Independent directory Public ClinicalTrials.gov records United States
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Showing 1489–1512 of 3,591 matching trials from the live ClinicalTrials.gov search.
Conditions
Type1diabetes
Interventions
Artificial Pancreas Controller in Dual Hormone Mode, Artificial Pancreas Controller in Single Hormone Mode, Artificial Pancreas Controller in Predictive Low Glucose Suspend Mode, XeriSol glucagon
Device · Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Completed No phase listed Observational Accepts healthy volunteers

Macronutrient Distribution and Plasma Metabolites to Model Meals Composition

NCT04928872
Conditions
Glucose Metabolism
Interventions
Predefined meal
Combination Product
Lead sponsor
Texas A&M University
Other
Eligibility
60 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
College Station, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pilot Study: Snacking, Willpower and Glucose Availability

NCT02258477
Conditions
Willpower
Interventions
Sequence 1, Sequence 2, Sequence 3, Sequence 4
Dietary Supplement
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Not listed Not applicable Interventional

MANAGE Automated Glucose Monitoring

NCT02211300
Conditions
ICU/CCU Patients Requiring Blood Glucose Monitoring
Interventions
The OptiScanner, YSI 2300 STAT Plus™
Device
Lead sponsor
OptiScan Biomedical Corporation
Industry
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Boston, Massachusetts • St Louis, Missouri • Portland, Oregon + 1 more
Conditions
Obesity, Prediabetic State, Type 2 Diabetes
Interventions
Health Education and Coaching Strategy, Dietary consult
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 21 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prediabetes Stratification by Multi-omics Profile After Food Intake

NCT06005051
Conditions
Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Dietary intervention
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Conditions
Insulin Resistance
Interventions
one bout of 45 minutes exercise
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Type 2 Diabetes Mellitus
Interventions
Alogliptin, Alogliptin placebo, Pioglitazone, Pioglitazone placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
72
States / cities
Birmingham, Alabama • Columbiana, Alabama • Huntsville, Alabama + 69 more
Conditions
Gestational Diabetes Mellitus
Interventions
Low-Carbohydrate/Higher Fat Diet, High Carbohydrate/Low fat diet
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Bone Metastases, Cancer Survivor, Metastatic Malignant Neoplasm in the Bone
Interventions
Monitoring Device, Physical Activity Measurement, Quality-of-Life Assessment, Questionnaire Administration, Standard Follow-Up Care, Survey Administration
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans

NCT01762046
Conditions
Diabetes Mellitus, Type 2
Interventions
Glipizide, Metformin, Oral Glucose Tolerance Test
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
1,033 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

5HT2CR Balance in Brain Connectivity in Cocaine Dependence

NCT03921151
Conditions
Cocaine Dependence
Interventions
Mirtazapine 15 MG Oral Tablet
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Type 2 Diabetes
Interventions
Pharmacist Only, Continuous Glucose Monitor (CGM), Community Health Worker (CHW)
Behavioral · Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
25 Years to 75 Years
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Type 2 Diabetes Mellitus
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Huntington Park, California • Los Angeles, California • Montclair, California + 24 more
Completed Not applicable Interventional Accepts healthy volunteers

Data Acquisition to Model Glycemic Response

NCT03612999
Conditions
Healthy
Interventions
Dexcom continuous glucose monitor, Fitbit activity tracker, Subjects record daily activity, Subjects record psychological state
Device · Behavioral
Lead sponsor
Savvysherpa, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minnetonka, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of Coffee on Glucose Metabolism

NCT00950898
Conditions
Type 2 Diabetes
Interventions
decaff, caffcoff, caffeine, placebo
Other
Lead sponsor
Brooklyn College of the City University of New York
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Brooklyn, New York
Enrolling by invitation Phase 4 Interventional Accepts healthy volunteers

Imaging Biomarkers of Pancreatic Function and Disease

NCT05659147
Conditions
Pancreatitis, Diabetes Mellitus
Interventions
Research MRI without administration of intravenous secretin, Research MRI with administration of intravenous secretin, Genetic Sequencing, Blood Tests, Stool Tests, Survey Completion, Endoscopic pancreatic function tests (ePFTs), Secretin
Diagnostic Test · Genetic · Other + 1 more
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 21 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Active, not recruiting Phase 2Phase 3 Interventional Results available

SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes

NCT06149793
Conditions
Cystic Fibrosis-related Diabetes, Cystic Fibrosis
Interventions
Empagliflozin, Placebo Control
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Hysterectomy
Interventions
50% dextrose, Normal Saline
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Scottsdale, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Index of Table Grape Varietals

NCT03248609
Conditions
Healthy
Interventions
Milano grapes, Table grapes, Grape juice, Glucose beverage
Other
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Davis, California
Conditions
Type 1 Diabetes, Type 2 Diabetes
Interventions
Virtual Clinic
Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Completed Phase 2 Interventional Results available

Chemoradiation or Brachytherapy for Rectal Cancer

NCT02017704
Conditions
Rectal Cancer
Interventions
Endo-HDR (if randomized to this arm), capecitabine and IMRT (if randomized to this arm), IMRT (intensity modulated radiation therapy), FOLFOX6, Surgery
Radiation · Drug · Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 100 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
4
States / cities
Tampa, Florida • Atlanta, Georgia • Baltimore, Maryland + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Effects of Non-nutritive Sweeteners

NCT02413424
Conditions
Obesity
Interventions
Sucralose, Water, glucose load
Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 40 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Type 1 Diabetes
Interventions
C-Carbs Program
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California