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Showing 1–24 of 326 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: continuous positive airway pressure Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy

NCT03369197
View directory record Official record
Conditions
Hypoxia, Endoscopy, Anesthesia Morbidity
Interventions
Nasal Mask, Control: Nasal Cannula
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 25, 2026, 3:53 PM EDT
Completed No phase listed Observational

Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients

NCT01099735
View directory record Official record
Conditions
Sleep Apnea, Gastroesophageal Reflux Disease
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Pilot Study on Pairing Sedation Strategies and Weaning

NCT02219659
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

NCT03736382
View directory record Official record
Conditions
Obstructive Sleep Apnea, Spinal Cord Injuries
Interventions
Mild intermittent hypoxia, Sham protocol, Continuous positive airway pressure (CPAP)
Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 25, 2026, 3:53 PM EDT
Active, not recruiting Not applicable Interventional

Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants

NCT04413097
View directory record Official record
Conditions
IVH- Intraventricular Hemorrhage, Extreme Prematurity, Hypoxia Neonatal, Hyperoxia, Respiratory Insufficiency
Interventions
Delayed Cord Clamping with Low Oxygen concentration, Delayed Cord Clamping with High Oxygen concentration
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
22 Weeks to 28 Weeks
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Davis, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 25, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional

The Recovery in Stroke Using PAP Study

NCT04130503
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
PAP, HLE
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Phase 4 Interventional Results available

Oxygen Versus PAP for Sleep Apnea in Heart Failure

NCT01807897
View directory record Official record
Conditions
Heart Failure, Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
West Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 25, 2026, 3:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device

NCT05570747
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usability
Other
Lead sponsor
Bleep, LLC
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
3
States / cities
Asheville, North Carolina • Huntersville, North Carolina • Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure

NCT01531465
View directory record Official record
Conditions
Respiratory Insufficiency
Interventions
Pulmonary Function Testing & esophageal pressure monitoring, Pulmonary function testing and esophageal pressure
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
2 Days to 6 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Sep 25, 2026, 3:53 PM EDT
Not listed Not applicable Interventional

Peer-Driven Intervention for Sleep Apnea

NCT02056002
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usual Care, Peer-Buddy System
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 4, 2017 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Understanding the Sleep Apnea/Insomnia Interaction

NCT01824472
View directory record Official record
Conditions
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Interventions
CPAP, CBT, sham CPAP, CC
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 25, 2026, 3:53 PM EDT
Terminated Not applicable Interventional Results available

The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants

NCT02680639
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
BiPAP Synchrony ventilator
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2019 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Phase 2 Interventional

Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack

NCT00251290
View directory record Official record
Conditions
Transient Ischemic Attack, Sleep Apnea
Interventions
auto-titrating continuous positive airway pressure
Procedure
Lead sponsor
Yale University
Other
Eligibility
45 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2009 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Using Telemedicine to Improve Veteran Sleep Apnea Care

NCT01259440
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Video Teleconferencing Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2015 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Continuous Airway Pressure on the Ability to Heat and Humidify Air

NCT00338403
View directory record Official record
Conditions
Healthy
Interventions
Continuous positive airway pressure (CPAP) at -5, 0, 5 and 10 cm of water
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Sep 25, 2026, 3:53 PM EDT
Withdrawn Not applicable Interventional

Evaluating the Efficacy of CPAP Therapy for the Treatment of Fatty Liver

NCT01849081
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
CPAP, LIfestyle
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 25, 2026, 3:53 PM EDT
Terminated Not applicable Interventional

CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure

NCT03670732
View directory record Official record
Conditions
Prematurity, Respiratory Distress Syndrome, Apnea of Prematurity
Interventions
continuous positive airway pressure, nasal intermittent positive pressure ventilation
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Up to 6 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Sep 25, 2026, 3:53 PM EDT
Not listed Not applicable Interventional

The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study

NCT01121445
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
NeilMed nose and sinus irrigation
Device
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated May 11, 2010 · Synced Sep 25, 2026, 3:53 PM EDT
Not yet recruiting Not applicable Interventional

Parent Perceptions of OptiPAP Junior

NCT07837700
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD), Preterm Birth Complication, Pulmonary, CPAP
Interventions
Nasal CPAP interface: OptiPAP Junior, Nasal CPAP interface: FlexiTrunk
Device
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 30 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional

Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women

NCT04993651
View directory record Official record
Conditions
Morbid Obesity, Cesarean Delivery Affecting Fetus
Interventions
CPAP
Device
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT03349437
View directory record Official record
Conditions
COPD, Dyspnea
Interventions
Vitabreath Device, Pursed Lip Breathing
Device · Other
Lead sponsor
Philips Respironics
Industry
Eligibility
40 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Youngstown, Ohio • Jefferson Hills, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Sep 25, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway Pressure

NCT01560975
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Primary Open-angle Glaucoma
Interventions
SENSIMED Triggerfish®
Device
Lead sponsor
Sensimed AG
Industry
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Sep 25, 2026, 3:53 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating Changes in Middle Ear Pressure Caused by CPAP

NCT02882022
View directory record Official record
Conditions
Eustachian Tube Disorder
Interventions
Continuous positive airway pressure
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 25, 2026, 3:53 PM EDT
Active, not recruiting Not applicable Interventional

Sleep for Stroke Management and Recovery Trial

NCT03812653
View directory record Official record
Conditions
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
Interventions
CPAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
3,062 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
116
States / cities
Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 94 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 25, 2026, 3:53 PM EDT