reminder and Navigation Program, CRC Reminder & CRC education
Behavioral
Lead sponsor
Yale University
Other
Eligibility
50 Years to 74 Years
Enrollment
3,127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting No phase listed Observational Accepts healthy volunteers

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

NCT06059963
Conditions
Colorectal Cancer, Advanced Adenocarcinoma
Interventions
Signal-C™
Device
Lead sponsor
Universal Diagnostics
Industry
Eligibility
45 Years to 84 Years
Enrollment
12,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Raonoke, Virginia
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

The Implementation of Genetic Risk for Colorectal Cancer Screening

NCT07621757
Conditions
Colorectal Cancer, Colorectal Adenoma, Colorectal Polyp
Interventions
Not listed
Lead sponsor
Endeavor Health
Other
Eligibility
45 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Colonic Neoplasms
Interventions
Control, Quantitative, Default
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 75 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Screening in a Community Health Setting

NCT03072095
Conditions
Cancer of the Colon
Interventions
Text-only, Text + Lottery
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years to 74 Years
Enrollment
281 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening

NCT00810771
Conditions
Colorectal Neoplasms
Interventions
Standard Information, Preference-tailored Information
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 78 Years
Enrollment
466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Screen to Save 2: Rural Cancer Screening Educational Intervention

NCT04414306
Conditions
Cancer, Colorectal Cancer
Interventions
Online educational video and website module
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet-Based Motivational Interviewing for Colonoscopy

NCT03595904
Conditions
Colorectal Neoplasms
Interventions
E-Motivate group, Usual Care Group
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
45 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Recruiting No phase listed Observational Accepts healthy volunteers

Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

NCT07224789
Conditions
Colorectal Cancer
Interventions
cf-circRNA assay
Diagnostic Test
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Duarte, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Colorectal Cancer Death Through Mailed Outreach Screening

NCT02584998
Conditions
Colorectal Cancer
Interventions
Mailed-FIT, Screening invitation-reminder
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 74 Years
Enrollment
782 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Engaging Black Men in Colorectal Cancer Screening

NCT05980182
Conditions
Colorectal Cancer, CRC, Behavior
Interventions
mHealth Application
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
45 Years to 74 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Colorectal Cancer
Interventions
Auto Mailing Plus Money, Auto Mailing Plus Lottery
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
50 Years to 75 Years
Enrollment
898 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Colorectal Neoplasms, Digestive System Diseases, Colonic Diseases, Colorectal Cancer
Interventions
Stool Sample Collection Kit
Device
Lead sponsor
Exact Sciences Corporation
Industry
Eligibility
40 Years to 90 Years
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
21
States / cities
Newport Beach, California • Hamden, Connecticut • Holiday, Florida + 17 more
Conditions
Lynch Syndrome, Colorectal Cancer
Interventions
LS tumor screening, Genetic testing, Genetic Counseling, Biorepository, Questionnaire
Genetic · Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3,470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
49
States / cities
Akron, Ohio • Barberton, Ohio • Batavia, Ohio + 29 more
Completed Phase 3 Interventional Accepts healthy volunteers

Assessing Repeat Fit Testing for CRC

NCT03248661
Conditions
Colo-rectal Cancer
Interventions
Now I'm Telling You
Behavioral
Lead sponsor
Richard Crosby
Other
Eligibility
30 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Completed No phase listed Observational Accepts healthy volunteers

Adherence to Minimally Invasive Testing

NCT02251782
Conditions
Colorectal Cancer
Interventions
Epi proColon Test, Fecal Immunochemical Test (FIT)
Device
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
50 Years to 76 Years
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Portland, Oregon • Danville, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Shared Decision-making and Colorectal Cancer Screening

NCT04748380
Conditions
Colorectal Cancer
Interventions
CRC decision aid pamphlet, Home Safety Pamphlet
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
75 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Colorectal Cancer Screening
Interventions
Semi-structured interviews-Patients, Semi-structured interviews-Health system
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Prevention Research Study: Eat Right, Screen Right

NCT07393906
Conditions
Colorectal Cancer Prevention
Interventions
Web-based module
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Ku Ola Project: Enhancing Health Promotion Among Native Hawaiian Men.

NCT06964633
Conditions
Health Promotion, Health
Interventions
Kūkākūkā Discussion Sessions
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older · Male only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Honolulu, Hawaii
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Economic Incentives and Cancer Health Risk Assessment

NCT03068052
Conditions
Cancer of the Colon
Interventions
No incentive, Incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years to 64 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Colorectal Cancer
Interventions
All eligible subjects will provide blood for SEPT9 biomarker testing
Other
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
50 Years and older
Enrollment
7,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
20
States / cities
Boca Raton, Florida • Miami, Florida • Atlanta, Georgia + 15 more
Completed Not applicable Interventional Accepts healthy volunteers

Addressing Colorectal Cancer in South Florida Firefighters

NCT05976282
Conditions
Colorectal Cancer, CRC
Interventions
Fecal Immunochemical Test, Septin9 Test
Other
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 65 Years
Enrollment
646 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Miami, Florida