Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 439 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: e-cigarettes Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Electronic Cigarettes vs Combustible Cigarettes and Nicotine Gum

NCT02269514
View directory record Official record
Conditions
Smoking
Interventions
Own Brand Cigarette, Electronic Cigarette #1, Electronic Cigarette #2, Electronic Cigarette #3, Leading U.S. Nicotine Gum
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 4, 2018 · Synced Oct 29, 2026, 4:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Electronic Cigarettes on Perinatal Immune Responsiveness and Birth Outcomes

NCT02553577
View directory record Official record
Conditions
Immune Response, Birth Weight, Gestational Age
Interventions
Not listed
Lead sponsor
Kristin Ashford
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Do Flavors Increase the Addiction Potential of Nicotine?

NCT04696380
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine, JUUL e-cigarette
Drug · Device
Lead sponsor
University of Vermont
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Responses to E-Cigarette Advertising

NCT04249219
View directory record Official record
Conditions
E-Cig Use
Interventions
Viewing e-cigarette ads
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 26 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2023 · Synced Oct 29, 2026, 4:06 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Understanding Oral Nicotine Pouch Use in Healthy Volunteers

NCT07829939
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
0 mg oral nicotine pouches, 3 mg oral nicotine pouches, 6 mg oral nicotine pouches, cigarette or e-cigarette
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adverse Airway Effects From Tobacco and E-Cigarettes

NCT03251053
View directory record Official record
Conditions
Airway Morbidity, Smoking Cessation, Nicotine Adverse Reaction, Smoking, Tobacco, Smoking, Cigarette
Interventions
Electronic cigarette use, Control regular cigarette smokers
Device · Other
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarettes as a Harm Reduction Strategy

NCT06277271
View directory record Official record
Conditions
Smoking
Interventions
E-cigarette
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

User Acceptability of a Nicotine Lactate Delivery System (P3L)

NCT02643693
View directory record Official record
Conditions
Smoking
Interventions
P3L, VUSE, CC
Other
Lead sponsor
Philip Morris Products S.A.
Industry
Eligibility
19 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 29, 2026, 4:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

NCT05896033
View directory record Official record
Conditions
Smoking Prevention and Control
Interventions
Non-Menthol Cigarettes, Tobacco Flavored E-cigarettes, Menthol Cigarettes, Menthol Flavored E-cigarettes
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Recruiting Phase 2 Interventional

The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction

NCT07322432
View directory record Official record
Conditions
Addiction Nicotine
Interventions
VapeAway filter system
Device
Lead sponsor
VapeAway
Industry
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Phase 4 Interventional Results available

The END Perioperative Smoking Pilot Study

NCT02482233
View directory record Official record
Conditions
Smoking, Nicotine Addiction, Surgery
Interventions
ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling, brief advice, brochure
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Results available

Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents

NCT03786042
View directory record Official record
Conditions
Attentional Bias, Smoking Cues, Positive Perceptions About Cigarette Smoking, Social Norms, Smoking Susceptibility
Interventions
E-cigarette ad exposure, non e-cigarette TV commercials
Behavioral · Other
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
14 Years to 17 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 29, 2026, 4:06 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status

NCT07038317
View directory record Official record
Conditions
Vaping Behaviors, Message Exposure, Young Adults
Interventions
Intervention, Control
Other
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years to 24 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional

Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization

NCT02099097
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
web-based video game (Quit IT), Questionnaires, Salvia sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Oct 29, 2026, 4:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vape-Free Text-Messaging: Pilot Study

NCT05906082
View directory record Official record
Conditions
E-cigarette Use
Interventions
E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
Behavioral
Lead sponsor
Jovan Gwon, PhD, RN, FIAAN
Other
Eligibility
18 Years to 24 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 29, 2026, 4:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Young Adult EC Use and Respiratory Outcomes

NCT04395274
View directory record Official record
Conditions
E Cig Use
Interventions
Not listed
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 25 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults

NCT07702435
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Behavioral Intervention, Survey Administration
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Vaping Nicotine on Cognition in Young Adults

NCT04901208
View directory record Official record
Conditions
Nicotine Addiction, Vaping
Interventions
Nicotine pod, Placebo pod
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 29, 2026, 4:06 AM EDT
Not yet recruiting Not applicable Interventional

Impact of Electronic Cigarette Temperature and Solvent on Biomarkers

NCT07612696
View directory record Official record
Conditions
Oxidative Stress, Tobacco Use, Electronic Cigarettes
Interventions
High temperature wattage setting on electronic cigarette, Low temperature wattage setting on electronic cigarette, High concentration of Propylene Glycol, Low concentration of Propylene Glycol
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

NCT02498145
View directory record Official record
Conditions
Smoking, Nicotine Dependence
Interventions
Nicotine e-cigarette, Non-nicotine e-cigarette
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 29, 2026, 4:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-Cigarettes and SNA

NCT02724241
View directory record Official record
Conditions
Nicotine Dependence
Interventions
one time exposure to e-cig with nicotine, One time exposure to e-cigarette without nicotine, one time exposure to empty e-cigarette
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Oct 29, 2026, 4:06 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Identifying Student Opinion Leaders to Lead E-cigarette Interventions

NCT04083469
View directory record Official record
Conditions
E-Cig Use, Adolescent Behavior
Interventions
Peer-Led Peer-Elected Intervention, Adult-Led Intervention, Peer-Led Non-Elected Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
686 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 29, 2026, 4:06 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model

NCT03031145
View directory record Official record
Conditions
Tobacco Smoking, Healthy Participants, E-cigarette Smokers
Interventions
Felis Domesticus
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 29, 2026, 4:06 AM EDT
Not listed Not applicable Interventional

The Effect of Electronic Cigarette Use on Smoking Behaviors Among Smokers Receiving Outpatient Psychiatric Treatment

NCT04014322
View directory record Official record
Conditions
Tobacco Smoking, Psychiatric Disorders
Interventions
E-cigarette
Other
Lead sponsor
Fordham University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 29, 2026, 4:06 AM EDT