- Conditions
- Down Syndrome, Autonomic Dysfunction
- Interventions
- Fear Response, Cold Stress, Pain Response, Caffeine, 12-Hour Fast, Maximal Dynamic Exercise
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
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- Conditions
- Middle-ear Barotrauma
- Interventions
- flight/diving simulation, ET function testing at ambient pressure, nasal video-endoscopy
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 10 Years to 50 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania