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ClinicalTrials.gov public records Last synced Oct 10, 2026, 5:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 130 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: enhanced comprehensive care Clear all
Completed Not applicable Interventional

Enhanced Collaborative Depression Treatment in Primary Care: The RESPECT-D-E Trial

NCT01583400
View directory record Official record
Conditions
Depressive Disorder, Major, Depressive Disorder, Minor, Dysthymic Disorder
Interventions
RESPECT-D, RESPECT-D-E (Enhanced)
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Keene, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 10, 2026, 5:51 PM EDT
Active, not recruiting Not applicable Interventional

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

NCT04660526
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use., Optimized first responder performance including earlier use of AEDs.
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

Investigation of Two Swallowing Therapy Models During Radiation Therapy for Head and Neck Cancer

NCT03832686
View directory record Official record
Conditions
Head Neck Cancer
Interventions
Virtual Coach
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Palo Alto, California • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity

NCT06245057
View directory record Official record
Conditions
Morbidity;Perinatal
Interventions
Maternity care home model (MCHM)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Not yet recruiting Not applicable Interventional

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

NCT06915428
View directory record Official record
Conditions
Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia, Preeclampsia (PE), Hypertensive Disorders of Pregnancy, Support Program, Stress, Resilience, Psychological, Empowerment, Patient, Emotional Stress, Pregnancy, Pregnancy Complications, Pregnancy Induced Hypertension, Neonates and Preterm Infants, Cervical Insufficiency, Social Determinants of Health (SDOH), Cervical Shortening, Disparities in Pregnancy Complications, Disparities, Prenatal Care, Care Coordination
Interventions
Care coordination, Electronic massage, support gift #1, Support gift #2, Support gift #3, Support gift #4, Additional PTBCARE+ support, Stress reduction toolkit - Visit 1 (V1), PTBCARE+ mobile application (app) and website, Sleep, meditation, and Wellness app, Emergency low blood sugar kit, Low dose aspirin (LDA), Visit #2 Stress Reduction Toolkit
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
1,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

An Integrated Telemedicine-Home Visitation Program to Increase Outcomes for Children With Medical Complexity

NCT03590509
View directory record Official record
Conditions
Chronic Disease
Interventions
Telemedicine Program, Usual Comprehensive Care
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Phase 3 Interventional

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

NCT06027099
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
Interventions
Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care
Drug · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Stanford, California • Kansas City, Kansas • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Brief New Treatment for Suicide Attempts

NCT03300596
View directory record Official record
Conditions
Suicide, Attempted, Drug Use, Alcohol; Use, Problem
Interventions
Brief intervention to prevent suicide attempt, Enhanced treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Oct 10, 2026, 5:51 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding

NCT05254015
View directory record Official record
Conditions
Hoarding Disorder, Obsessive-Compulsive Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Early Intervention for Youth at Risk for Bipolar Disorder

NCT01483391
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Disorder
Interventions
Enhanced Care, Family-Focused Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 17 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
3
States / cities
Los Angeles, California • Stanford, California • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Implementation of Electronic Shared Decision-Making Support for Early Intervention

NCT04562038
View directory record Official record
Conditions
Child Development Disorder, Development Delay
Interventions
Young Children's Participation and Environment Measure (YC-PEM) electronic patient-reported outcome (e-PRO)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
3 Months to 36 Months
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

Primary Care Evidence-based Approach for Improving Lifelong Health

NCT06526312
View directory record Official record
Conditions
Clinical Trial
Interventions
SMS/Text (CAMPI), Fidelity Monitoring (Lyssn and COACH), Family Check-Up 4 Health (FCU4Health)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
2 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

The Navigator Project

NCT02106702
View directory record Official record
Conditions
HIV
Interventions
Navigator enhanced case-management, Forensic AIDS Project
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 10, 2026, 5:51 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor

NCT07660666
View directory record Official record
Conditions
Melanoma
Interventions
Electronic Health Record Review, Internet-Based Intervention, Patient Navigation, Survey Administration
Other · Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Telehealth Multi-Component Optional Model (MOM) Study

NCT06095960
View directory record Official record
Conditions
Maternal Health
Interventions
Telehealth MOM, Enhanced Standard of Care
Behavioral · Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
6
States / cities
El Dorado, Arkansas • Fayetteville, Arkansas • Fort Smith, Arkansas + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Elders Preserving Independence in the Community

NCT05381480
View directory record Official record
Conditions
Healthy Aging
Interventions
In-home Preventive Health Visits by Advanced Practice Nurse, On-site Evidence-based Physical Activity, Health and Wellness Classes
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
55 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320
View directory record Official record
Conditions
Unhealthy Alcohol Use
Interventions
Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Interventions to Increase Colorectal Cancer Screening

NCT03200366
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Tailored DVD, Patient Navigation
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
45 Years to 75 Years
Enrollment
371 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 10, 2026, 5:51 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Social, Emotional, Behavioral, and Academic Functioning

NCT05425381
View directory record Official record
Conditions
Depression, Anxiety, Disruptive Behavior Disorder, Trauma, Psychological
Interventions
Enhanced version of Interconnected Systems Framework, Positive Behavioral Interventions and Supports with Co-located School Mental Health
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
Not listed
Enrollment
1,208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Greenville, North Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Medication Maintenance Therapy in Community Pharmacy Settings

NCT03766893
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Buprenorphine / Naloxone Oral Product, injectable naltrexone, Pharmacy maintenance addiction care
Drug · Other
Lead sponsor
Lifespan
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 10, 2026, 5:51 PM EDT
Active, not recruiting Not applicable Interventional

Mobile Health for Adherence in Breast Cancer Patients

NCT06112613
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention
Other · Procedure · Behavioral
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
499
States / cities
Fairbanks, Alaska • Kingman, Arizona • Phoenix, Arizona + 338 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

E-PRIME For Children With Medical Complexity

NCT06216548
View directory record Official record
Conditions
Children With Medical Complexity
Interventions
Usual Care and Enhanced Primary Care, Enhanced Primary Care
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 17 Years
Enrollment
909 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Not yet recruiting Not applicable Interventional

Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis

NCT07492602
View directory record Official record
Conditions
Stroke, Traumatic Brain Injury, Multiple Sclerosis
Interventions
Functional Electrical Stimulation, Normal care
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry

NCT07088770
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
Interventions
Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion, Tech-mediated Peer Navigation Enhanced Case management (NCM)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kingston, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 10, 2026, 5:51 PM EDT