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Showing 1–24 of 179 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: extubation Clear all
Withdrawn Not applicable Interventional

Electrical Impedence Tomography With ENLIGHT2100

NCT05098834
View directory record Official record
Conditions
Extubation
Interventions
ENLIGHT 2100 ventilatory electrical impedance tomograph
Device
Lead sponsor
Duke University
Other
Eligibility
Up to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT05975385
View directory record Official record
Conditions
Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative, Pain, Postoperative
Interventions
Acupuncture
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Establishing Optimal PEEP Setting for Obese Patients in the Steep Trendelenburg Position

NCT06518239
View directory record Official record
Conditions
Obesity
Interventions
Peep Belt
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
19 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Not listed No phase listed Observational

Predictors of Respiratory Failure Following Extubation in the SICU

NCT01967056
View directory record Official record
Conditions
Muscle Weakness, Renal Failure, Respiratory Comorbidities
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE)

NCT06029244
View directory record Official record
Conditions
Delirium, Delirium in Old Age, Critical Illness, Intensive Care Unit Delirium
Interventions
EyeControl-Pro, Control
Device · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
50 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 10, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery

NCT07706504
View directory record Official record
Conditions
Neuromuscular Blockade
Interventions
TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand), TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand)
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Enrolling by invitation Not applicable Interventional

Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study

NCT07277244
View directory record Official record
Conditions
Robotic Surgery, Post Operative Pulmonary Complications
Interventions
Low Intensity Mechanical Ventilation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Recruiting No phase listed Observational

Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children

NCT07613918
View directory record Official record
Conditions
Critical Illness, Pediatric Critical Illness, Respiratory Failure, Traumatic Brain Injury, Cardiac Arrest
Interventions
Transcranial Doppler
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Day to 17 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 2 Interventional Results available

Lidocaine as an Endotracheal Tube (ETT) Cuff Media

NCT03343080
View directory record Official record
Conditions
Cardiac Disease
Interventions
1.8% lidocaine plus 0.76% sodium bicarbonate, Air
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 10, 2026, 2:04 AM EDT
Not listed Phase 2Phase 3 Interventional

Opioid Free Anesthesia vs. Opioid Anesthesia Techniques.

NCT03367988
View directory record Official record
Conditions
Analgesic Drug Dependence, Colectomy
Interventions
Opioid Anesthesia, Opioid-free Anesthesia
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 10, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
26
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing (RESCUE1)

NCT03107949
View directory record Official record
Conditions
Ventilator Induced Diaphragm Dysfunction
Interventions
Lungpacer DPTS (Diaphragm Pacing Therapy System)
Device
Lead sponsor
Lungpacer Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Gainesville, Florida • New York, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Study of High Blood Sugars and Insulin in Hospitalized, Critically Ill Children

NCT00487006
View directory record Official record
Conditions
Critical Illness, Hyperglycemia
Interventions
Serum Lab testing
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
2 Years to 12 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2015 · Synced Sep 10, 2026, 2:04 AM EDT
Not yet recruiting Not applicable Interventional

Perioperative High-flow Nasal Oxygen in Patients Undergoing Robotic Surgery

NCT07591610
View directory record Official record
Conditions
Robotic Surgery
Interventions
High flow nasal oxygen
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Not listed No phase listed Observational

Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill

NCT02112604
View directory record Official record
Conditions
Critically Ill, Obstructive Sleep Apnea
Interventions
Ventilator, Alice PDx, Pulmonary function test, Muscle strength tests, Grip strength measurement, Sedatives and muscle relaxants given in the ICU
Device · Other · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

High Flow Nasal Cannula With Noninvasive Ventilation

NCT04507425
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Standard of Care - Nasal Cannula, High-flow nasal cannula, HFNC plus non-invasive ventilation
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 4 Interventional Results available

Intubation Conditions Achieved With Rapid Co-administration of Rocuronium and Propofol Versus Classical Induction

NCT05509192
View directory record Official record
Conditions
Anesthesia
Interventions
MTPI, Classic Induction
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

METEOR Think NIV Pilot

NCT04052542
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Traditional online continuing education, Interprofessional education, Just-in-time education
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,328 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Sep 10, 2026, 2:04 AM EDT
Terminated Phase 2 Interventional Results available

Thiamine as a Metabolic Resuscitator After Cardiac Arrest

NCT03450707
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Thiamine 500 mg IV, Placebo
Drug · Other
Lead sponsor
Michael Donnino
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study

NCT03611374
View directory record Official record
Conditions
Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
Interventions
Bilateral Erector Spinae Plane Block (ESPB)
Procedure
Lead sponsor
Stanford University
Other
Eligibility
0 Years to 99 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Withdrawn Not applicable Interventional

Effects of Different PEEP Levels on Work of Breathing in Morbidly Obese Patients Prior to and After Extubation

NCT02492113
View directory record Official record
Conditions
Obesity
Interventions
Positive end-expiratory pressure (PEEP), ZEEP
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Extubation Criteria in Children With Upper Respiratory Infection (URI)

NCT04155892
View directory record Official record
Conditions
Upper Respiratory Tract Infections
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 7 Years
Enrollment
760 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 4 Interventional Results available

Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery

NCT03643796
View directory record Official record
Conditions
Anterior Cervical Discectomy and Fusion (ACDF)
Interventions
Remifentanil, Ketamine, Dexmedetomidine
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Comparison of Propofol to Precedex With Propofol for Emergence and Recovery in Patients Having Craniotomy Surgery

NCT00848991
View directory record Official record
Conditions
Cranitomy Surgery
Interventions
Precedex, Propofol
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 9, 2012 · Synced Sep 10, 2026, 2:04 AM EDT