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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: femtosecond laser Clear all
Recruiting Phase 4 Interventional

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

NCT07140653
View directory record Official record
Conditions
Astigmatism
Interventions
Femto arcs, Light Adjustable Lens (LAL)
Other · Device
Lead sponsor
Center For Sight
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Venice, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional

Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery

NCT02561104
View directory record Official record
Conditions
Incipient Cataract, Senile Nuclear Sclerosis
Interventions
Laser-assisted cataract surgery., Traditional manual phacoemulsification
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 99 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser

NCT02315456
View directory record Official record
Conditions
Capsulorhexis
Interventions
capsulorhexis
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
45 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2020 · Synced Sep 16, 2026, 8:17 AM EDT
Completed No phase listed Observational

Long-term LASIK Follow up Study

NCT01695642
View directory record Official record
Conditions
Lasik Eye Surgery
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Phase 4 Interventional

Clear Corneal Incisions and Arcuate Incisions Utilizing FemtoSecond Laser Technology for Cataract Surgery

NCT01383057
View directory record Official record
Conditions
Cataracts
Interventions
Femtosecond Laser
Procedure
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Goodlettsville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 16, 2026, 8:17 AM EDT
Terminated Not applicable Interventional Results available

OCT-guided LALAK for KCN

NCT01901614
View directory record Official record
Conditions
Corneal Opacity, Keratoconus
Interventions
LALAK, IEK, Retrobulbar Block or General Anesthesia, optical coherence tomography (OCT), Topical Anesthesia, femtosecond laser
Procedure · Drug · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Results available

Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism

NCT04676451
View directory record Official record
Conditions
Astigmatism, Cataract
Interventions
Femto-AK
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Phase 4 Interventional

Laser Cataract Surgery With the Femtosecond Laser Technology

NCT01382823
View directory record Official record
Conditions
Cataracts
Interventions
Femtosecond Laser
Procedure
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Goodlettsville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Results available

LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser

NCT02060461
View directory record Official record
Conditions
Myopia
Interventions
FS200 femtosecond laser LASIK, IntraLase femtosecond laser LASIK
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Sep 16, 2026, 8:17 AM EDT
Completed No phase listed Observational Results available

The Accuracy of Flap Thickness Versus the Pre-determined Surgical Planning Using WaveLight® FS200

NCT05501795
View directory record Official record
Conditions
Myopia
Interventions
WaveLight® FS200 femtosecond laser
Device
Lead sponsor
Stephen Wexler
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 16, 2026, 8:17 AM EDT
Not listed Not applicable Interventional

Astigmatism Management With Iris-registration Guided Corneal Relaxing Incisions or Toric IOLs During Cataract Surgery

NCT05561296
View directory record Official record
Conditions
Astigmatism, Cataract
Interventions
Femtosecond laser assisted cataract surgery with astigmatism management
Procedure
Lead sponsor
Kenneth J Rosenthal
Other
Eligibility
18 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced Sep 16, 2026, 8:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

NCT04072289
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Visumax spherocylindrical treatment
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Sep 16, 2026, 8:17 AM EDT
Terminated Not applicable Interventional

OCT-guided LALAK in Children

NCT01579643
View directory record Official record
Conditions
Corneal Opacity
Interventions
OCT guided laser-assisted lamellar anterior keratoplasty (LALAK), Penetrating Keratoplasty (KP)
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Month to 18 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 16, 2026, 8:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness

NCT01365728
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
LASIK with the iFS femtosecond laser
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison of LASIK Outcomes Using Two Femtosecond Lasers

NCT03063164
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Intralase IFS150, Visumax
Device
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Visual Outcomes and Contrast Sensitivity After Myopic LASIK

NCT01746589
View directory record Official record
Conditions
Myopia
Interventions
bilateral myopic LASIK
Device
Lead sponsor
Daniel S. Durrie, MD
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2013 · Synced Sep 16, 2026, 8:17 AM EDT
Not listed Phase 4 Interventional

Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL

NCT04863742
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Drug
Lead sponsor
Sight Medical Doctors PLLC
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Brentwood, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 16, 2026, 8:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Venturi and Peristaltic Based Phacoemulsification in Femtosecond Laser Cataract Surgery

NCT03970525
View directory record Official record
Conditions
Cataract Senile
Interventions
Venturi pump, Peristaltic vacuum pump
Device
Lead sponsor
Wendell Scott
Other
Eligibility
22 Years to 90 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 2, 2023 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser

NCT02430428
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Carl Zeiss Meditec VisuMax Femtosecond Laser
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Greenwood Village, Colorado • Leawood, Kansas • Sioux Falls, South Dakota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes

NCT04126174
View directory record Official record
Conditions
Cataract
Interventions
femtosecond laser system arcuate corneal incision, Manual LRI
Device · Other
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
40 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 16, 2026, 8:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction

NCT05611294
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Sep 16, 2026, 8:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Retrospective Analysis of the Time Elements for Different Workflow Scenarios During Femtosecond Laser-assisted Cataract Surgery (FLACS) From the Surgeon, Staff, and Patient Perspectives.

NCT07038395
View directory record Official record
Conditions
Cataract
Interventions
workflow
Device
Lead sponsor
LensAR Incorporated
Industry
Eligibility
21 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 16, 2026, 8:17 AM EDT
Not listed Not applicable Interventional

Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)

NCT06500416
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
Device
Lead sponsor
Coastal Eye Surgeons PLLC
Other
Eligibility
50 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Greenwich, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 16, 2026, 8:17 AM EDT
Completed Not applicable Interventional

Femtosecond Laser Assisted Keratoplasty

NCT00802776
View directory record Official record
Conditions
Keratoconus
Interventions
Femtosecond laser assisted keratoplasty, PKP
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Sep 16, 2026, 8:17 AM EDT