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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Gut Health Response to Dietary Fiber

NCT01321736
Conditions
Dietary Fiber
Interventions
dietary fiber
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Saint Paul, Minnesota
Completed Early Phase 1 Interventional Accepts healthy volunteers

Satiety Response of Four Dietary Fibers

NCT01233024
Conditions
Healthy
Interventions
Control, Soluble corn fiber, Resistant starch, Fructooligosaccharide, Inulin
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Gastrointestinal Symptoms, Weight Loss, GLP-1
Interventions
High Fiber Bar with Inulin, High Fiber bar with Fiber Blend, High Fiber Bar with Resistant Starch type 4, Low Fiber Bar
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
25 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Miami Gardens, Florida • Port Saint Lucie, Florida
Conditions
Prediabetes
Interventions
Inulin, Placebo
Dietary Supplement
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Conditions
IBS (Irritable Bowel Syndrome), Bloating, Abdominal Pain, Gut Health
Interventions
FODMAP-targeting digestive enzyme blend, Placebo
Dietary Supplement · Other
Lead sponsor
Kiwi Health Inc
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Completed Phase 2 Interventional Results available

Inulin for Infections in the Intensive Care Unit

NCT03865706
Conditions
Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders, Critical Illness, Sepsis
Interventions
Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Completed Early Phase 1 Interventional Accepts healthy volunteers

WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study

NCT04543877
Conditions
Inflammation, Vaccine, Intestinal Permeability, Typhoid Fever
Interventions
Inulin, Maltodextrin, Ty21a Typhoid Fever Vaccine
Dietary Supplement · Biological
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Davis, California
Completed Not applicable Interventional Accepts healthy volunteers

Microbiome Fructan Metabolism and Symptoms in Childhood IBS

NCT02842281
Conditions
Irritable Bowel Syndrome (IBS)
Interventions
Fructan, Maltodextrin
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
2
States / cities
Houston, Texas
Conditions
Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Mixed Bowel Habits
Interventions
Dietary Intervention
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Premature Birth of Newborn, Critically Ill
Interventions
Methadone
Drug
Lead sponsor
John van den Anker
Other
Eligibility
22 Weeks to 43 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Conditions
Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
Interventions
Fructanase, Maltodextrin placebo
Dietary Supplement
Lead sponsor
BIO-CAT, Inc.
Industry
Eligibility
20 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Addison, Illinois
Conditions
Asthma in Children
Interventions
Inulin
Drug
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Effects of Prebiotics on Human Behavior and Cognition

NCT04055246
Conditions
Prebiotics and Human Behavior and Cognition
Interventions
Inulin, Placebo (maltodextrin)
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Bone Diseases, Endocrine, Nutritional and Metabolic Diseases
Interventions
Inulin, Maltodextrin
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Knee Osteoarthritis
Interventions
inulin, Maltodextrin (Placebo)
Drug
Lead sponsor
Yale University
Other
Eligibility
40 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Cystic Fibrosis, Dysbiosis
Interventions
Vitamin D3, Placebo vitamin D3, Inulin, Placebo Inulin
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Gastrointestinal Tolerance
Interventions
Inulin, soluble corn fiber
Other
Lead sponsor
Tate & Lyle
Industry
Eligibility
3 Years to 9 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Addison, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

NCT06668922
Conditions
Irritable Bowel Syndrome (IBS)
Interventions
Inulin
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Brain Injuries
Interventions
Inulin
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Polycystic Ovary Syndrome, Anovulation, Hyperandrogenism, Insulin Resistance, Glucose Intolerance, Metabolic Complication
Interventions
Placebo, Inositol
Other · Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Hershey, Pennsylvania • Philadelphia, Pennsylvania
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

NCT03983434
Conditions
IBS - Irritable Bowel Syndrome
Interventions
Inulin
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Fructan Intolerance
Interventions
Sacrosidase Oral Solution, Placebo
Drug
Lead sponsor
QOL Medical, LLC
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Healthy Volunteer Short Chain Fatty Acid Study

NCT05254340
Conditions
Healthy
Interventions
Inulin
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting Phase 2 Interventional

Psyllium in Pediatric IBS

NCT06639984
Conditions
Irritable Bowel Syndrome
Interventions
Psyllium (0.7 g/year of age per day), Psyllium (0.5 g/year of age per day), Placebo, fructans
Drug · Other
Lead sponsor
Dr Bruno Chumpitazi, M.D.
Other
Eligibility
12 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina