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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: focal cryotherapy Clear all
Completed Not applicable Interventional

Focal Ablation of Cervical Precancer

NCT01709773
View directory record Official record
Conditions
High-grade Cervical Intraepithelial Neoplasia
Interventions
Focal treatment
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Sep 10, 2026, 9:45 AM EDT
Active, not recruiting Not applicable Interventional

Multi-center Clinical Study to Evaluate the C2 CryoBalloon Focal Ablation System

NCT02514525
View directory record Official record
Conditions
Barrett Esophagus
Interventions
CryoBalloon Ablation System
Device
Lead sponsor
Pentax Medical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
11
States / cities
Orange, California • Sarasota, Florida • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Phase 3 Interventional Results available

Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

NCT00186888
View directory record Official record
Conditions
Retinoblastoma, Retinal Neoplasm
Interventions
Enucleation, Vincristine, Carboplatin, Focal Therapies, External Beam Radiation, Vincristine and Topotecan, Vincristine + Carboplatin + Etoposide, vincristine, cyclophosphamide, and doxorubicin, Vincristine, Carboplatin and Etoposide, Periocular carboplatin, G-CSF
Procedure · Drug · Radiation + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 10, 2026, 9:45 AM EDT
Completed No phase listed Observational Results available

Prostate Cancer - Comparative Outcomes of New Conceptual Paradigms for Treatment

NCT04890314
View directory record Official record
Conditions
Prostate Cancer
Interventions
Patient-reported questionnaire
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
1,953 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Kansas City, Kansas • Albany, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 10, 2026, 9:45 AM EDT
Recruiting Phase 2 Interventional

An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer

NCT05454488
View directory record Official record
Conditions
Prostate Cancer
Interventions
Focal Cryoablation, Standard of Care, Quality-of-life Questionnaires
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Phase 1 Interventional

Intravitreal Carboplatin for the Treatment of Participants With Recurrent or Refractory Intraocular Retinoblastoma

NCT02792036
View directory record Official record
Conditions
Retinoblastoma
Interventions
Carboplatin, Maxitrol®, Focal Therapy, Plaque Radiotherapy
Drug · Procedure
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 17 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 10, 2026, 9:45 AM EDT
Recruiting No phase listed Observational

Ablative Therapy in the Management of Prostate Cancer

NCT03492424
View directory record Official record
Conditions
Prostate Cancer
Interventions
cryotherapy
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2039
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Not applicable Interventional

Investigating and Characterizing the Immune Response to Prostate Cancer

NCT03331367
View directory record Official record
Conditions
Prostate Cancer
Interventions
Blood draw, Urine sample
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 10, 2026, 9:45 AM EDT
Not listed Phase 2Phase 3 Interventional

Ablatherm Integrated Imaging High Intensity Focused Ultrasound for the Indication of Low Risk, Localized Prostate Cancer

NCT00295802
View directory record Official record
Conditions
Prostate Cancer
Interventions
Integrated Imaging High Intensity Focused Ultrasound, Endocare CRYOcare Cryosurgical and Galil Medical CRYO-HIT Systems (cryotherapy)
Device
Lead sponsor
EDAP TMS S.A.
Industry
Eligibility
50 Years and older · Male only
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
14
States / cities
Arcadia, California • Aurora, Colorado • Ocala, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Sep 10, 2026, 9:45 AM EDT
Completed No phase listed Observational

Registry of Subject Treated With ClariFix

NCT03739216
View directory record Official record
Conditions
Chronic Rhinitis
Interventions
ClariFix
Device
Lead sponsor
Arrinex, Inc.
Industry
Eligibility
Not listed
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
23
States / cities
Bakersfield, California • Marina del Rey, California • Roseville, California + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Phase 2 Interventional

Study of Focal Cryoablation in Low-Risk Prostate Cancer

NCT00774436
View directory record Official record
Conditions
Prostate Cancer
Interventions
focal cryotherapy
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2019 · Synced Sep 10, 2026, 9:45 AM EDT
Recruiting No phase listed Observational

Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer

NCT07184957
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 85 Years · Male only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2040
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 10, 2026, 9:45 AM EDT
Not listed Not applicable Interventional

Microwave Treatment of Common and Plantar Warts

NCT05371834
View directory record Official record
Conditions
Warts
Interventions
Microwave Treatment (Swift System), Cryotherapy
Device
Lead sponsor
Blackwell Device Consulting
Industry
Eligibility
18 Years to 64 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
6
States / cities
Miami, Florida • Palm Harbor, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 10, 2026, 9:45 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Focal Therapy for Localized Prostate Cancer

NCT06270043
View directory record Official record
Conditions
Prostate Cancer
Interventions
Focal Therapy
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2034
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Phase 4 Interventional Results available

Opioid-Free Shoulder Arthroplasty

NCT03540030
View directory record Official record
Conditions
Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear, Arthritis;Inflammatory
Interventions
Gabapentin, Celecoxib, toradol, acetaminophen, regional block, propofol, IV lidocaine, rocuronium, vecuronium, sevoflurane, desflurane
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
50 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 10, 2026, 9:45 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

NCT01783535
View directory record Official record
Conditions
Retinoblastoma
Interventions
vincristine, topotecan, filgrastim, PEG-filgrastim, carboplatin, focal therapy, etoposide, cyclophosphamide, MESNA, doxorubicin, enucleation, external beam radiation or proton beam radiation
Drug · Other · Procedure + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 10, 2026, 9:45 AM EDT
Enrolling by invitation Not applicable Interventional

Fusion Guided Focal Laser Ablation of Prostate Cancer

NCT02759744
View directory record Official record
Conditions
Prostate Cancer, Prostate Neoplasms
Interventions
ultrasound image-guided ablation device
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 10, 2026, 9:45 AM EDT
Recruiting Not applicable Interventional

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

NCT06178354
View directory record Official record
Conditions
Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8
Interventions
Cryosurgery, High-Intensity Focused Ultrasound Ablation, Survey Administration
Procedure · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 10, 2026, 9:45 AM EDT
Completed Not applicable Interventional

Prostate Conformal Cryotherapy

NCT00877682
View directory record Official record
Conditions
Prostate Cancer
Interventions
Cryoablation
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 10, 2026, 9:45 AM EDT