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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:18 PM EDT

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Showing 145–168 of 220 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: dental implant Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Soft and Hard Tissue Changes Around Implants

NCT05769673
View directory record Official record
Conditions
Edentulous Alveolar Ridge
Interventions
Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional

Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth

NCT06354634
View directory record Official record
Conditions
Dental Caries, Tooth Decay
Interventions
Resin polymer (NuSmile Bioflx) crown, Stainless steel crown
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
3 Years to 7 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 10, 2026, 1:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 10, 2026, 1:18 PM EDT
Withdrawn No phase listed Observational

Early Loading of Dental Implants: A Prospective Study in the Mandibular First Molar Area

NCT02836964
View directory record Official record
Conditions
Dental Implants
Interventions
Crown placement
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 10, 2026, 1:18 PM EDT
Completed No phase listed Observational

Ultrasound Crestal Bone Topography of Edentulous Ridges

NCT04487379
View directory record Official record
Conditions
Ultrasonography
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 10, 2026, 1:18 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness in the Management of Irreversible Pulpitis

NCT04922229
View directory record Official record
Conditions
Irreversible Pulpitis
Interventions
RCT, Pulpotomy
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 99 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 10, 2026, 1:18 PM EDT
Withdrawn Not applicable Interventional

Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients

NCT04996641
View directory record Official record
Conditions
Pulpitis - Irreversible, Caries, Head and Neck Cancer
Interventions
Root canal treatment and crown
Procedure
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 10, 2026, 1:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Photobiomodulation and Tooth Analgesia

NCT06691269
View directory record Official record
Conditions
Dental Anaesthesia, Dental Pain, Dental Analgesia
Interventions
Photobiomodulation, Topical Benzocaine, Local Anesthesia
Device · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
6 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Phase 4 Interventional Results available

Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation

NCT02864862
View directory record Official record
Conditions
Dental Implant, Immediate Dental Implant, Soft Tissue Augmentation
Interventions
Immediate implant, SCTG, ADM
Device · Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation

NCT00980278
View directory record Official record
Conditions
Tooth Loss
Interventions
Sinus lift augmentation and dental implant, Aastrom BRCs
Procedure · Biological
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

CATER: Comprehensive Alveolar and Tooth Esthetic Replacement

NCT04082143
View directory record Official record
Conditions
Dental Implant Failure Nos
Interventions
Allograft mucosal enhancement with dental implant, No allograft mucosal enhancement at time of dental implant placement
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implant Placement With Simultaneous Gum Grafting

NCT01431144
View directory record Official record
Conditions
Edentulous
Interventions
connective tissue autograft, connective tissue allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation

NCT06296459
View directory record Official record
Conditions
Dental Implant
Interventions
3D R100 scanner, Conventional Radiograph
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 10, 2026, 1:18 PM EDT
Terminated Not applicable Interventional Results available

Lithium Disilicate (CAD/CAM) Fixed Partial Dentures (FPD) Clinical Study

NCT03036566
View directory record Official record
Conditions
Missing Tooth
Interventions
Lithium disilicate ceramic (Ivoclar)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Oct 10, 2026, 1:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Diabetes Effects on Long-Term Implant Survival and Success

NCT02282046
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
25 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 10, 2026, 1:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Initial Stability of Posterior Maxillary Implants With Bicortical Fixation

NCT01237184
View directory record Official record
Conditions
Tooth Loss
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 10, 2026, 1:18 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Internal Irrigation Surgery

NCT07715825
View directory record Official record
Conditions
Dental Implant Healing, Partial Edentulism Class 1, Partial Edentulism Class II, Partial Edentulism Class 3
Interventions
Irrigation-Integrated Surgical Guide, Conventional Surgical Guide
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
25 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Straumann Roxolid Multi-Center Study

NCT01842958
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Straumann Bone Level Implants, 4.1 mm implant diameter, Straumann Bone Level Implants, 3.3 mm implant diameter
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2018 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction

NCT02844569
View directory record Official record
Conditions
Tooth Extraction
Interventions
Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 10, 2026, 1:18 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis

NCT03553095
View directory record Official record
Conditions
Chronic Periodontitis, Depression
Interventions
Periodontal Surgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 10, 2026, 1:18 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Synthetic Bone Graft for Treatment of Peri-implantitis

NCT03213210
View directory record Official record
Conditions
Peri-Implantitis
Interventions
easy-graft CLASSIC (beta-Tricalcium Phosphate)
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 10, 2026, 1:18 PM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Dental Implant

NCT00991965
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
6
States / cities
Loma Linda, California • Los Angeles, California • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 10, 2026, 1:18 PM EDT
Completed Not applicable Interventional Results available

Study on OsseoSpeed™ Implants Replacing 2-5 Teeth in the Posterior Upper Jaw, Restored With Provisional Teeth Attached 6-7 Weeks Later

NCT00711113
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
2
States / cities
Iowa City, Iowa • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2014 · Synced Oct 10, 2026, 1:18 PM EDT