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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: dry needling Clear all
Completed Not applicable Interventional

TDN, Manual Therapy and Exercise For the Management of Achilles Tendinopathy

NCT02532595
View directory record Official record
Conditions
Achilles Tendon Injury
Interventions
manual therapy and exercise, trigger point dry needling
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pathophysiology of Post Amputation Pain

NCT01632709
View directory record Official record
Conditions
Amputation Stumps, Neuroma
Interventions
Bupivacaine, Placebo
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2015 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Intramuscular Electrical Stimulation for the Treatment of Trigger Points in Patients With Migraine

NCT05893914
View directory record Official record
Conditions
Chronic Migraine
Interventions
Dry Needling and intramuscular electrical stimulation to trigger points
Procedure
Lead sponsor
Thomas W. Perreault, PT
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dover, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

VCOM Pain Free Research Collaborative

NCT06533345
View directory record Official record
Conditions
Chronic Pain
Interventions
Behavior Change Coaching, Nutrition, Autonomic Recalibration, Dry Needling, Osteopathic Manipulative Treatment, Counseling Psychology, Multiple Treatments
Behavioral · Other · Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
21 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dry Needling Multifidus on Thickness of Transversus Abdominis in Healthy Individuals

NCT01734577
View directory record Official record
Conditions
Back Pain
Interventions
Dry needling, Sham needling
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling to the Multifidus Muscle in Subjects With Low Back Pain

NCT02284724
View directory record Official record
Conditions
Low Back Pain, Mechanical
Interventions
Dry Needling, Sham Needling
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

NCT07112404
View directory record Official record
Conditions
Pain, Back Pain, Lower Back Pain, Quality of Life
Interventions
Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Decrease of Muscle Biomechanical Stiffness Following Dry Needling in Asymptomatic Participants

NCT04864704
View directory record Official record
Conditions
Healthy
Interventions
dry needling
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 2, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional

Dry Needling for Patients With Back Pain

NCT03586778
View directory record Official record
Conditions
Back Pain
Interventions
dry needling, manual therapy, therapeutic exercise
Other
Lead sponsor
Concord Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 2, 2026, 9:14 PM EDT
Terminated Not applicable Interventional

Comparison of Platelet Rich Plasma and Alternative Therapies for the Treatment of Tennis Elbow (Lateral Epicondylitis)

NCT01668953
View directory record Official record
Conditions
Lateral Epicondylitis (Tennis Elbow)
Interventions
Platelet Rich Plasma (PRP) Injection, Whole Blood Injection, Dry Needle Fenestration, Sham Injection
Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Sep 2, 2026, 9:14 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Dry Needling the Calf Muscles on Biomechanics and Muscle Function in Individuals With Restricted Dorsiflexion

NCT07474948
View directory record Official record
Conditions
Ankle Stiffness
Interventions
Dry needling
Procedure
Lead sponsor
University of Dayton
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II

NCT06502951
View directory record Official record
Conditions
Cervicogenic Headache, Whiplash Injuries
Interventions
Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Terminated Not applicable Interventional

Manual Therapy to Treat Gluteus Medius Trigger Points

NCT02333617
View directory record Official record
Conditions
Anterior Knee Pain Syndrome, Patellofemoral Pain Syndrome
Interventions
Dry Needling, Soft Tissue Mobilization, Placebo Control, Hip and core strengthening exercises
Other
Lead sponsor
Mitchell Selhorst
Other
Eligibility
13 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling Practice in Colorado: Practitioner and Patient

NCT04040218
View directory record Official record
Conditions
Dry Needling, Harm
Interventions
Dry Needling
Procedure
Lead sponsor
Regis University
Other
Eligibility
18 Years and older
Enrollment
2,607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 2, 2026, 9:14 PM EDT
Active, not recruiting Not applicable Interventional

Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance

NCT06275074
View directory record Official record
Conditions
Neck Pain, Sleep Disturbance
Interventions
Dry Needling, Therapeutic Exercise
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot

NCT04487327
View directory record Official record
Conditions
Ankle and or Hindfoot Injury
Interventions
Dry Needling
Other
Lead sponsor
Regis University
Other
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immediate Effect of Dry Needling of the Lumbar Multifidus on Pain Sensitivity In A Healthy Population

NCT05845697
View directory record Official record
Conditions
Low Back Pain
Interventions
Trigger point dry needling, Sham dry needling
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Dry Needling in Multiple Sclerosis

NCT06394310
View directory record Official record
Conditions
Multiple Sclerosis, Spasticity
Interventions
Dry needling, Sham dry needling
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only

NCT02646579
View directory record Official record
Conditions
Plantar Fasciitis, Achilles Tendinitis, Patellofemoral Pain Syndrome
Interventions
Spinal and Peripheral Dry Needling, Peripheral Dry Needling
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 2, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Dry Needling and STM on Pain Management for Anterior Cruciate Ligament Reconstruction (ACLR)

NCT03506685
View directory record Official record
Conditions
Pain and Anterior Cruciate Ligament Reconstruction
Interventions
Dry needling and STM
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Not yet recruiting Not applicable Interventional

Conservative Care for Pelvic Pain (C2P2) in Women Service Members

NCT06697548
View directory record Official record
Conditions
Chronic Pelvic Pain
Interventions
Pain Neuroscience Education, Lumbopelvic and Hip Therapeutic Exercise, Extrapelvic Manual Therapy, Extrapelvic Dry Needling, Deep Paced Diaphragmatic Breathing Training, Chronic Pelvic Pain Education, Intravaginal and intrarectal pelvic floor physical therapy
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Antonio, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Dry Needling Versus Conventional Physical Therapy in Patients With Plantar Fasciitis

NCT02373618
View directory record Official record
Conditions
Plantar Fasciitis
Interventions
DN and conventional PT, Conventional PT
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Sep 2, 2026, 9:14 PM EDT
Not listed Not applicable Interventional

Effectiveness of Dry Needling in Linear Scar Tissue

NCT06033430
View directory record Official record
Conditions
Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar, Dry Needling
Interventions
True dry needling, Sham dry needling
Other
Lead sponsor
Iran University of Medical Sciences
Other
Eligibility
20 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Dry Needling in Multiple Sclerosis

NCT07615725
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 2, 2026, 9:14 PM EDT