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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: humeral fracture Clear all
Completed No phase listed Observational

Operative Versus Nonoperative Treatment of Humeral Shaft Fractures: A Prospective Cohort Comparison Study

NCT01363518
View directory record Official record
Conditions
Closed Fracture of Shaft of Humerus
Interventions
Not listed
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 65 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
7
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Burlington, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced Sep 14, 2026, 2:19 PM EDT
Recruiting No phase listed Observational

Duration of Immobilization After Reverse Total Arthroplasty for Proximal Humerus Fractures

NCT06133920
View directory record Official record
Conditions
Proximal Humeral Fracture, Reverse Total Shoulder Arthroplasty
Interventions
Early Range of Motion, Immobilization
Other
Lead sponsor
The Cooper Health System
Other
Eligibility
60 Years and older
Enrollment
40 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Sep 14, 2026, 2:19 PM EDT
Enrolling by invitation Not applicable Interventional

Anxiety Surrounding Supracondylar Pin Removal in Children: A Randomized Controlled Trial

NCT05501834
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Anxiety
Interventions
Supracondylar Pin Removal After Imaging With VR, Supracondylar Pin Removal Before Imaging, Supracondylar Pin Removal Before Imaging With VR
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 10 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Acute Management of Humeral Shaft Fractures: Sling vs. Splint

NCT01869322
View directory record Official record
Conditions
Fracture of Shaft of Humerus
Interventions
Sling and Swathe, Coaptation Splint
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated No phase listed Observational

Tornier Shoulder Outcomes Study to Examine Safety and Functional Outcomes in Shoulder Arthroplasty and Fracture Patients

NCT02047955
View directory record Official record
Conditions
Shoulder Arthroplasty and Fracture Repair
Interventions
Shoulder Arthroplasty
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
7,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
15
States / cities
Birmingham, Alabama • San Francisco, California • Denver, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated No phase listed Observational Results available

A Post-Market Clinical Evaluation of the ReUnion Reversible Fracture (RFX) System

NCT04089371
View directory record Official record
Conditions
Arthroplasty, Hemiarthroplasty, Shoulder Pain
Interventions
ReUnion Total Shoulder Arthroplasty (TSA), ReUnion Reverse Shoulder Arthroplasty (RSA)
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Peoria, Illinois • Greenville, South Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Sep 14, 2026, 2:19 PM EDT
Active, not recruiting No phase listed Observational

Perform® Humeral System - Fracture Study (PFX)

NCT05773352
View directory record Official record
Conditions
Traumatic Arthropathy of Shoulder, Fracture Humerus, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains
Interventions
Tornier Perform® Humeral System - Fracture
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
9
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Rancho Mirage, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Active, not recruiting No phase listed Observational

Affixus Natural Nail System Humeral Nail PMCF

NCT05019664
View directory record Official record
Conditions
Humeral Fractures, Proximal, Humeral Fractures
Interventions
humeral fracture
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated Not applicable Interventional Results available

Total vs. Reverse Shoulder Replacement: Pain Relief Two Years After Surgery

NCT01884077
View directory record Official record
Conditions
Arthritis
Interventions
Reverse Shoulder Arthroplasty, Total Shoulder Arthroplasty
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
70 Years to 95 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 14, 2026, 2:19 PM EDT
Completed Phase 4 Interventional Results available

Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management

NCT06187584
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
5 Years to 9 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated No phase listed Observational

Post-Approval Prospective Study - Conventus CAGE™ PH for Use in Proximal Humerus Fracture Fixation

NCT03489408
View directory record Official record
Conditions
Humeral Fractures, Proximal
Interventions
Conventus Cage™ PH
Device
Lead sponsor
Conventus Orthopaedics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
5
States / cities
Redwood City, California • Torrance, California • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 14, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture

NCT06869343
View directory record Official record
Conditions
Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
Interventions
Physical Therapy
Other
Lead sponsor
University of Virginia
Other
Eligibility
50 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated No phase listed Observational

Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty

NCT01480453
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3- and 4-part Proximal Humeral Fractures, Avascular Necrosis
Interventions
Trabecular Metal Humeral Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
3
States / cities
Louisville, Kentucky • Royal Oak, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Sep 14, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Comparison of Bracing With Co-aptation Splinting for the Initial Treatment of Acute Humeral Shaft Fractures: The COBRAS Trials

NCT05118087
View directory record Official record
Conditions
Humeral Fractures
Interventions
Webril Padded Plaster Splint, Pre-Fabricated Fracture Brace
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Garden City, New York • New York, New York • Queens, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Active, not recruiting Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

NCT03626038
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Psoriatic Arthritis, Proximal Humeral Fracture
Interventions
A.L.P.S. Proximal Humerus Plating System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Completed No phase listed Observational

Pediatric Supracondylar Humerus Fracture NIRS Study

NCT01808183
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Near Infrared Spectroscopy Pads
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
2 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated Not applicable Interventional

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

NCT02597972
View directory record Official record
Conditions
Closed Fracture Proximal Humerus, Four Part
Interventions
Fracture repair, Fracture repair with joint replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 14, 2026, 2:19 PM EDT
Recruiting Phase 4 Interventional

Supracondylar Post-Operative Pain Study

NCT03759028
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Ibuprofen, Oxycodone, Acetaminophen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Not listed Phase 4 Interventional

NovaLign Intramedullary Fixation System (IFS) for the Treatment of Humeral Fractures

NCT00969839
View directory record Official record
Conditions
Fracture
Interventions
NovaLign Intramedullary Fixation System
Device
Lead sponsor
NovaLign Orthopaedics, Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Denver, Colorado • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 17, 2009 · Synced Sep 14, 2026, 2:19 PM EDT
Terminated Not applicable Interventional

RSA vs. Nonop for 3 & 4-Part Proximal Humerus Fractures

NCT03599336
View directory record Official record
Conditions
Humerus Fracture, Humerus, Shoulder Fractures, Shoulder Arthropathy Associated With Other Conditions, Arthropathy Shoulder, Shoulder Injury, Arthropathy
Interventions
Reverse Total Shoulder Arthroplasty (rTSA), Nonoperative Treatment
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 14, 2026, 2:19 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Regional Blocks for Lateral Condyle Fractures

NCT03796572
View directory record Official record
Conditions
Fractures, Closed, Humeral Fractures, Pain
Interventions
Ropivacaine, Puncture Wound and Dressing
Drug · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Active, not recruiting No phase listed Observational

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

NCT01480440
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3-and 4-part Proximal Humeral Fractures, Avascular Necrosis, Gross Rotator Cuff Deficiency, Revision Total Shoulder Arthroplasty
Interventions
Trabecular Metal Reverse Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • Egg Harbor, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 14, 2026, 2:19 PM EDT
Recruiting No phase listed Observational

Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-up

NCT05703958
View directory record Official record
Conditions
Proximal Humeral Fracture, Fracture Dislocation, Non-Union Fracture
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 14, 2026, 2:19 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Retrospective Analysis on Distal Humerus Fractures

NCT03637621
View directory record Official record
Conditions
Distal Humerus Fracture
Interventions
ORIF
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 14, 2026, 2:19 PM EDT