Search | Clinical Trials Finder

Conditions: Holoprosencephaly
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: Not listed
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Prenatal Disorder
Interventions: Standard Care, Obstetric Prenatal Genetic Testing Engagement Solution (OPUS) AI Chatbot; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Cleveland, Ohio

Conditions: Breast Cancer
Interventions: Video and Booklet, Factsheet; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 157 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cancer Risk Syndrome
Interventions: AYA-RISE Adolescents and Young Adults Risk Information and Screening Education, Standard clinical visit for genetic counseling; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 12 Years to 24 Years
Enrollment: 115 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 5
States / cities: Atlanta, Georgia • Chicago, Illinois • Boston, Massachusetts + 1 more

Conditions: Genetic Disease, Cancer, Cardiovascular Diseases
Interventions: private web-portal eHealth disclosure of genetic results, eHealth education intervention (web or chatbot); Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
Interventions: counseling intervention, educational intervention, survey administration, psychosocial assessment and care, supportive care; Other · Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 8 Years to 120 Years · Female only
Enrollment: 245 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Boston, Massachusetts

Conditions: BARD1 Gene Mutation, BRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation, Estrogen Receptor Negative, HER2/Neu Negative, MLH1 Gene Mutation, MSH2 Gene Mutation, MSH6 Gene Mutation, PALB2 Gene Mutation, PMS2 Gene Mutation, Progesterone Receptor Negative, RAD51C Gene Mutation, RAD51D Gene Mutation, Triple-Negative Breast Carcinoma
Interventions: Educational Intervention, Genetic Counseling, Laboratory Biomarker Analysis, Questionnaire Administration; Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 30 Years and older · Female only
Enrollment: 5,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 2
States / cities: Houston, Texas • Seattle, Washington

Conditions: Hereditary Cancer, Genetic Testing
Interventions: Relational agent (RA) / Chatbot, Enhanced Usual Care (EUC); Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 80 Years
Enrollment: 428 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • New Brunswick, New Jersey

Conditions: Breast Cancer, Ovarian Cancer
Interventions: telephone interviews; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older · Female only
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer
Interventions: counseling intervention; Other
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2007
U.S. locations: 7
States / cities: Canton, Ohio • Chardonr, Ohio • Mentor, Ohio + 4 more

Conditions: Breast Cancer
Interventions: YouTube Video Arm; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking Cessation, Smoking, Physician's Role
Interventions: Usual care, Precision treatment; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 89 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: St Louis, Missouri

Conditions: Li-Fraumeni Syndrome
Interventions: Questionnaire Administration; Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Not listed
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Patient Education
Interventions: Handout on PGT-A, Handout on PGT-A and genetic counseling; Other
Lead sponsor: Eyup Hakan Duran; Other
Eligibility: 18 Years to 45 Years
Enrollment: 213 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Hereditary Breast and Ovarian Cancer
Interventions: Breast Cancer Genetics Referral Screening Tool 3.0, Standard Handout, Physician Notification, Automatic Follow-Up by Genetic Counseling Staff; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 665 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Gynecologic Cancer, Hereditary Cancer Syndrome
Interventions: Chatbot; Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 4
States / cities: Brooklyn, New York • New York, New York • Queens, New York

Conditions: Solid Tumor Malignancies, Metastatic Cancer, Breast Cancer, Colorectal Cancer, Lung Cancer, Bladder Cancer
Interventions: Expert Review, Blood or tissue samples collection., The Precision Oncology Navigation; Other
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Vaccine Hesitancy, Vaccine Refusal
Interventions: Not listed
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Diabetes Mellitus, Type 2
Interventions: Receiving results via genetic counselor; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Structural Anomalies, Cardiac Anomalies, Central Nervous System Anomalies, Thorax Anomalies, Genito-urinary Anomalies, Gastrointestinal Anomalies, Skeletal Anomalies, Multiple Anomalies
Interventions: Whole Exome Sequencing (WES); Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 64 Years · Female only
Enrollment: 316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Physician's Role, Smoking Cessation, Smoking
Interventions: Precision Treatment, Usual Care; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cancer, Cancer Gene Mutation, PAN Gene Mutation, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Interventions: Pan-genomic Testing; Genetic
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2033
U.S. locations: 3
States / cities: Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Achondroplasia, Dwarfism
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: Not listed
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 2000
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Prostate Carcinoma, Breast Neoplasm, Pancreatic Cancer, BRCA1 Mutation, BRCA2 Mutation
Interventions: Web-based Counseling, Standard Care; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 25 Years to 70 Years · Male only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Search by objective public record fields.

Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly

Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes

Genetic Counseling for Breast Cancer Survivors (GC for BC)

Intervention For Adolescents and Young Adults (AYAs) With Cancer Risk Syndromes

Penn Medicine Biobank Return of Results Program

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Addressing Genomic Disparities in Cancer Survivors

Decision-making Regarding Prophylactic Mastectomy and Oophorectomy in Women Seeking Genetic Counseling and Testing for BRCA1/2 Mutations

Views on Sharing Family Medical History in Healthy Women Undergoing Mammograms or Breast Evaluation

Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video

Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients

Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling

Preimplantation Genetic Testing for Aneuploidy Counseling

Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Understanding of Genetic Risk Information for Type 2 Diabetes

Clinical Utility of Prenatal Whole Exome Sequencing

Personalized Tobacco Treatment in Primary Care (MOTIVATE)

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

Issues Surrounding Prenatal Genetic Testing for Achondroplasia

The Genetic Education for Men Trial: Web-Based Education vs. Standard Care