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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:48 PM EDT

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Showing 121–144 of 233 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: high-fiber Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

HFS (High-Fiber Supplement) in MS (Multiple Sclerosis)

NCT04574024
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
NBT-NM108
Drug
Lead sponsor
Suhayl Dhib-Jalbut, MD
Other
Eligibility
21 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 22, 2026, 3:48 PM EDT
Recruiting Not applicable Interventional

Study of Nutrition and Exercise in Adults Hospitalized for Treatment of Acute Lymphoblastic Leukemia (ALL)

NCT06785324
View directory record Official record
Conditions
Philadelphia Chromosome Negative, B Cell Acute Lymphoblastic Leukemia (B-ALL), B-ALL
Interventions
Nutrition Intervention, Exercise intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cancer Dietary Objectives Study

NCT00561977
View directory record Official record
Conditions
Cancer, Heart Disease
Interventions
High Fiber Diet, low saturated fat diet, Combination diet
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2011 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR)

NCT02445963
View directory record Official record
Conditions
Shigellosis, Bacillary Dysentery
Interventions
Shigella flexneri 2a InvaplexAR
Biological
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 45 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Highly Processed Foods and Vascular Health

NCT05628350
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
No UPF controlled diet, High UPF controlled diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hunger and Learning Study in Preschoolers

NCT03861208
View directory record Official record
Conditions
Hunger, Ingestive Behavior, Obesity, Food Preferences
Interventions
diet, usual diet
Other
Lead sponsor
University of Virginia
Other
Eligibility
3 Years to 4 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of a Chickpea Pasta on Gut Health, Blood Glucose, and Overall Health

NCT07264465
View directory record Official record
Conditions
Gut Health, Gastrointestinal Health
Interventions
Chickpea Pasta
Dietary Supplement
Lead sponsor
Banza LLC
Industry
Eligibility
21 Years to 44 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ButyraGen™, Short Chain Fatty Acids and Gut Microbiome

NCT05601635
View directory record Official record
Conditions
Healthy
Interventions
ButyraGen™
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Gastrointestinal Responses to Dietary Fibers in Adults Using Weight Loss Medications

NCT07012317
View directory record Official record
Conditions
Gastrointestinal Symptoms, Weight Loss, GLP-1
Interventions
High Fiber Bar with Inulin, High Fiber bar with Fiber Blend, High Fiber Bar with Resistant Starch type 4, Low Fiber Bar
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
25 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Miami Gardens, Florida • Port Saint Lucie, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Results available

Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy.

NCT04281875
View directory record Official record
Conditions
Postoperative Hypoparathyroidism, Thyroid Neoplasms, Thyroid Cancer
Interventions
NIRAF Detection Technology
Device
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of High Fiber Snacks on Adiposity, Glucose Regulation and Appetite

NCT02217124
View directory record Official record
Conditions
Obesity
Interventions
dried apples, muffin
Other
Lead sponsor
San Diego State University
Other
Eligibility
10 Years to 16 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2017 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional

Managing Pain in Patients With MTP Arthritis

NCT04833608
View directory record Official record
Conditions
Hallux Rigidus
Interventions
Vktory insoles, Morton's extension insoles
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2021 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Thermic & Lipemic Properties of Dietary Carbohydrates

NCT01354574
View directory record Official record
Conditions
Exogenous Obesity, Dietary Modification
Interventions
High Glycemic Index meals, Low Glycemic Index meals
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 48 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Excessive Weight Gain and Maternal and Infant Fat Accretion

NCT04868110
View directory record Official record
Conditions
Gestational Weight Gain, Maternal Fat Accretion, Infant Fat Accretion
Interventions
High fiber diet
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 22, 2026, 3:48 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

NCT05276232
View directory record Official record
Conditions
Cannabis
Interventions
Cannabis(THC) inhaled
Drug
Lead sponsor
ISBRG Corp
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk

NCT03550885
View directory record Official record
Conditions
Colorectal Cancer
Interventions
High taurine and saturated fat diet, Low in taurine and saturated fat diet
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Terminated Not applicable Interventional

An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds

NCT05494450
View directory record Official record
Conditions
Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
ExufiberAG+
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
San Francisco, California • Miamisburg, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 22, 2026, 3:48 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)

NCT07407777
View directory record Official record
Conditions
Gastrointestinal Discomfort, Digestive Well Being, Gut-related Symptoms
Interventions
Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris)
Dietary Supplement
Lead sponsor
Koralo GmbH
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Phase 1 Interventional

Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy

NCT00486304
View directory record Official record
Conditions
Cachexia, Head and Neck Cancer, Weight Changes
Interventions
ADD, Placebo
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2012 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional

Facts-Up-Front Versus Traffic-Light Food Labels

NCT01626729
View directory record Official record
Conditions
Food Labeling
Interventions
Traffic Light+, Facts Up Front+, No label control group
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
703 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2012 · Synced Oct 22, 2026, 3:48 PM EDT
Recruiting Phase 1Phase 2 Interventional

Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery

NCT06349590
View directory record Official record
Conditions
Colorectal Cancer
Interventions
High-fiber/low-fat meals
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Completed Not applicable Interventional

Snacking, Satiety &Weight: A Randomized, Controlled Trial

NCT02050165
View directory record Official record
Conditions
Obesity
Interventions
KIND Bars, Typical American Snack
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
25 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 22, 2026, 3:48 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

NCT06075914
View directory record Official record
Conditions
Sleep Deprivation, Nutritional Intervention
Interventions
Ketogenic Intervention, Mediterranean Intervention, Placebo, Ketone Ester
Other · Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 22, 2026, 3:48 PM EDT
Recruiting Not applicable Interventional

Effects of Pistachios on Postprandial Metabolic Responses in Adults With Overweight or Obesity

NCT07853898
View directory record Official record
Conditions
Obesity / Overweight
Interventions
Pistachio Co-consumption, Refined-Carbohydrate Control Co-consumption
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 35 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 22, 2026, 3:48 PM EDT