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ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:05 AM EST

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Showing 49–72 of 426 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: electronic cigarette Clear all

Conditions: Electronic Cigarette Use
Interventions: Electronic Cigarette containing nicotine, Electronic Cigarette without nicotine; Device
Lead sponsor: Michigan Technological University; Other
Eligibility: 21 Years to 40 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Houghton, Michigan

Conditions: Tobacco Use Disorder
Interventions: electronic cigarette, nicotine inhaler; Other · Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Nicotine Use Disorder
Interventions: E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6); Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cardiovascular Risk Factor, Nicotine Dependence
Interventions: Electronic Cigarette; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: San Francisco, California

Conditions: E-cigarette Use
Interventions: CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 10 Years to 15 Years
Enrollment: 2,059 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Nicotine Dependence
Interventions: e-cig with nicotine, e-cig without nicotine, nicotine inhaler, sham control; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Marijuana Dependence
Interventions: Nicotine, Cannabis, PAX Loose Leaf Vaporizer; Drug · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Adult Participants
Interventions: 0 mg oral nicotine pouches, 3 mg oral nicotine pouches, 6 mg oral nicotine pouches, cigarette or e-cigarette; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Nicotine Dependence
Interventions: Nicotine, Vaporizer Device, Salt-HIgh Nicotine Unflavored (Product B), Free-Low Nicotine Tobacco Flavored (Product C), Salt-High Nicotine Tobacco Flavored (Product D); Drug · Device
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years to 55 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Nicotine Vaping
Interventions: Kick-Nic! mobile phone application, NCI Quit Vaping website; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 12 Years to 19 Years
Enrollment: 306 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
Interventions: E-cigarette Cessation Manual; Behavioral
Lead sponsor: Florida International University; Other
Eligibility: 14 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Health Behavior, Risk Reduction Behavior
Interventions: HD2+; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 2,440 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Vaping
Interventions: Social Media Intervention; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 13 Years to 21 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cigarette Smoking, E-cigarette Use
Interventions: Nicotine Content, Illegal cigarette price, E-cigarette price; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Vaping Behaviors
Interventions: Label with text health warning, Label with pictorial health warning, Label with neutral statements about vaping; Other
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 1,369 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Substance Withdrawal Syndrome
Interventions: Abstinence from e-cigarettes; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Electronic Cigarette Use, Tobacco Smoking
Interventions: JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum; Other
Lead sponsor: Juul Labs, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 137 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 2
States / cities: Kansas City, Kansas • Lexington, Kentucky

Conditions: E-cigarette Use, Vaping
Interventions: Peer Messaging, Peer Coaching via Text, Gamification, E-Cigarette Cessation Materials; Behavioral · Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 13 Years to 19 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Electronic Cigarette Use
Interventions: RELX ENDS Tobacco Flavor 1, RELX ENDS Tobacco Flavor 2, RELX ENDS Menthol Flavor 1, RELX ENDS Menthol Flavor 2; Other
Lead sponsor: Cheerain HK Limited; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Burbank, California

Conditions: Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking, Incentives, Engagement, Patient, Peer Support, Media Literacy
Interventions: Text-massaging suport, Financial incentive, Media literacy; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years to 29 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Smoking, Endothelial Dysfunction
Interventions: Electronic hookah vaping with nicotine, Electronic hookah vaping without nicotine; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 39 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Healthy
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 21 Years to 35 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking Cessation
Interventions: BIDI Stick e-cigarette; Other
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Electronic Cigarettes
Interventions: e-Cigarette; Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Vaporized Nicotine and Autonomic Control

Electronic Cigarettes or Nicotine Inhaler for Smoking Cessation

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power

Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath

E-cigarettes, Nicotine Inhaler, and Blood Vessel Function

Vaping THC From Electronic Cigarettes

Understanding Oral Nicotine Pouch Use in Healthy Volunteers

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study

Kick-Nic! Youth Quit Vaping App

Developing an E-Cigarette Cessation Intervention for Hispanic/Latina(o) Youth in Florida: The BReATHE Study

Multiple Risk Behavior Intervention in Health Care Settings

Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents

Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing

Impact of E-cigarette Device Warnings

Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?

Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems

Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping

Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers

Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation

Electronic Hookah and Endothelial Cell Function

Biology of the Oral Epithelium of E-Cigarette Smokers

Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette

Effects of e-Cigarettes on Perceptions and Behavior