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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:09 AM EDT

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Showing 1–24 of 475 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: fentanyl citrate Clear all
Terminated Not applicable Interventional Results available

Does Optimized General Anesthesia Care Reduce Postoperative Delirium?

NCT02604459
View directory record Official record
Conditions
Hip Fractures, Anesthesia, Delirium
Interventions
cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management, General anesthesia, propofol, fentanyl, sevoflurane
Device · Procedure · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
65 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Oct 23, 2026, 2:09 AM EDT
Recruiting Phase 3 Interventional

Ropivacaine and Fentanyl for Labor Epidural Initiation

NCT07076368
View directory record Official record
Conditions
Pregnancy, Labor and Delivery, Labor Analgesia
Interventions
Ropivacaine + Fentanyl
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help With Placement of Labor Analgesia in Pregnant Patients?

NCT02207972
View directory record Official record
Conditions
Pregnancy
Interventions
Use of Ultrasound, No ultrasound used
Device · Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploratory Bioavailability of Fentanyl Sublingual Spray Under Fasting Conditions

NCT02138396
View directory record Official record
Conditions
Bioavailability
Interventions
Fentanyl Sublingual Spray (FSS), Fentanyl Citrate Injection (FCI), Naltrexone
Drug
Lead sponsor
INSYS Therapeutics Inc
Industry
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional Results available

Compare Propofol to Fentanyl and Midazolam for Colonoscopy

NCT01488045
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer, Colonic Diverticulosis
Interventions
Fentanyl, Propofol, Midazolam
Drug
Lead sponsor
Trinity Health Michigan
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 23, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Combined Ketamine/Propofol for Emergency Department Procedural Sedation

NCT01126957
View directory record Official record
Conditions
Procedural Sedation and Analgesia
Interventions
Ketamine, Placebo, Fentanyl, Propofol
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
1 Year and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Phase 2 Interventional Results available

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

NCT03084536
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Female, Cancer of Breast
Interventions
Bupivacaine, Gabapentin, Celecoxib, Acetaminophen, Midazolam, Fentanyl
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional Results available

Nasopharyngeal Versus Nasal Cannula Oxygen Supplementation in Surgery Patients

NCT02219464
View directory record Official record
Conditions
Oxygen Administration During Deep Sedation
Interventions
Nasopharyngeal catheter, Nasal Cannula, Oxygen Supplementation, Sedation
Device · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
16 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Phase 4 Interventional Results available

Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring

NCT01327677
View directory record Official record
Conditions
Pain
Interventions
Fentanyl
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 23, 2026, 2:09 AM EDT
Enrolling by invitation Early Phase 1 Interventional

Assessment of Drug Liking In Peri-procedural Clinical Settings

NCT07015528
View directory record Official record
Conditions
Drug Liking
Interventions
Droperidol, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 2:09 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Intrapartum Epidural Fentanyl and Breastfeeding in the Immediate Postpartum Period: a Randomized, Controlled, Double-blinded Study

NCT01497509
View directory record Official record
Conditions
Neonatal Neurobehavior, Breastfeeding Outcomes
Interventions
Bolus 10mL 0.25% bupivacaine/ep 1:600,000; infusion 10mL/hour 0.25% bupivacaine and epi 1:800,000, Bolus 10mL 0.25% bupivacaine/ epinephrine 1:600,000;infusion 10mL/hour 0.25% bupivacaine, 2 mcg/mL fentanyl, and epinephrine 1:800,000, Bolus 10mL 0.25% bupivacaine, 10mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 2.5 mcg/mL fentanyl, and epi 1:800,000, Bolus 10mL 0.25% bupivacaine, 5 mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 3.5 mcg/mL fentanyl, and epi 1:800,000
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Phase 1Phase 2 Interventional

The Use of Methadone in Newborn Infants

NCT01327079
View directory record Official record
Conditions
Premature Birth of Newborn, Critically Ill
Interventions
Methadone
Drug
Lead sponsor
John van den Anker
Other
Eligibility
22 Weeks to 43 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Propofol Versus Propofol-Fentanyl as Sedation For Lumbar Puncture in Children With Acute Leukemia/Lymphoma

NCT00214370
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
Propofol-Fentanyl, Propofol alone
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy

NCT00587665
View directory record Official record
Conditions
Pain
Interventions
ketamine, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 12 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 14, 2017 · Synced Oct 23, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Results available

Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery

NCT01890707
View directory record Official record
Conditions
Surgery, Anesthesia, Pain
Interventions
General Anesthesia, Deep Sedation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 23, 2026, 2:09 AM EDT
Active, not recruiting Phase 3 Interventional

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

NCT06089707
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Naloxone Nasal Spray
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 23, 2026, 2:09 AM EDT
Not listed Phase 4 Interventional

Intranasal Fentanyl for Pain Management

NCT00882960
View directory record Official record
Conditions
Trauma, Pain
Interventions
intravenous fentanyl, intra-nasal fentanyl
Drug
Lead sponsor
Genesys
Other
Eligibility
14 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated May 4, 2011 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Dexmedetomidine to Treat Bariatric Surgery-associated Pain

NCT02880540
View directory record Official record
Conditions
Obesity
Interventions
Fentanyl, Morphine, Dexmedetomidine
Drug
Lead sponsor
Janelle Vaughns
Other
Eligibility
12 Years to 20 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 23, 2026, 2:09 AM EDT
Not listed Phase 4 Interventional

US-guided SAPB for Rib Fractures in the ED

NCT03619785
View directory record Official record
Conditions
Rib Fractures, Rib Fracture Multiple
Interventions
Bupivacaine, Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
Drug
Lead sponsor
Andrew A Herring
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 23, 2026, 2:09 AM EDT
Terminated Phase 4 Interventional Results available

Pediatric Ketamine Study for Pain Management

NCT02388321
View directory record Official record
Conditions
Pain
Interventions
Ketamine, Fentanyl
Drug
Lead sponsor
Antonios Likourezos
Other
Eligibility
3 Years to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2018 · Synced Oct 23, 2026, 2:09 AM EDT
Enrolling by invitation No phase listed Observational

Characterizing the EEG Signature of Fentanyl and Its Association With Drug Liking

NCT06699953
View directory record Official record
Conditions
Brain Activity Related to Opioid Administration, Brain Activity Related to Drug Liking
Interventions
Observational study in patients receiving fentanyl for surgery
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 23, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Results available

Infrared Pupillometry During General Anesthesia to Predict Pain

NCT02058511
View directory record Official record
Conditions
Postoperative Pain, Objective Assessment of Sedation
Interventions
Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs
Drug · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Phase 2 Interventional

Acute Neurological ICU Sedation Trial (ANIST)

NCT00390871
View directory record Official record
Conditions
Sedation
Interventions
Fentanyl/Dexmedetomidine, Fentanyl/Propofol, Fentanyl
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Oct 23, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Neuraxial Analgesia on Maternal Breastfeeding

NCT01074190
View directory record Official record
Conditions
Pain, Breastfeeding
Interventions
Group 1, Group 2, Group 3
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 23, 2026, 2:09 AM EDT