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ClinicalTrials.gov public records Last synced Oct 28, 2026, 10:22 AM EDT

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Showing 1249–1272 of 1,541 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: increased exercise Clear all
Completed Not applicable Interventional Results available

Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation

NCT02631850
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Traditional CI Therapy, Gaming CI Therapy, Gaming CI Therapy with Additional Contact via Video Conference, Traditional Occupational Therapy/Physical Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Birmingham, Alabama • Columbia, Missouri • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

A Pilot Study Using Weightloss and Exercise to Prevent Recurring Gestational Diabetes in Obese Women

NCT00924599
View directory record Official record
Conditions
Gestational Diabetes
Interventions
Prevention of recurrent gestational diabetes through weight loss and exercise (English & Spanish), Lifestyle education (English & Spanish)
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2016 · Synced Oct 28, 2026, 10:22 AM EDT
Recruiting Phase 2 Interventional

SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

NCT05138575
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

Feasibility of Resistance Exercise to Treat Major Depression Via Cerebrovascular Mechanisms

NCT05695365
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Resistance Exercise Training
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Míranos! Program, a Preschool Obesity Prevention RCT

NCT03590834
View directory record Official record
Conditions
Obesity, Healthy Eating, Physical Activity, Health Knowledge, Attitudes, Practice, Gross Motor Development
Interventions
Center-based Intervention, Home-based Intervention, Active Control
Behavioral
Lead sponsor
The University of Texas at San Antonio
Other
Eligibility
3 Years to 5 Years
Enrollment
525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MEMORI Corps: Activity-based Companion Care for Dementia

NCT03896711
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
MEMORI Corps program, Augmented Waitlist Control
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 115 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Results available

Smartphone App to Improve Physical Activity in Older Adults With MCI/Mild Dementia

NCT04950998
View directory record Official record
Conditions
Sedentary Lifestyle, Dementia, Mild, Mild Cognitive Impairment, Memory and Thinking Problems
Interventions
Moving Up - A
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
65 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Oct 28, 2026, 10:22 AM EDT
Recruiting Not applicable Interventional

Cardiometabolic Health Intervention Using Movement-to-Music Exercise

NCT05606432
View directory record Official record
Conditions
Cardiometabolic Risk Factors in Adult Wheelchair Users
Interventions
Instructor-led, one-on-one M2M exercise group, Self-guided control with pre-recorded standard exercise videos
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Results available

Changing Lifestyles for Better Health

NCT00848757
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Nutrition, Exercise, and Wellness Treatment (NEW Tx) for Bipolar Disorder

NCT01615367
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Nutrition, Exercise, and Wellness (NEW) psychotherapy, Typically consists of at least one FDA-approved mood stabilizer
Other · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 28, 2026, 10:22 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions

NCT01306994
View directory record Official record
Conditions
Arthrogryposis, Craniofacial Abnormalities
Interventions
Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form, Strength, Joint ROM, Girth and Length Measurements, Study Physical Examination, Observational Gait Analysis, Mental Health Interview
Other · Procedure
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Women's Walking Program

NCT01700894
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Walking Program + Motivational Interviewing Calls, Walking Program + Automated Calls, Walking Program
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
288 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
7
States / cities
Chicago, Illinois • Oak Park, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2013 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Basal Metabolic Rate in Postmenopausal Women

NCT01550536
View directory record Official record
Conditions
Postmenopausal Metabolic Health
Interventions
Resistance and aerobic exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 120 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
3
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 28, 2026, 10:22 AM EDT
Active, not recruiting Phase 2 Interventional

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

NCT04742751
View directory record Official record
Conditions
PreDiabetes, Adult Children
Interventions
Metformin, Digital Intervention
Drug · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 44 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Phase 4 Interventional Results available

An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)

NCT01338636
View directory record Official record
Conditions
Exercise-induced Pulmonary Arterial Hypertension
Interventions
Ambrisentan
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Results available

Improving Diabetes in Emerging Adulthood

NCT04066959
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Motivational Enhancement System (MES), Question Prompt List (QPL), Text Message Reminders (TXT)
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
16 Years to 25 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Phase 2 Interventional

Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension

NCT00352482
View directory record Official record
Conditions
Pulmonary Fibrosis, Hypertension, Pulmonary
Interventions
Sildenafil (50 mg)
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

Engaging African American Older Adults With Arthritis in a Physical Activity Intervention

NCT05652413
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Adapted-Engage-PA
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 28, 2026, 10:22 AM EDT
Active, not recruiting Not applicable Interventional

Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center

NCT06712797
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma, Intraductal Papillary Mucinous Neoplasm
Interventions
Physical Activity (PA), Nutrition (N)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Results available

Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes

NCT02473926
View directory record Official record
Conditions
Motor Activity, Health Behavior, Diabetes Mellitus, Type 2
Interventions
Physical Activity, Questionnaires
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

Early Mobilization in the ICU

NCT01777035
View directory record Official record
Conditions
Respiratory Failure
Interventions
early PT OT
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional Results available

A New Training to Enhance Physical Activity in Adolescents With Cerebral Palsy

NCT05865418
View directory record Official record
Conditions
Cerebral Palsy, Muscle Disorder, Physical Disability, Posture Disorders in Children, Spina Bifida
Interventions
Loaded high intensity training, High intensity circuit training (HICT)
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
11 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

High Intensity Body-weight Circuit Training in Type 2 Diabetics

NCT04515992
View directory record Official record
Conditions
Type2 Diabetes
Interventions
High Intensity Body-weight Circuit Training (HIBC)
Behavioral
Lead sponsor
Kennesaw State University
Other
Eligibility
45 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Oct 28, 2026, 10:22 AM EDT
Completed Not applicable Interventional

Weight Reduction Intervention for Breast Cancer Survivors

NCT00774371
View directory record Official record
Conditions
Breast Cancer
Interventions
Cognitive behavioral therapy CBT) for weight loss
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 28, 2026, 10:22 AM EDT