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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: high caloric intake Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

The Safety and Effectiveness of Low and High Carbohydrate Diets

NCT00079547
View directory record Official record
Conditions
Obesity
Interventions
Low-calorie diet, low-carbohydrate diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Sep 4, 2026, 10:52 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Feedback, Reflection and Morning Evaluation

NCT05509218
View directory record Official record
Conditions
Youth Drinking, Alcohol Drinking
Interventions
Mobile-delivered personalized feedback
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 29 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional

The MONITOR Study: Remote Monitoring Of a Nutrition Intervention To Optimize Treatment Response

NCT06050395
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Quality fo Life Questionnaire (FHSI), Vioscreen Food Frequency Questionnaire (FFQ), Educational Handouts, NutritionCoaching, Follow-Up Survey, Functional Assessment of Anorexia/Cachexia Treatment (FAACT) Questionnaire, Patient Reported Outcomes Measure- Cognitive Function (PROMIS-Cog) Questionnaire
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 4, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Small Extracellular Vesicles and Insulin Action

NCT05933707
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign
Interventions
People with Metabolically Unhealthy Obesity - Low Calorie Diet
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Metabolically Normal and Metabolically Abnormal Obesity

NCT01184170
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
overfeeding
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Phase 2 Interventional

Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care

NCT00842426
View directory record Official record
Conditions
Obesity, Pre-diabetes, Metabolic Syndrome
Interventions
Self-management program (SM), Care management program (CM)
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2012 · Synced Sep 4, 2026, 10:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physiological and Dietary Characteristics of Boys and Girls High School Basketball Players

NCT05658159
View directory record Official record
Conditions
Bone Health
Interventions
Vitamin D, DXA scan, Nutrition analysis
Diagnostic Test · Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
14 Years to 19 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Very Low Carbohydrate Diet as an Adjunctive Therapy for Youth Type 1 Diabetes

NCT04082884
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Very Low Carbohydrate Diet
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 25 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial Comparing Two Approaches to Weight Loss

NCT02671110
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Transforming Your Life, Diabetes Prevention Program
Behavioral
Lead sponsor
Robert Carels
Other
Eligibility
21 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bowling Green, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Pecan Nut Snacks v Equicaloric Snacks on Appetite, Food Intake, Metabolism, Hormones and Biomarkers

NCT04484974
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Pecan snack, Tortilla chip snack
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 4, 2024 · Synced Sep 4, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Protein and Polycystic Ovary Syndrome (PCOS)

NCT07158723
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Higher protein dietary pattern, Calorie restriction
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol

NCT02169245
View directory record Official record
Conditions
Brain Activity, Appetite, Ingestive Behavior, Glucose Control, Cholesterol
Interventions
Dietary control of protein and fiber intake at breakfast
Other
Lead sponsor
Purdue University
Other
Eligibility
21 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
West Lafayete, Indiana • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis

NCT01939262
View directory record Official record
Conditions
Osteoarthritis
Interventions
Limitation of Animal Fat and Protein in the Diet, Control
Other
Lead sponsor
Essentia Health
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Traverse City, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Sep 4, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Ester and Salt (KEAS) in Young Adults

NCT05545501
View directory record Official record
Conditions
Salt; Excess, Hypertension
Interventions
No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
19 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Methods for Reducing Obesity Risk in Parents and Children

NCT03973424
View directory record Official record
Conditions
Overweight and Obesity, Overweight, Obesity
Interventions
Simple, Standard
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
2 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 4, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ultra-processed Food Consumption and Health Pilot Study

NCT07318064
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Purple Diet, Ultra-processed diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Based Treatment for Weight Loss With Breakfast Prescription

NCT02467036
View directory record Official record
Conditions
Obesity, Overweight, Overeating, Weight, Childhood Obesity
Interventions
Family Based Behavioral Treatment
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Energy Flux Study

NCT01736098
View directory record Official record
Conditions
Physical Activity
Interventions
Energy Flux Exercise Intervention
Other
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 45 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

NCT02984540
View directory record Official record
Conditions
Mild Cognitive Impairment, Insulin Resistance
Interventions
Low-Carbohydrate Diet, Low-Fat Diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Environmental Costs of Building Human Muscle

NCT06733857
View directory record Official record
Conditions
Greenhouse Gas Emissions, Water Use, Land Use
Interventions
VEG2, OMNI2
Behavioral
Lead sponsor
Game Changers Institute
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laguna Niguel, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 4, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Efficacy and Safety of the DASH Diet in Adults With Moderate Chronic Kidney Disease: Pilot Study

NCT02059811
View directory record Official record
Conditions
Hypertension, Chronic Kidney Disease
Interventions
DASH Diet, Control Diet
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2014 · Synced Sep 4, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional

Solutions for Hunger And Regulating Eating

NCT05004883
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Regulation of Cues Enhanced, Behavioral Weight Loss, Nutrition Education, Stress Management and Social Support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 4, 2026, 10:52 PM EDT