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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Recruiting Phase 2 Interventional

Window of Opportunity in Preserving Laryngeal Function Trial

NCT07423078
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Locally Advanced Laryngeal Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma
Interventions
Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy
Drug · Radiation
Lead sponsor
Matthew Spector
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Stereotactic Radiation Therapy in Treating Patients With Liver Metastases

NCT00938457
View directory record Official record
Conditions
Unspecified Adult Solid Tumor
Interventions
stereotactic radiation therapy, implanted fiducial-based imaging, cone-beam computed tomography
Radiation · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Phase 2 Interventional

Fluoroscopy or 3-D Roadmap Imaging Software for Liver Tumor Treatment

NCT01818440
View directory record Official record
Conditions
Image-Guided Surgery
Interventions
3D Roadmap software, Fluoroscopy
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer

NCT01843673
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
computed tomography, cone-beam computed tomography, radiography, electronic portal imaging, image-guided adaptive radiation therapy
Procedure · Radiation
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional

Feasibility Study of Cone Beam Imaging for Radiation Therapy Treatment Verification

NCT00582959
View directory record Official record
Conditions
Radiation Treatment for Tumors
Interventions
Cone Beam Imaging
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2014 · Synced Sep 25, 2026, 9:25 AM EDT
Terminated Not applicable Interventional

Development of Real-time Image-guided Radiotherapy

NCT03524248
View directory record Official record
Conditions
Breast Cancer, Lung Cancer, Skin Cancer
Interventions
Image guided radiation therapy
Radiation
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional

4D CBCT and Intrafractional Imaging for the Determination of the Most Representative 4D Simulation Planning Technique for Lung SBRT Technique Patients

NCT04717804
View directory record Official record
Conditions
Cancer of Lung
Interventions
AIP CT, FB (Free-Breathing) CT
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 25, 2026, 9:25 AM EDT
Recruiting Not applicable Interventional

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

NCT05804318
View directory record Official record
Conditions
Prostate Cancer
Interventions
Daily adaptive SBRT with urethral sparing
Device
Lead sponsor
Varian, a Siemens Healthineers Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
5
States / cities
Duarte, California • Irvine, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

Using a Head and Neck Maskless Immobilization Device For Patients With Intracranial Tumors

NCT03076255
View directory record Official record
Conditions
Brain and Nervous System, Intracranial Neoplasm, Head and Neck Cancer
Interventions
Computed Tomography, Medical Device, Cone-Beam Computed Tomography
Procedure · Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 25, 2026, 9:25 AM EDT
Recruiting Early Phase 1 Interventional

Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy

NCT07436364
View directory record Official record
Conditions
Soft Tissue Sarcoma
Interventions
Definity, Contrast-Enhanced Ultrasound
Drug · Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Enrolling by invitation Not applicable Interventional

Closed Sinus Augmentation With a Calcium Phosphosilicate Putty

NCT06507709
View directory record Official record
Conditions
Dental Implant, Maxillary Sinus Floor Augmentation
Interventions
Low volume CBCT
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density

NCT04686084
View directory record Official record
Conditions
Dental Diseases
Interventions
Dual-energy computed tomography scan
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Withdrawn Not applicable Interventional

Daily Adaptive Radiation Therapy: An Individualized Approach for Stage III Lung Cancer

NCT05488626
View directory record Official record
Conditions
Stage III Non-small Cell Lung Cancer
Interventions
Adaptive Radiotherapy, Non-Adaptive Radiotherapy, Chemotherapy, Immunotherapy
Device · Drug
Lead sponsor
Varian, a Siemens Healthineers Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

A Study Using Cone Beam CT for Head and Neck Cancer

NCT01661062
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Cone Beam Computed Tomography (CT) Scan
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2016 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional

Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer

NCT05785845
View directory record Official record
Conditions
Early Stage Non-small Cell Lung Cancer, Non-small Cell Lung Cancer
Interventions
Computed tomography-guided stereotactic adaptive radiotherapy, ETHOS
Radiation · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Terminated No phase listed Observational

4D Cone Beam CT Reconstruction for Radiotherapy Via Motion Vector Optimization

NCT03551405
View directory record Official record
Conditions
Lung Cancer
Interventions
CBCT scan
Radiation
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 25, 2026, 9:25 AM EDT
Completed No phase listed Observational

Vascular CT Assessment of Structural Autograft and Allograft Healing

NCT00594776
View directory record Official record
Conditions
Bone Tumors
Interventions
Cone Beam CT Scan
Device
Lead sponsor
University of Rochester
Other
Eligibility
10 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Sep 25, 2026, 9:25 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cone Beam Computed Tomography for Breast Imaging

NCT01107860
View directory record Official record
Conditions
Breast Cancer
Interventions
Computed Tomography
Device
Lead sponsor
Koning Corporation
Industry
Eligibility
35 Years and older · Female only
Enrollment
401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation

NCT06296459
View directory record Official record
Conditions
Dental Implant
Interventions
3D R100 scanner, Conventional Radiograph
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Sep 25, 2026, 9:25 AM EDT
Recruiting Not applicable Interventional

Feasibility Study of CBCT for IGRT in Cancer Patients

NCT06681233
View directory record Official record
Conditions
Head and Neck Cancers, Breast Cancer, Thoracic Cancers, Liver Cancer, Genito Urinary Cancer, Gastrointestinal Cancers
Interventions
Comparison of HyperSight CBCT imaging to conventional CBCT imaging.
Device
Lead sponsor
Varian, a Siemens Healthineers Company
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 25, 2026, 9:25 AM EDT
Terminated Phase 2 Interventional Results available

Use of Cone Beam Kilovoltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer

NCT00358007
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
PTV Reduction
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

Assess the Feasibility of Cone Beam CT to Localize Liver Metastases Immediately Prior to Radiotherapy

NCT00600613
View directory record Official record
Conditions
Localize Liver Metastases
Interventions
cone beam imaging
Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 95 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Not applicable Interventional Results available

KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer

NCT02337465
View directory record Official record
Conditions
Adult Liver Carcinoma, Malignant Pancreatic Neoplasm, Prostate Carcinoma
Interventions
Cone-Beam Computed Tomography, 3-Dimensional Ultrasound-Guided Radiation Therapy
Device · Radiation
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Sep 25, 2026, 9:25 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cone Beam Computed Tomography for Breast Imaging

NCT00972413
View directory record Official record
Conditions
Breast Cancer
Interventions
Computed Tomography
Radiation
Lead sponsor
Koning Corporation
Industry
Eligibility
40 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2012 · Synced Sep 25, 2026, 9:25 AM EDT