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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:37 PM EDT

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Showing 1–11 of 11 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: continuous negative external pressure Clear all
Withdrawn Not applicable Interventional

Home Study of Subjects Who Have Completed a Previous Continuous Negative External Pressure (cNEP) Clinical Trial

NCT03108417
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
continuous negative external pressure
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
22 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 20, 2026, 5:37 PM EDT
Terminated Not applicable Interventional Results available

Pilot Study of cNEP for the Treatment of Snoring

NCT02767843
View directory record Official record
Conditions
Snoring
Interventions
continuous negative external pressure (cNEP)
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 20, 2026, 5:37 PM EDT
Not listed Not applicable Interventional

Study Using Negative Pressure to Reduce Apnea

NCT04861038
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Apnea, Sleep
Interventions
aerSleep II
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
15
States / cities
Tucson, Arizona • Little Rock, Arkansas • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 20, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure

NCT05675345
View directory record Official record
Conditions
Acute Hypoxemic Respiratory Failure
Interventions
HFNC only, HFNC + CNEP10, HFNC + CNEP20, HFNC + CNEP30
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 20, 2026, 5:37 PM EDT
Terminated Not applicable Interventional Results available

Management of Complex Wounds Using a Constant Tension External Tissue Expander

NCT01171521
View directory record Official record
Conditions
Wounds and Injuries
Interventions
DermaClose Group
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 26, 2016 · Synced Oct 20, 2026, 5:37 PM EDT
Terminated No phase listed Observational

DermaClose DUKE Fasciotomy and Wound Study

NCT05330767
View directory record Official record
Conditions
Wound of Skin
Interventions
DermaClose Continuous External Tissue Expander Device, DermaClose XL Continuous External Tissue Expander Device, Conventional wound dressings
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 20, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study

NCT04718142
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
vNEP
Device
Lead sponsor
Somne, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2021 · Synced Oct 20, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Effectiveness and Safety of cNEP in Ethnic Japanese With Obstructive Sleep Apnea

NCT03375905
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
cNEP
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kaneohe, Hawaii
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Oct 20, 2026, 5:37 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery.

NCT03414762
View directory record Official record
Conditions
Cesarean Section Complications, Cesarean Wound; Dehiscence, Cesarean Wound Disruption
Interventions
PICO Negative Pressure Wound Therapy, Standard Dressing
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 20, 2026, 5:37 PM EDT
Withdrawn Not applicable Interventional

Continuous Negative External Pressure for the Treatment of Primary Snoring

NCT03372070
View directory record Official record
Conditions
Snoring
Interventions
cNEP
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 20, 2026, 5:37 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy

NCT01895062
View directory record Official record
Conditions
Airway Obstruction, Apnea, Hypopnea
Interventions
Airway Management System (AMS)
Device
Lead sponsor
5i Sciences, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 20, 2026, 5:37 PM EDT