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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:14 AM EDT

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Showing 1–24 of 313 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: connectivity Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse

NCT02080819
View directory record Official record
Conditions
Cocaine Dependence
Interventions
levodopa/carbidopa 400/100 BID
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Not applicable Interventional Results available

Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury

NCT03854214
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Functional Electric Stimulation cycling, Passive cycling
Device
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 27, 2026, 1:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

NCT02655978
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Magnetic Resonance Imaging
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Oct 27, 2026, 1:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements

NCT00063115
View directory record Official record
Conditions
Ideomotor Apraxia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Phase 1 Interventional

Meditative Neurofeedback for Depression

NCT06675240
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Depression Disorders
Interventions
MediNF, ShamMediNF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Terminated Not applicable Interventional

SMARTfit Training for Parkinson's Disease

NCT03921359
View directory record Official record
Conditions
Parkinson Disease, Exercise Training, Cognitive Change
Interventions
SMARTfit training, Conventional physical training
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 27, 2026, 1:14 AM EDT
Withdrawn Not applicable Interventional

Functional Connectivity and Predictors of Affective Aprosodia Intervention in Subacute Right Hemisphere Stroke

NCT04575909
View directory record Official record
Conditions
Right Hemispheric Stroke
Interventions
Aprosodia Intervention, No-Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Use of Circadian Reset Technology to Alter REM Sleep and Appetitive Control in Patients With Binge Eating Disorder

NCT06858774
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Circadian Reset Technology, VR Headset
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Not applicable Interventional Results available

Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia

NCT04309370
View directory record Official record
Conditions
Schizophrenia
Interventions
20 Hz rTMS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Oct 27, 2026, 1:14 AM EDT
Completed No phase listed Observational

Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members

NCT05183087
View directory record Official record
Conditions
Traumatic Brain Injury, Blast Injuries
Interventions
3T Connectome MRI, 7 Tesla MRI, TSPO PET, Tau PET, Cognitive and Behavioral Assessments, Blood Biomarkers
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 45 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia

NCT06389266
View directory record Official record
Conditions
Schizophrenia, Nicotine Dependence
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Mobile Health Program for Post-Preeclampsia Hypertension

NCT07599579
View directory record Official record
Conditions
Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
Interventions
Coaching application, Home-based blood pressure monitoring, WebMD
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Investigation of Cocaine Addiction Using mGluR5 PET and fMRI

NCT03471182
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Psychiatric and Cognitive Testing, Cocaine Self-adminstration, Positron Emission Tomography, Magnetic Resonance Imaging
Behavioral · Drug · Radiation + 1 more
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 27, 2026, 1:14 AM EDT
Completed No phase listed Observational

Students Education Training in Emotional Connection

NCT03680001
View directory record Official record
Conditions
Child Development, Premature Birth
Interventions
Training in Rating Emotional Connection
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 40 Years
Enrollment
54 participants
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 27, 2026, 1:14 AM EDT
Not yet recruiting Not applicable Interventional

Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)

NCT05509842
View directory record Official record
Conditions
Parkinson Disease
Interventions
rTMS
Device
Lead sponsor
University of Michigan
Other
Eligibility
45 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional

Mobile Health Program for Rural Hypertension

NCT05546931
View directory record Official record
Conditions
Hypertension,Essential, Adherence, Medication, Quality of Life
Interventions
Coaching application, WebMD, Home-based blood pressure monitoring
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

NCT05977439
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Suicidal Ideation
Interventions
Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT), Cognitive Flexibility and Emotion Regulation Tasks
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Recruiting Early Phase 1 Interventional

Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems

NCT06779188
View directory record Official record
Conditions
Aging, Balance Deficits
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham
Device
Lead sponsor
Weinberg Medical Physics LLC
Industry
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Withdrawn No phase listed Observational

Hypercapnia and Its Association With Long-term Respiratory Morbidities in Premature Infants With Chronic Lung Disease

NCT02996162
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Massimo Root Monitoring System, ISA-Infrared Sidestream Gas Analyzer
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Days to 1 Year
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 27, 2026, 1:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Transcranial Magnetic Stimulation on Memory

NCT00105118
View directory record Official record
Conditions
Healthy, Healthy Volunteer, HV
Interventions
Magstim Super Rapid Magnetic Stimulator
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 1:14 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Efficacy of Reading Intervention on the Brain Connectivity in Autism

NCT05568056
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism, Reading Problem
Interventions
Visualizing and Verbalizing for Language comprehension and Thinking
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
7 Years to 13 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Early Phase 1 Interventional

Testing a Transdiagnostic TMS Treatment Target

NCT06282146
View directory record Official record
Conditions
Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders, Mental Disorder, Anxiety Disorders, OCD, PTSD
Interventions
transcranial magnetic stimulation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health

NCT07804550
View directory record Official record
Conditions
Childhood Obesity, Evidence-Based Practice, Food Systems, Food Policy
Interventions
Catalyzing Communities, FICAS Implementation Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
3,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 27, 2026, 1:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

MRI of Glymphatic Clearance During Anesthetic Sedation

NCT02768688
View directory record Official record
Conditions
Glymphatic Flow
Interventions
Brain connectivity and physiology, Dexmedetomidine
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 27, 2026, 1:14 AM EDT