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ClinicalTrials.gov public records Last synced Oct 28, 2026, 3:53 PM EDT

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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: custom orthotics Clear all
Not listed Not applicable Interventional

Efficacy of a Custom Temporary Foot Orthosis for Plantar Fasciitis Treatment

NCT01882894
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
Custom PFO, Faux orthosis
Device · Other
Lead sponsor
University of Puget Sound
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 21, 2013 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain

NCT00076453
View directory record Official record
Conditions
Osteoarthritis
Interventions
Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2011 · Synced Oct 28, 2026, 3:53 PM EDT
Completed No phase listed Observational

3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient

NCT07565636
View directory record Official record
Conditions
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Interventions
3D scanned and 3D printed wrist hand orthosis
Device
Lead sponsor
ELewis
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional

Improving Walking After a Lower Limb Injury Using a Custom Motorized Orthosis

NCT06923293
View directory record Official record
Conditions
Lower Limb Injury
Interventions
Utilization of motorized orthosis
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional

Impact of Foot Orthoses on Gait in Individuals With Ataxia

NCT07720700
View directory record Official record
Conditions
Ataxia
Interventions
Home wearing schedule
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Phase 4 Interventional

Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis

NCT03935295
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
AbobotulinumtoxinA, Placebos, Custom Thoracolumbosacral Orthosis
Drug · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
10 Years to 16 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 28, 2026, 3:53 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Iterative Design of Custom Dynamic Orthoses

NCT04800510
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Phase 2 Interventional

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

NCT03189173
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment
Device · Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 79 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

NCT06127316
View directory record Official record
Conditions
Traumatic Lower Limb Injury
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional

Case Series_Targeted Training for Trunk Control Cerebral Palsy

NCT02246751
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Targeted Training for trunk control
Device
Lead sponsor
University of Hartford
Other
Eligibility
2 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison Study of Three Standard Elbow Wrist Hand Orthoses to Limit Forearm Rotation

NCT04130425
View directory record Official record
Conditions
Healthy
Interventions
Hely & Weber MTC Fracture Brace, Thermoplastic orthosis, Delta cast orthosis
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effectiveness of Splinting After Collagenase Injection

NCT04874870
View directory record Official record
Conditions
Dupuytren Contracture, Dupuytren's Disease
Interventions
Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis
Drug · Combination Product
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nocturnal Mouth Guards, SOVA vs. Standard Acrylic Orthotic; Phase IV

NCT02340663
View directory record Official record
Conditions
Sleep Bruxism, Tooth Wear
Interventions
SOVA Bite Splint, Michigan Bite Splint
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.

NCT02693834
View directory record Official record
Conditions
Stroke, CVA, Hemiplegia, Hemiparesis, Foot Drop
Interventions
Posterior Leaf spring AFO, Double adjustable AFO
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke

NCT03215771
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke
Interventions
MyoPro Motion-G, Motor Learning-Based Therapy
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

A Trial of Custom Foot Orthoses for the Treatment of Plantar Heel Pain

NCT00765843
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
orthoses
Device
Lead sponsor
Rosalind Franklin University of Medicine and Science
Other
Eligibility
18 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Chicago, Illinois • North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Orthotic Dose Response Study

NCT02629731
View directory record Official record
Conditions
Ankle Osteoarthritis, Flat Foot or Pes Planus
Interventions
custom orthoses with varying degrees of hindfoot posting
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Forearm Rotation Orthosis for Stroke

NCT01987414
View directory record Official record
Conditions
Stroke
Interventions
occupational therapy task-oriented approach, Forearm rotation orthosis, No treatment
Behavioral · Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional

Home-based Under Mattress Monitor for OSA

NCT07186725
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
Interventions
Under-mattress monitor, level 3 Home Sleep Apnea Test, Mandibular Advancement Device (MAD)
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation

NCT05917678
View directory record Official record
Conditions
Deformational Plagiocephaly, Deformational Posterior Plagiocephaly, Brachycephaly, Torticollis, Congenital Muscular Torticollis
Interventions
Repositioning Therapy, Cranial Remolding Orthosis
Other · Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
2 Months to 3 Months
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Not applicable Interventional Results available

Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis

NCT00124462
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Realigning knee brace and custom orthodic, Non realigning knee brace and flat orthodic
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2017 · Synced Oct 28, 2026, 3:53 PM EDT
Not listed Not applicable Interventional

Novel Splinting Technique Using 3D Models

NCT05351060
View directory record Official record
Conditions
Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse, Rheumatoid Arthritis
Interventions
Custom Fabricated Splint
Other
Lead sponsor
Giovanna Fichera
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Oct 28, 2026, 3:53 PM EDT
Completed Phase 1Phase 2 Interventional

Duration of Spinal Manipulation Effects as Influenced by Orthotics

NCT01704807
View directory record Official record
Conditions
Low Back Pain
Interventions
foot orthotics, Sham foot orthotic
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Oct 28, 2026, 3:53 PM EDT