- Conditions
- E-cigarette Use, Cigarette Smoking, Harm Reduction, Tobacco Use
- Interventions
- E-cigarettes, Oral nicotine pouches
- Other
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 173
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Smoking, Tobacco Use
- Interventions
- Low Power, High Power, Low Concentration, High Concentration
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Nicotine Use Disorder
- Interventions
- E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Addiction Nicotine
- Interventions
- VapeAway filter system
- Device
- Lead sponsor
- VapeAway
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Smoking
- Interventions
- E-cigarette
- Other
- Lead sponsor
- Prisma Health-Upstate
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Greenville, South Carolina
- Conditions
- Smoking, Tobacco
- Interventions
- P2611222, P2615022, P2615122, P2613422
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 668 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 27
- States / cities
- Chandler, Arizona • Fort Smith, Arkansas • Altamonte Springs, Florida + 21 more
- Conditions
- Tobacco Dependence
- Interventions
- Nicotine-Containing Electronic Cigarette, Non-Nicotine Electronic Cigarette
- Other
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Cardiovascular Risk Factor, Nicotine Dependence
- Interventions
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Healthy Volunteers
- Interventions
- Combustible Cigarette, blu Disposable A, blu Disposable B, blu Disposable C, blu Disposable D, blu Disposable E
- Other
- Lead sponsor
- Fontem US LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Burbank, California
- Conditions
- Electronic Cigarette Use
- Interventions
- RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Subject Usual Brand ENDS
- Other
- Lead sponsor
- Cheerain HK Limited
- Industry
- Eligibility
- 22 Years to 59 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Cypress, California • Overland Park, Kansas
- Conditions
- Electronic Cigarette Use
- Interventions
- Tobacco product administration and assessment, own brand cigarettes, Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine
- Other
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Health Behavior
- Interventions
- Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor
- Drug
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Electronic Cigarette Use
- Interventions
- RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Usual Brand Cigarette, Nicorette White Ice Mint nicotine polacrilex gum
- Other
- Lead sponsor
- Cheerain HK Limited
- Industry
- Eligibility
- 22 Years to 59 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Tobacco Dependence
- Interventions
- Flavor
- Other
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
- Interventions
- E-cigarette Cessation Manual
- Behavioral
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Electronic Cigarettes
- Interventions
- E-cigarette Lab Session 15 watts, 10 mg nicotine, E-cigarette Lab Session 15 watts, 30 mg nicotine, E-cigarette Lab Session 30 watts, 10 mg nicotine, E-cigarette Lab Session 30 watts, 30 mg nicotine, Own Brand Session - E-cigarette, Own Brand Session - E-cigarette/Cigarette
- Other
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 21 Years to 55 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Nicotine Vaping, Nicotine, Vaping
- Interventions
- CA35, CM35, Cig
- Other
- Lead sponsor
- Philip Morris Products S.A.
- Industry
- Eligibility
- 24 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- High Point, North Carolina
- Conditions
- Nicotine Addiction
- Interventions
- Nicotine patch and gum, Minnesota Nicotine Withdrawal Scale (MNWS), ASSIST (the Alcohol, Smoking and Substance Involvement Screening), Counseling, NIDA Standardized Research E-cigarettes (SREC)
- Other · Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cardiovascular Risk Factor, Nicotine Dependence
- Interventions
- Electronic Cigarette
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Tobacco Dependence
- Interventions
- CEASE, CEASE + BIO
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 865 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
- Interventions
- Acute (24-hour) abstinence, Ad libitum smoking/vaping
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Nicotine Use Disorder, Substance Use Disorders
- Interventions
- TI-NDBS, Sham TI-NDBS
- Device
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Bloomington, Indiana • Indianapolis, Indiana
- Conditions
- Cigarette Smoking Toxicity, Nicotine, Acute Cardiovascular Disease
- Interventions
- Prazosin
- Drug
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years to 40 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
- Interventions
- E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 44 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut